{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "PHARMACEUTICAL PRODUCT COMPLAINT",
      "count": 760
    },
    {
      "term": "ADVERSE EVENT",
      "count": 722
    },
    {
      "term": "HAEMORRHAGE",
      "count": 298
    },
    {
      "term": "HAEMARTHROSIS",
      "count": 225
    },
    {
      "term": "HIV INFECTION",
      "count": 171
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 166
    },
    {
      "term": "HEPATITIS C VIRUS",
      "count": 125
    },
    {
      "term": "FACTOR VIII INHIBITION",
      "count": 107
    },
    {
      "term": "ANTI FACTOR VIII ANTIBODY POSITIVE",
      "count": 90
    },
    {
      "term": "ARTHRALGIA",
      "count": 78
    },
    {
      "term": "HEPATITIS C",
      "count": 74
    },
    {
      "term": "FALL",
      "count": 72
    },
    {
      "term": "HAEMATOMA",
      "count": 57
    },
    {
      "term": "CONTUSION",
      "count": 56
    },
    {
      "term": "PYREXIA",
      "count": 52
    },
    {
      "term": "MUSCLE HAEMORRHAGE",
      "count": 48
    },
    {
      "term": "OFF LABEL USE",
      "count": 48
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 46
    },
    {
      "term": "EPISTAXIS",
      "count": 44
    },
    {
      "term": "ACQUIRED IMMUNODEFICIENCY SYNDROME",
      "count": 42
    },
    {
      "term": "PAIN",
      "count": 41
    },
    {
      "term": "LIMB INJURY",
      "count": 36
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 34
    },
    {
      "term": "HEADACHE",
      "count": 32
    },
    {
      "term": "NO ADVERSE EVENT",
      "count": 32
    },
    {
      "term": "HAEMOPHILIC ARTHROPATHY",
      "count": 30
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 30
    },
    {
      "term": "JOINT SWELLING",
      "count": 30
    },
    {
      "term": "HEAD INJURY",
      "count": 28
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 26
    },
    {
      "term": "URTICARIA",
      "count": 26
    },
    {
      "term": "ARTHROPATHY",
      "count": 25
    },
    {
      "term": "BACK PAIN",
      "count": 25
    },
    {
      "term": "HYPOTENSION",
      "count": 25
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 24
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 24
    },
    {
      "term": "JOINT INJURY",
      "count": 24
    },
    {
      "term": "PNEUMONIA",
      "count": 24
    },
    {
      "term": "VOMITING",
      "count": 23
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 22
    },
    {
      "term": "COVID-19",
      "count": 22
    },
    {
      "term": "POOR VENOUS ACCESS",
      "count": 22
    },
    {
      "term": "TACHYCARDIA",
      "count": 22
    },
    {
      "term": "DYSPNOEA",
      "count": 21
    },
    {
      "term": "GINGIVAL BLEEDING",
      "count": 21
    },
    {
      "term": "SHOCK HAEMORRHAGIC",
      "count": 21
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 20
    },
    {
      "term": "HIV TEST POSITIVE",
      "count": 20
    },
    {
      "term": "TREATMENT NONCOMPLIANCE",
      "count": 20
    },
    {
      "term": "CENTRAL VENOUS CATHETERISATION",
      "count": 19
    },
    {
      "term": "DEATH",
      "count": 19
    },
    {
      "term": "INJURY",
      "count": 19
    },
    {
      "term": "MALAISE",
      "count": 19
    },
    {
      "term": "INCORRECT DOSE ADMINISTERED",
      "count": 18
    },
    {
      "term": "SEPSIS",
      "count": 18
    },
    {
      "term": "SPONTANEOUS HAEMORRHAGE",
      "count": 18
    },
    {
      "term": "DIARRHOEA",
      "count": 17
    },
    {
      "term": "FACE OEDEMA",
      "count": 17
    },
    {
      "term": "FLATULENCE",
      "count": 17
    },
    {
      "term": "ANAPHYLACTIC SHOCK",
      "count": 16
    },
    {
      "term": "EMPHYSEMA",
      "count": 16
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 16
    },
    {
      "term": "MOUTH HAEMORRHAGE",
      "count": 16
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 16
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 16
    },
    {
      "term": "PNEUMOTHORAX",
      "count": 16
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 16
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 15
    },
    {
      "term": "HAEMATURIA",
      "count": 15
    },
    {
      "term": "HAEMOTHORAX",
      "count": 15
    },
    {
      "term": "HYPOVOLAEMIA",
      "count": 15
    },
    {
      "term": "INSPIRATORY CAPACITY DECREASED",
      "count": 15
    },
    {
      "term": "INSURANCE ISSUE",
      "count": 15
    },
    {
      "term": "POST PROCEDURAL HAEMORRHAGE",
      "count": 15
    },
    {
      "term": "TRAUMATIC HAEMATOMA",
      "count": 15
    },
    {
      "term": "ADVERSE REACTION",
      "count": 14
    },
    {
      "term": "ANGIOPATHY",
      "count": 14
    },
    {
      "term": "COUGH",
      "count": 14
    },
    {
      "term": "DIZZINESS",
      "count": 14
    },
    {
      "term": "HOSPITALISATION",
      "count": 14
    },
    {
      "term": "MECHANICAL VENTILATION COMPLICATION",
      "count": 14
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 14
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 14
    },
    {
      "term": "PRURITUS",
      "count": 14
    },
    {
      "term": "RASH",
      "count": 14
    },
    {
      "term": "FATIGUE",
      "count": 13
    },
    {
      "term": "THROMBOSIS",
      "count": 13
    },
    {
      "term": "ANAEMIA",
      "count": 12
    },
    {
      "term": "ASTHENIA",
      "count": 12
    },
    {
      "term": "CARDIAC ARREST",
      "count": 12
    },
    {
      "term": "CHEST PAIN",
      "count": 12
    },
    {
      "term": "EXTRA DOSE ADMINISTERED",
      "count": 12
    },
    {
      "term": "PRODUCT AVAILABILITY ISSUE",
      "count": 12
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 12
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 11
    },
    {
      "term": "ANTI FACTOR VIII ANTIBODY INCREASED",
      "count": 11
    },
    {
      "term": "BLOOD PRESSURE DECREASED",
      "count": 11
    },
    {
      "term": "NAUSEA",
      "count": 11
    },
    {
      "term": "OEDEMA",
      "count": 11
    },
    {
      "term": "SOMNOLENCE",
      "count": 11
    }
  ]
}