{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 142
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 103
    },
    {
      "term": "CONSTIPATION",
      "count": 90
    },
    {
      "term": "PAIN",
      "count": 78
    },
    {
      "term": "DYSPNOEA",
      "count": 71
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 69
    },
    {
      "term": "NAUSEA",
      "count": 64
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 60
    },
    {
      "term": "ANAEMIA",
      "count": 59
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 58
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 57
    },
    {
      "term": "STRESS",
      "count": 53
    },
    {
      "term": "VOMITING",
      "count": 53
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 52
    },
    {
      "term": "SEPSIS",
      "count": 52
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 51
    },
    {
      "term": "SOMNOLENCE",
      "count": 49
    },
    {
      "term": "DIABETES MELLITUS",
      "count": 46
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 46
    },
    {
      "term": "ORTHOSTATIC HYPOTENSION",
      "count": 46
    },
    {
      "term": "DRUG INTERACTION",
      "count": 45
    },
    {
      "term": "INTENTIONAL PRODUCT MISUSE",
      "count": 45
    },
    {
      "term": "COGNITIVE DISORDER",
      "count": 44
    },
    {
      "term": "NEURALGIA",
      "count": 44
    },
    {
      "term": "SWELLING",
      "count": 44
    },
    {
      "term": "THROMBOSIS",
      "count": 44
    },
    {
      "term": "ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED",
      "count": 43
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 43
    },
    {
      "term": "BALANCE DISORDER",
      "count": 43
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 43
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 43
    },
    {
      "term": "FALL",
      "count": 43
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 43
    },
    {
      "term": "MYASTHENIA GRAVIS",
      "count": 43
    },
    {
      "term": "SEDATION COMPLICATION",
      "count": 43
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 42
    },
    {
      "term": "BLOOD CALCIUM DECREASED",
      "count": 42
    },
    {
      "term": "CHRONIC OBSTRUCTIVE PULMONARY DISEASE",
      "count": 42
    },
    {
      "term": "CREATININE RENAL CLEARANCE DECREASED",
      "count": 42
    },
    {
      "term": "HYPOTENSION",
      "count": 42
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 42
    },
    {
      "term": "SEDATION",
      "count": 42
    },
    {
      "term": "SLEEP DISORDER",
      "count": 42
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 42
    },
    {
      "term": "APPENDICITIS",
      "count": 40
    },
    {
      "term": "ASCITES",
      "count": 40
    },
    {
      "term": "HYPERPHOSPHATAEMIA",
      "count": 40
    },
    {
      "term": "INCORRECT ROUTE OF PRODUCT ADMINISTRATION",
      "count": 40
    },
    {
      "term": "PYREXIA",
      "count": 40
    },
    {
      "term": "APPENDICOLITH",
      "count": 39
    },
    {
      "term": "CARDIOGENIC SHOCK",
      "count": 39
    },
    {
      "term": "HYPOPHOSPHATAEMIA",
      "count": 38
    },
    {
      "term": "OVERDOSE",
      "count": 38
    },
    {
      "term": "RENAL FUNCTION TEST ABNORMAL",
      "count": 38
    },
    {
      "term": "HEADACHE",
      "count": 37
    },
    {
      "term": "ANALGESIC THERAPY",
      "count": 36
    },
    {
      "term": "ASTHENIA",
      "count": 36
    },
    {
      "term": "DRUG ABUSE",
      "count": 36
    },
    {
      "term": "DRUG THERAPY",
      "count": 36
    },
    {
      "term": "DRY MOUTH",
      "count": 35
    },
    {
      "term": "HYPERTENSION",
      "count": 35
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 34
    },
    {
      "term": "BLOOD PHOSPHORUS INCREASED",
      "count": 34
    },
    {
      "term": "END STAGE RENAL DISEASE",
      "count": 34
    },
    {
      "term": "FATIGUE",
      "count": 34
    },
    {
      "term": "GOUT",
      "count": 34
    },
    {
      "term": "SLEEP DISORDER THERAPY",
      "count": 34
    },
    {
      "term": "ULCER",
      "count": 34
    },
    {
      "term": "VENTRICULAR FIBRILLATION",
      "count": 34
    },
    {
      "term": "HYPERLIPIDAEMIA",
      "count": 33
    },
    {
      "term": "TROPONIN INCREASED",
      "count": 33
    },
    {
      "term": "ANTICOAGULANT THERAPY",
      "count": 32
    },
    {
      "term": "BLOOD URIC ACID INCREASED",
      "count": 32
    },
    {
      "term": "CREATININE RENAL CLEARANCE INCREASED",
      "count": 32
    },
    {
      "term": "ANTACID THERAPY",
      "count": 31
    },
    {
      "term": "CONGENITAL HIATUS HERNIA",
      "count": 29
    },
    {
      "term": "IRON DEFICIENCY",
      "count": 27
    },
    {
      "term": "MULTIPLE DRUG THERAPY",
      "count": 26
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 25
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 25
    },
    {
      "term": "TREMOR",
      "count": 24
    },
    {
      "term": "UPPER RESPIRATORY TRACT INFECTION",
      "count": 24
    },
    {
      "term": "ASPIRATION",
      "count": 23
    },
    {
      "term": "ASTHMA",
      "count": 23
    },
    {
      "term": "BENIGN PROSTATIC HYPERPLASIA",
      "count": 23
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS ALLERGIC",
      "count": 23
    },
    {
      "term": "CORONARY ARTERY DISEASE",
      "count": 23
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 23
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 23
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 23
    },
    {
      "term": "AORTIC STENOSIS",
      "count": 22
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 22
    },
    {
      "term": "JOINT INJURY",
      "count": 22
    },
    {
      "term": "MALIGNANT MELANOMA STAGE 0",
      "count": 22
    },
    {
      "term": "MICTURITION URGENCY",
      "count": 22
    },
    {
      "term": "BREATH SOUNDS ABNORMAL",
      "count": 21
    },
    {
      "term": "FULL BLOOD COUNT ABNORMAL",
      "count": 21
    },
    {
      "term": "PLEURITIC PAIN",
      "count": 21
    },
    {
      "term": "BLOOD CALCIUM INCREASED",
      "count": 20
    },
    {
      "term": "BLOOD TEST ABNORMAL",
      "count": 20
    }
  ]
}