{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "HYPERGLYCAEMIA",
      "count": 327
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 237
    },
    {
      "term": "RASH",
      "count": 191
    },
    {
      "term": "DIARRHOEA",
      "count": 152
    },
    {
      "term": "DEATH",
      "count": 110
    },
    {
      "term": "FATIGUE",
      "count": 104
    },
    {
      "term": "BREAST CANCER METASTATIC",
      "count": 103
    },
    {
      "term": "NAUSEA",
      "count": 103
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 100
    },
    {
      "term": "METASTASES TO BONE",
      "count": 90
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 85
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 77
    },
    {
      "term": "DECREASED APPETITE",
      "count": 76
    },
    {
      "term": "DIABETES MELLITUS",
      "count": 74
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 71
    },
    {
      "term": "VOMITING",
      "count": 64
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 61
    },
    {
      "term": "OFF LABEL USE",
      "count": 59
    },
    {
      "term": "PYREXIA",
      "count": 54
    },
    {
      "term": "BREAST CANCER",
      "count": 51
    },
    {
      "term": "ASTHENIA",
      "count": 50
    },
    {
      "term": "PNEUMONIA",
      "count": 49
    },
    {
      "term": "DIABETIC KETOACIDOSIS",
      "count": 47
    },
    {
      "term": "PRURITUS",
      "count": 43
    },
    {
      "term": "NEUTROPENIA",
      "count": 41
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 39
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 36
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 33
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 32
    },
    {
      "term": "PAIN",
      "count": 31
    },
    {
      "term": "DYSPNOEA",
      "count": 30
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 30
    },
    {
      "term": "COVID-19",
      "count": 29
    },
    {
      "term": "HEADACHE",
      "count": 29
    },
    {
      "term": "HYPOGLYCAEMIA",
      "count": 28
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 26
    },
    {
      "term": "PIK3CA-ACTIVATED MUTATION",
      "count": 26
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 26
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 26
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 24
    },
    {
      "term": "DEHYDRATION",
      "count": 24
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 23
    },
    {
      "term": "COLITIS",
      "count": 23
    },
    {
      "term": "DRY MOUTH",
      "count": 23
    },
    {
      "term": "PNEUMONITIS",
      "count": 21
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 20
    },
    {
      "term": "MALAISE",
      "count": 20
    },
    {
      "term": "ANAEMIA",
      "count": 19
    },
    {
      "term": "ASCITES",
      "count": 19
    },
    {
      "term": "METASTASES TO CENTRAL NERVOUS SYSTEM",
      "count": 19
    },
    {
      "term": "METASTASES TO LYMPH NODES",
      "count": 19
    },
    {
      "term": "METASTASES TO PLEURA",
      "count": 19
    },
    {
      "term": "URTICARIA",
      "count": 19
    },
    {
      "term": "OSTEONECROSIS OF JAW",
      "count": 18
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 18
    },
    {
      "term": "SKIN TOXICITY",
      "count": 18
    },
    {
      "term": "ERYTHEMA",
      "count": 17
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 17
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 17
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 17
    },
    {
      "term": "BACK PAIN",
      "count": 16
    },
    {
      "term": "COUGH",
      "count": 16
    },
    {
      "term": "DIZZINESS",
      "count": 16
    },
    {
      "term": "POLYDIPSIA",
      "count": 16
    },
    {
      "term": "STOMATITIS",
      "count": 16
    },
    {
      "term": "ANXIETY",
      "count": 15
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 15
    },
    {
      "term": "BONE LESION",
      "count": 14
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 13
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 13
    },
    {
      "term": "TUMOUR MARKER INCREASED",
      "count": 13
    },
    {
      "term": "ALOPECIA",
      "count": 12
    },
    {
      "term": "GLYCOSYLATED HAEMOGLOBIN INCREASED",
      "count": 12
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 12
    },
    {
      "term": "LYMPHADENOPATHY",
      "count": 12
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 12
    },
    {
      "term": "POLYURIA",
      "count": 12
    },
    {
      "term": "TRANSAMINASES INCREASED",
      "count": 12
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 12
    },
    {
      "term": "POISONING",
      "count": 11
    },
    {
      "term": "RASH MACULAR",
      "count": 11
    },
    {
      "term": "AGITATION",
      "count": 10
    },
    {
      "term": "ARTHRALGIA",
      "count": 10
    },
    {
      "term": "CARBOHYDRATE ANTIGEN 15-3 INCREASED",
      "count": 10
    },
    {
      "term": "HYPERGLYCAEMIC HYPEROSMOLAR NONKETOTIC SYNDROME",
      "count": 10
    },
    {
      "term": "MENTAL IMPAIRMENT",
      "count": 10
    },
    {
      "term": "METASTASES TO PERITONEUM",
      "count": 10
    },
    {
      "term": "OEDEMA",
      "count": 10
    },
    {
      "term": "PSYCHIATRIC DECOMPENSATION",
      "count": 10
    },
    {
      "term": "RASH PRURITIC",
      "count": 10
    },
    {
      "term": "RENAL FAILURE",
      "count": 10
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 10
    },
    {
      "term": "SUICIDE ATTEMPT",
      "count": 10
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 9
    },
    {
      "term": "CHILLS",
      "count": 9
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 9
    },
    {
      "term": "DYSPHAGIA",
      "count": 9
    },
    {
      "term": "FACE OEDEMA",
      "count": 9
    },
    {
      "term": "HORMONE RECEPTOR POSITIVE HER2 NEGATIVE BREAST CANCER",
      "count": 9
    },
    {
      "term": "KETOACIDOSIS",
      "count": 9
    }
  ]
}