{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 770
    },
    {
      "term": "NAUSEA",
      "count": 515
    },
    {
      "term": "PNEUMONIA",
      "count": 500
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 420
    },
    {
      "term": "VOMITING",
      "count": 403
    },
    {
      "term": "DIARRHOEA",
      "count": 390
    },
    {
      "term": "PYREXIA",
      "count": 386
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 383
    },
    {
      "term": "FATIGUE",
      "count": 253
    },
    {
      "term": "DYSPNOEA",
      "count": 252
    },
    {
      "term": "DEATH",
      "count": 248
    },
    {
      "term": "RASH",
      "count": 244
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 241
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 241
    },
    {
      "term": "CHOLELITHIASIS",
      "count": 227
    },
    {
      "term": "NEUTROPENIA",
      "count": 227
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 211
    },
    {
      "term": "SCHIZOPHRENIA",
      "count": 210
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 197
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 193
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 184
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 181
    },
    {
      "term": "PANCYTOPENIA",
      "count": 178
    },
    {
      "term": "ANAEMIA",
      "count": 177
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 169
    },
    {
      "term": "COVID-19",
      "count": 164
    },
    {
      "term": "SEPSIS",
      "count": 163
    },
    {
      "term": "HEADACHE",
      "count": 161
    },
    {
      "term": "HYPOMANIA",
      "count": 159
    },
    {
      "term": "PSYCHOTIC DISORDER",
      "count": 155
    },
    {
      "term": "JAUNDICE CHOLESTATIC",
      "count": 154
    },
    {
      "term": "PAIN",
      "count": 152
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 150
    },
    {
      "term": "ASTHENIA",
      "count": 149
    },
    {
      "term": "COUGH",
      "count": 147
    },
    {
      "term": "DRUG INTERACTION",
      "count": 147
    },
    {
      "term": "PNEUMOCYSTIS JIROVECII PNEUMONIA",
      "count": 142
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 140
    },
    {
      "term": "RENAL FAILURE",
      "count": 139
    },
    {
      "term": "DECREASED APPETITE",
      "count": 126
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 118
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 117
    },
    {
      "term": "DIZZINESS",
      "count": 112
    },
    {
      "term": "GASTROOESOPHAGEAL REFLUX DISEASE",
      "count": 106
    },
    {
      "term": "BRONCHIECTASIS",
      "count": 105
    },
    {
      "term": "HEPATIC CYTOLYSIS",
      "count": 104
    },
    {
      "term": "WHEEZING",
      "count": 104
    },
    {
      "term": "CHRONIC OBSTRUCTIVE PULMONARY DISEASE",
      "count": 103
    },
    {
      "term": "PRURITUS",
      "count": 103
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 100
    },
    {
      "term": "RHINITIS ALLERGIC",
      "count": 98
    },
    {
      "term": "ASTHMA-CHRONIC OBSTRUCTIVE PULMONARY DISEASE OVERLAP SYNDROME",
      "count": 97
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 97
    },
    {
      "term": "HYPOTENSION",
      "count": 97
    },
    {
      "term": "NASAL POLYPS",
      "count": 97
    },
    {
      "term": "SARCOIDOSIS",
      "count": 97
    },
    {
      "term": "ANXIETY",
      "count": 96
    },
    {
      "term": "CARDIAC MURMUR",
      "count": 96
    },
    {
      "term": "TOTAL LUNG CAPACITY INCREASED",
      "count": 96
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 95
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 95
    },
    {
      "term": "CONSTIPATION",
      "count": 94
    },
    {
      "term": "MALAISE",
      "count": 94
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 93
    },
    {
      "term": "NOCARDIOSIS",
      "count": 89
    },
    {
      "term": "THROMBOTIC MICROANGIOPATHY",
      "count": 88
    },
    {
      "term": "CHILLS",
      "count": 86
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 86
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 85
    },
    {
      "term": "HYPERTENSION",
      "count": 85
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 84
    },
    {
      "term": "LUNG NEOPLASM MALIGNANT",
      "count": 84
    },
    {
      "term": "INFECTION",
      "count": 83
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 83
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 82
    },
    {
      "term": "INSOMNIA",
      "count": 78
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 74
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 74
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 73
    },
    {
      "term": "HOSPITALISATION",
      "count": 70
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 70
    },
    {
      "term": "LEUKOPENIA",
      "count": 68
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 67
    },
    {
      "term": "COLITIS",
      "count": 67
    },
    {
      "term": "FALL",
      "count": 67
    },
    {
      "term": "ARTHRALGIA",
      "count": 66
    },
    {
      "term": "BACK PAIN",
      "count": 66
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 66
    },
    {
      "term": "CHOLESTASIS",
      "count": 65
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 65
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE",
      "count": 64
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 64
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 63
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 63
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 62
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 62
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 61
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 60
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 60
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 60
    }
  ]
}