{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DIFFERENTIATION SYNDROME",
      "count": 184
    },
    {
      "term": "OFF LABEL USE",
      "count": 145
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 127
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 67
    },
    {
      "term": "PYREXIA",
      "count": 49
    },
    {
      "term": "IDIOPATHIC INTRACRANIAL HYPERTENSION",
      "count": 46
    },
    {
      "term": "ACUTE PROMYELOCYTIC LEUKAEMIA DIFFERENTIATION SYNDROME",
      "count": 45
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 41
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 37
    },
    {
      "term": "NEUTROPENIA",
      "count": 37
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 37
    },
    {
      "term": "LEUKAEMIA RECURRENT",
      "count": 36
    },
    {
      "term": "ANAEMIA",
      "count": 35
    },
    {
      "term": "DYSPNOEA",
      "count": 34
    },
    {
      "term": "WHITE BLOOD CELL COUNT INCREASED",
      "count": 34
    },
    {
      "term": "DIARRHOEA",
      "count": 33
    },
    {
      "term": "PNEUMONIA",
      "count": 33
    },
    {
      "term": "DEATH",
      "count": 32
    },
    {
      "term": "FATIGUE",
      "count": 32
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 32
    },
    {
      "term": "HYPOTENSION",
      "count": 29
    },
    {
      "term": "NAUSEA",
      "count": 27
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 27
    },
    {
      "term": "VOMITING",
      "count": 27
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 26
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 25
    },
    {
      "term": "PERICARDITIS",
      "count": 25
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 25
    },
    {
      "term": "HYPERLEUKOCYTOSIS",
      "count": 24
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 23
    },
    {
      "term": "DRUG INTERACTION",
      "count": 23
    },
    {
      "term": "HEADACHE",
      "count": 23
    },
    {
      "term": "LEUKOCYTOSIS",
      "count": 23
    },
    {
      "term": "SEPSIS",
      "count": 23
    },
    {
      "term": "INFECTION",
      "count": 22
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 22
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME TRANSFORMATION",
      "count": 22
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 21
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 21
    },
    {
      "term": "PERICARDIAL EFFUSION",
      "count": 21
    },
    {
      "term": "DISSEMINATED INTRAVASCULAR COAGULATION",
      "count": 20
    },
    {
      "term": "NEUROTOXICITY",
      "count": 20
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 19
    },
    {
      "term": "ACUTE PROMYELOCYTIC LEUKAEMIA",
      "count": 18
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 16
    },
    {
      "term": "LEUKOPENIA",
      "count": 16
    },
    {
      "term": "LYMPHOPENIA",
      "count": 16
    },
    {
      "term": "MYOCLONUS",
      "count": 16
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 16
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 16
    },
    {
      "term": "ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED",
      "count": 15
    },
    {
      "term": "CHILLS",
      "count": 15
    },
    {
      "term": "HYPOXIA",
      "count": 15
    },
    {
      "term": "INTRACRANIAL PRESSURE INCREASED",
      "count": 15
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 15
    },
    {
      "term": "ASTHENIA",
      "count": 14
    },
    {
      "term": "BONE MARROW NECROSIS",
      "count": 14
    },
    {
      "term": "HERPES ZOSTER",
      "count": 14
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 14
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 14
    },
    {
      "term": "PANCYTOPENIA",
      "count": 14
    },
    {
      "term": "SECOND PRIMARY MALIGNANCY",
      "count": 14
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 13
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 13
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 13
    },
    {
      "term": "CARDIAC ARREST",
      "count": 13
    },
    {
      "term": "DISTURBANCE IN ATTENTION",
      "count": 13
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 13
    },
    {
      "term": "HAEMATOPOIETIC NEOPLASM",
      "count": 13
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 12
    },
    {
      "term": "PAPILLOEDEMA",
      "count": 12
    },
    {
      "term": "RASH",
      "count": 12
    },
    {
      "term": "RENAL FAILURE",
      "count": 12
    },
    {
      "term": "TRANSAMINASES INCREASED",
      "count": 12
    },
    {
      "term": "CEREBRAL HAEMORRHAGE",
      "count": 11
    },
    {
      "term": "COUGH",
      "count": 11
    },
    {
      "term": "HYPERAESTHESIA",
      "count": 11
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 11
    },
    {
      "term": "OSTEONECROSIS OF JAW",
      "count": 11
    },
    {
      "term": "TACHYCARDIA",
      "count": 11
    },
    {
      "term": "TORSADE DE POINTES",
      "count": 11
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 10
    },
    {
      "term": "BONE PAIN",
      "count": 10
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 10
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 10
    },
    {
      "term": "HAEMORRHAGE",
      "count": 10
    },
    {
      "term": "HALLUCINATION, VISUAL",
      "count": 10
    },
    {
      "term": "MYOCARDITIS",
      "count": 10
    },
    {
      "term": "PARAESTHESIA",
      "count": 10
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 10
    },
    {
      "term": "ANXIETY",
      "count": 9
    },
    {
      "term": "AXONAL NEUROPATHY",
      "count": 9
    },
    {
      "term": "BACK PAIN",
      "count": 9
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 9
    },
    {
      "term": "FALL",
      "count": 9
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 9
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 9
    },
    {
      "term": "LUNG INFILTRATION",
      "count": 9
    },
    {
      "term": "NORMAL NEWBORN",
      "count": 9
    },
    {
      "term": "SUBARACHNOID HAEMORRHAGE",
      "count": 9
    }
  ]
}