{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "RENAL FAILURE",
      "count": 398
    },
    {
      "term": "OFF LABEL USE",
      "count": 362
    },
    {
      "term": "PYREXIA",
      "count": 332
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 323
    },
    {
      "term": "PAIN",
      "count": 323
    },
    {
      "term": "DYSPNOEA",
      "count": 287
    },
    {
      "term": "PNEUMONIA",
      "count": 281
    },
    {
      "term": "INJURY",
      "count": 272
    },
    {
      "term": "ANXIETY",
      "count": 265
    },
    {
      "term": "HYPOTENSION",
      "count": 259
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 258
    },
    {
      "term": "UNEVALUABLE EVENT",
      "count": 252
    },
    {
      "term": "SEPSIS",
      "count": 232
    },
    {
      "term": "DEATH",
      "count": 226
    },
    {
      "term": "FEAR",
      "count": 223
    },
    {
      "term": "RENAL INJURY",
      "count": 202
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 200
    },
    {
      "term": "ANAEMIA",
      "count": 196
    },
    {
      "term": "DIARRHOEA",
      "count": 194
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 190
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 182
    },
    {
      "term": "STRESS",
      "count": 176
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 160
    },
    {
      "term": "ANHEDONIA",
      "count": 158
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 155
    },
    {
      "term": "NAUSEA",
      "count": 150
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 144
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 140
    },
    {
      "term": "RASH",
      "count": 137
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 136
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 130
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 128
    },
    {
      "term": "ASCITES",
      "count": 125
    },
    {
      "term": "PULMONARY OEDEMA",
      "count": 119
    },
    {
      "term": "PRURITUS",
      "count": 114
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 113
    },
    {
      "term": "CHILLS",
      "count": 110
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 108
    },
    {
      "term": "HYPOXIA",
      "count": 108
    },
    {
      "term": "VOMITING",
      "count": 107
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 104
    },
    {
      "term": "COUGH",
      "count": 103
    },
    {
      "term": "FATIGUE",
      "count": 103
    },
    {
      "term": "CARDIAC ARREST",
      "count": 101
    },
    {
      "term": "DEPRESSION",
      "count": 101
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 101
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 96
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 96
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 93
    },
    {
      "term": "HYPERTENSION",
      "count": 93
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 92
    },
    {
      "term": "TACHYCARDIA",
      "count": 91
    },
    {
      "term": "HYPOALBUMINAEMIA",
      "count": 90
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 90
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 87
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 86
    },
    {
      "term": "NEUTROPENIA",
      "count": 86
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 84
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 83
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 83
    },
    {
      "term": "ASTHENIA",
      "count": 83
    },
    {
      "term": "BLOOD PRESSURE DECREASED",
      "count": 78
    },
    {
      "term": "INFECTION",
      "count": 78
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 77
    },
    {
      "term": "URTICARIA",
      "count": 77
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 76
    },
    {
      "term": "STEVENS-JOHNSON SYNDROME",
      "count": 75
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 74
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 74
    },
    {
      "term": "PANCYTOPENIA",
      "count": 73
    },
    {
      "term": "DISSEMINATED INTRAVASCULAR COAGULATION",
      "count": 72
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 72
    },
    {
      "term": "ERYTHEMA",
      "count": 71
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 70
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 69
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 69
    },
    {
      "term": "TACHYPNOEA",
      "count": 69
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 68
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 68
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 68
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 68
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 68
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 67
    },
    {
      "term": "SHOCK",
      "count": 67
    },
    {
      "term": "ACUTE RESPIRATORY FAILURE",
      "count": 66
    },
    {
      "term": "FALL",
      "count": 66
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 63
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 63
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 62
    },
    {
      "term": "DRUG INTERACTION",
      "count": 61
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 61
    },
    {
      "term": "ANAPHYLACTIC SHOCK",
      "count": 60
    },
    {
      "term": "LEUKOPENIA",
      "count": 59
    },
    {
      "term": "DIZZINESS",
      "count": 57
    },
    {
      "term": "CHEST PAIN",
      "count": 55
    },
    {
      "term": "DECREASED APPETITE",
      "count": 55
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 55
    },
    {
      "term": "BLOOD UREA INCREASED",
      "count": 53
    },
    {
      "term": "GENERALISED OEDEMA",
      "count": 52
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 51
    }
  ]
}