{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 383
    },
    {
      "term": "OFF LABEL USE",
      "count": 137
    },
    {
      "term": "SUPRAVENTRICULAR TACHYCARDIA",
      "count": 112
    },
    {
      "term": "HYPOTENSION",
      "count": 99
    },
    {
      "term": "DYSPNOEA",
      "count": 94
    },
    {
      "term": "PAIN",
      "count": 93
    },
    {
      "term": "CARDIAC ARREST",
      "count": 85
    },
    {
      "term": "NAUSEA",
      "count": 83
    },
    {
      "term": "ANXIETY",
      "count": 76
    },
    {
      "term": "BRADYCARDIA",
      "count": 72
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 72
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 70
    },
    {
      "term": "DIZZINESS",
      "count": 66
    },
    {
      "term": "PNEUMONIA",
      "count": 66
    },
    {
      "term": "TACHYCARDIA",
      "count": 65
    },
    {
      "term": "DRUG INTERACTION",
      "count": 64
    },
    {
      "term": "FATIGUE",
      "count": 60
    },
    {
      "term": "VENTRICULAR TACHYCARDIA",
      "count": 57
    },
    {
      "term": "PYREXIA",
      "count": 52
    },
    {
      "term": "BRONCHOSPASM",
      "count": 51
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 50
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 49
    },
    {
      "term": "DIARRHOEA",
      "count": 49
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 48
    },
    {
      "term": "HYPERTENSION",
      "count": 48
    },
    {
      "term": "VENTRICULAR FIBRILLATION",
      "count": 48
    },
    {
      "term": "RENAL FAILURE",
      "count": 47
    },
    {
      "term": "ASTHENIA",
      "count": 45
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 45
    },
    {
      "term": "ANHEDONIA",
      "count": 43
    },
    {
      "term": "VOMITING",
      "count": 43
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 42
    },
    {
      "term": "HEADACHE",
      "count": 42
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 41
    },
    {
      "term": "MALAISE",
      "count": 40
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 39
    },
    {
      "term": "CHEST PAIN",
      "count": 37
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 36
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 36
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 35
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 35
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 34
    },
    {
      "term": "ANAEMIA",
      "count": 34
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 32
    },
    {
      "term": "RASH",
      "count": 32
    },
    {
      "term": "PRURITUS",
      "count": 31
    },
    {
      "term": "ARTERIOSPASM CORONARY",
      "count": 30
    },
    {
      "term": "CARDIOGENIC SHOCK",
      "count": 30
    },
    {
      "term": "DECREASED APPETITE",
      "count": 30
    },
    {
      "term": "DEPRESSION",
      "count": 30
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 30
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 29
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 29
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 29
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 29
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 28
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 28
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 28
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 28
    },
    {
      "term": "ARRHYTHMIA",
      "count": 27
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 27
    },
    {
      "term": "ATRIOVENTRICULAR BLOCK",
      "count": 27
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 27
    },
    {
      "term": "LIVER FUNCTION TEST ABNORMAL",
      "count": 27
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 27
    },
    {
      "term": "PALPITATIONS",
      "count": 27
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 26
    },
    {
      "term": "COUGH",
      "count": 26
    },
    {
      "term": "ECONOMIC PROBLEM",
      "count": 26
    },
    {
      "term": "HYPOXIA",
      "count": 26
    },
    {
      "term": "INJURY",
      "count": 26
    },
    {
      "term": "METABOLIC ACIDOSIS",
      "count": 26
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 26
    },
    {
      "term": "FALL",
      "count": 25
    },
    {
      "term": "OVERDOSE",
      "count": 25
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 25
    },
    {
      "term": "SEPSIS",
      "count": 25
    },
    {
      "term": "ACUTE MYOCARDIAL INFARCTION",
      "count": 24
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 24
    },
    {
      "term": "CIRCULATORY COLLAPSE",
      "count": 24
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 24
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 23
    },
    {
      "term": "MYOSITIS",
      "count": 23
    },
    {
      "term": "PREMATURE BABY",
      "count": 23
    },
    {
      "term": "ATRIOVENTRICULAR BLOCK COMPLETE",
      "count": 22
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 22
    },
    {
      "term": "HEART RATE INCREASED",
      "count": 22
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 22
    },
    {
      "term": "BACK PAIN",
      "count": 21
    },
    {
      "term": "DEATH",
      "count": 21
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 21
    },
    {
      "term": "INFECTION",
      "count": 21
    },
    {
      "term": "OSTEOPOROSIS",
      "count": 21
    },
    {
      "term": "PERICARDIAL EFFUSION",
      "count": 21
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 21
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 21
    },
    {
      "term": "BLOOD PRESSURE DECREASED",
      "count": 20
    },
    {
      "term": "COVID-19",
      "count": 20
    },
    {
      "term": "HAEMODYNAMIC INSTABILITY",
      "count": 20
    },
    {
      "term": "HYPOGLYCAEMIA",
      "count": 20
    }
  ]
}