{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1464
    },
    {
      "term": "OFF LABEL USE",
      "count": 1135
    },
    {
      "term": "PYREXIA",
      "count": 680
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 591
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 556
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 544
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 540
    },
    {
      "term": "NAUSEA",
      "count": 520
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 500
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 474
    },
    {
      "term": "PNEUMONIA",
      "count": 447
    },
    {
      "term": "DIARRHOEA",
      "count": 426
    },
    {
      "term": "SEPSIS",
      "count": 409
    },
    {
      "term": "DYSPNOEA",
      "count": 407
    },
    {
      "term": "VOMITING",
      "count": 401
    },
    {
      "term": "ANAEMIA",
      "count": 377
    },
    {
      "term": "DRUG INTERACTION",
      "count": 369
    },
    {
      "term": "NEUTROPENIA",
      "count": 350
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 331
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 291
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 285
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 280
    },
    {
      "term": "RASH",
      "count": 280
    },
    {
      "term": "COUGH",
      "count": 276
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 271
    },
    {
      "term": "RENAL FAILURE",
      "count": 267
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 252
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 252
    },
    {
      "term": "PANCYTOPENIA",
      "count": 250
    },
    {
      "term": "DEAFNESS",
      "count": 243
    },
    {
      "term": "DEATH",
      "count": 235
    },
    {
      "term": "HYPOTENSION",
      "count": 234
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 223
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 219
    },
    {
      "term": "OTOTOXICITY",
      "count": 197
    },
    {
      "term": "LEUKOPENIA",
      "count": 196
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 196
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 194
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 192
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 190
    },
    {
      "term": "ASTHENIA",
      "count": 189
    },
    {
      "term": "MYCOBACTERIUM AVIUM COMPLEX INFECTION",
      "count": 174
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 170
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 163
    },
    {
      "term": "FATIGUE",
      "count": 162
    },
    {
      "term": "PSEUDOMONAS INFECTION",
      "count": 162
    },
    {
      "term": "EOSINOPHILIA",
      "count": 160
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 160
    },
    {
      "term": "TACHYCARDIA",
      "count": 158
    },
    {
      "term": "INFECTION",
      "count": 157
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 156
    },
    {
      "term": "CANDIDA INFECTION",
      "count": 153
    },
    {
      "term": "PRURITUS",
      "count": 152
    },
    {
      "term": "CARDIAC ARREST",
      "count": 148
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 148
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 148
    },
    {
      "term": "TINNITUS",
      "count": 147
    },
    {
      "term": "DECREASED APPETITE",
      "count": 146
    },
    {
      "term": "MYCOBACTERIUM ABSCESSUS INFECTION",
      "count": 146
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 145
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 143
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 141
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 140
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 137
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 137
    },
    {
      "term": "MALAISE",
      "count": 135
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 135
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 134
    },
    {
      "term": "HEADACHE",
      "count": 131
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 128
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 128
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 122
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 121
    },
    {
      "term": "DIZZINESS",
      "count": 118
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 118
    },
    {
      "term": "HAEMOPTYSIS",
      "count": 115
    },
    {
      "term": "KLEBSIELLA INFECTION",
      "count": 115
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 115
    },
    {
      "term": "LUNG DISORDER",
      "count": 114
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 112
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 110
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 106
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 104
    },
    {
      "term": "IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME",
      "count": 104
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 103
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 103
    },
    {
      "term": "ERYTHEMA",
      "count": 101
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE COLITIS",
      "count": 100
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 100
    },
    {
      "term": "ENTEROCOCCAL INFECTION",
      "count": 99
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 98
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 97
    },
    {
      "term": "ARTHRALGIA",
      "count": 96
    },
    {
      "term": "COMA",
      "count": 96
    },
    {
      "term": "PAIN",
      "count": 95
    },
    {
      "term": "CHOLESTASIS",
      "count": 94
    },
    {
      "term": "TOXIC SKIN ERUPTION",
      "count": 94
    },
    {
      "term": "DEAFNESS NEUROSENSORY",
      "count": 92
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 91
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 91
    }
  ]
}