{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 1957
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1723
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 1463
    },
    {
      "term": "HEADACHE",
      "count": 1371
    },
    {
      "term": "SYNOVITIS",
      "count": 1365
    },
    {
      "term": "FATIGUE",
      "count": 1342
    },
    {
      "term": "NAUSEA",
      "count": 1342
    },
    {
      "term": "RASH",
      "count": 1327
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 1315
    },
    {
      "term": "PAIN",
      "count": 1286
    },
    {
      "term": "HYPERTENSION",
      "count": 1274
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 1262
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 1256
    },
    {
      "term": "JOINT SWELLING",
      "count": 1220
    },
    {
      "term": "ARTHRALGIA",
      "count": 1213
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 1207
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 1179
    },
    {
      "term": "DIARRHOEA",
      "count": 1172
    },
    {
      "term": "HAND DEFORMITY",
      "count": 1171
    },
    {
      "term": "WOUND",
      "count": 1168
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 1158
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 1143
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 1142
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 1142
    },
    {
      "term": "GLOSSODYNIA",
      "count": 1141
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 1130
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 1128
    },
    {
      "term": "ALOPECIA",
      "count": 1122
    },
    {
      "term": "ARTHROPATHY",
      "count": 1114
    },
    {
      "term": "PERICARDITIS",
      "count": 1071
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 1070
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 1066
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 1066
    },
    {
      "term": "SWELLING",
      "count": 1053
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 1036
    },
    {
      "term": "PEMPHIGUS",
      "count": 1035
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 1014
    },
    {
      "term": "VOMITING",
      "count": 1010
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 1004
    },
    {
      "term": "HELICOBACTER INFECTION",
      "count": 996
    },
    {
      "term": "FOLLICULITIS",
      "count": 984
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 966
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 966
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 961
    },
    {
      "term": "URTICARIA",
      "count": 954
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 948
    },
    {
      "term": "FIBROMYALGIA",
      "count": 947
    },
    {
      "term": "MALAISE",
      "count": 945
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 942
    },
    {
      "term": "DECREASED APPETITE",
      "count": 932
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 924
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 918
    },
    {
      "term": "WHEEZING",
      "count": 917
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 911
    },
    {
      "term": "INJURY",
      "count": 910
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 906
    },
    {
      "term": "BLISTER",
      "count": 904
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 893
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 884
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 851
    },
    {
      "term": "LIVER INJURY",
      "count": 831
    },
    {
      "term": "INFLAMMATION",
      "count": 829
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 828
    },
    {
      "term": "SLEEP DISORDER",
      "count": 826
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 821
    },
    {
      "term": "STOMATITIS",
      "count": 807
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 792
    },
    {
      "term": "INSOMNIA",
      "count": 783
    },
    {
      "term": "INFECTION",
      "count": 781
    },
    {
      "term": "MUSCLE INJURY",
      "count": 774
    },
    {
      "term": "C-REACTIVE PROTEIN ABNORMAL",
      "count": 764
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 759
    },
    {
      "term": "JOINT RANGE OF MOTION DECREASED",
      "count": 757
    },
    {
      "term": "WOUND INFECTION",
      "count": 756
    },
    {
      "term": "DIZZINESS",
      "count": 747
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 736
    },
    {
      "term": "DYSPEPSIA",
      "count": 728
    },
    {
      "term": "GAIT INABILITY",
      "count": 726
    },
    {
      "term": "ASTHENIA",
      "count": 725
    },
    {
      "term": "DYSPNOEA",
      "count": 718
    },
    {
      "term": "GRIP STRENGTH DECREASED",
      "count": 718
    },
    {
      "term": "DISCOMFORT",
      "count": 709
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 709
    },
    {
      "term": "PNEUMONIA",
      "count": 708
    },
    {
      "term": "DEPRESSION",
      "count": 702
    },
    {
      "term": "BURSITIS",
      "count": 696
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 687
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 666
    },
    {
      "term": "SWOLLEN JOINT COUNT INCREASED",
      "count": 666
    },
    {
      "term": "HYPERCHOLESTEROLAEMIA",
      "count": 657
    },
    {
      "term": "SINUSITIS",
      "count": 657
    },
    {
      "term": "PRURITUS",
      "count": 644
    },
    {
      "term": "RHEUMATOID FACTOR POSITIVE",
      "count": 640
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 637
    },
    {
      "term": "FACET JOINT SYNDROME",
      "count": 625
    },
    {
      "term": "DRY MOUTH",
      "count": 609
    },
    {
      "term": "PYREXIA",
      "count": 605
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 604
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 601
    },
    {
      "term": "BREAST CANCER STAGE III",
      "count": 597
    }
  ]
}