{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 10152
    },
    {
      "term": "OFF LABEL USE",
      "count": 7966
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 5494
    },
    {
      "term": "PAIN",
      "count": 5295
    },
    {
      "term": "FATIGUE",
      "count": 5290
    },
    {
      "term": "ARTHRALGIA",
      "count": 5019
    },
    {
      "term": "RASH",
      "count": 4502
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 4314
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 4158
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 4007
    },
    {
      "term": "NAUSEA",
      "count": 3937
    },
    {
      "term": "JOINT SWELLING",
      "count": 3929
    },
    {
      "term": "HEADACHE",
      "count": 3910
    },
    {
      "term": "DIARRHOEA",
      "count": 3886
    },
    {
      "term": "ALOPECIA",
      "count": 3789
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 3754
    },
    {
      "term": "SYNOVITIS",
      "count": 3752
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 3737
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 3636
    },
    {
      "term": "ARTHROPATHY",
      "count": 3567
    },
    {
      "term": "GLOSSODYNIA",
      "count": 3552
    },
    {
      "term": "PEMPHIGUS",
      "count": 3450
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 3431
    },
    {
      "term": "MALAISE",
      "count": 3404
    },
    {
      "term": "SWELLING",
      "count": 3344
    },
    {
      "term": "HAND DEFORMITY",
      "count": 3302
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 3266
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 3219
    },
    {
      "term": "VOMITING",
      "count": 3216
    },
    {
      "term": "WOUND",
      "count": 3204
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 3203
    },
    {
      "term": "HYPERTENSION",
      "count": 3165
    },
    {
      "term": "PYREXIA",
      "count": 3078
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 3017
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 2985
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 2953
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 2943
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 2940
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 2882
    },
    {
      "term": "INFECTION",
      "count": 2868
    },
    {
      "term": "PERICARDITIS",
      "count": 2810
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 2788
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 2771
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 2696
    },
    {
      "term": "DIZZINESS",
      "count": 2692
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 2636
    },
    {
      "term": "CROHN^S DISEASE",
      "count": 2632
    },
    {
      "term": "PNEUMONIA",
      "count": 2619
    },
    {
      "term": "HELICOBACTER INFECTION",
      "count": 2606
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 2592
    },
    {
      "term": "FIBROMYALGIA",
      "count": 2587
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 2567
    },
    {
      "term": "DYSPNOEA",
      "count": 2555
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 2534
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 2523
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 2438
    },
    {
      "term": "DISCOMFORT",
      "count": 2415
    },
    {
      "term": "FOLLICULITIS",
      "count": 2409
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 2393
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 2347
    },
    {
      "term": "INJURY",
      "count": 2336
    },
    {
      "term": "URTICARIA",
      "count": 2329
    },
    {
      "term": "BLISTER",
      "count": 2327
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 2303
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 2258
    },
    {
      "term": "LIVER INJURY",
      "count": 2257
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 2255
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 2240
    },
    {
      "term": "PRURITUS",
      "count": 2234
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 2223
    },
    {
      "term": "INFLAMMATION",
      "count": 2216
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 2203
    },
    {
      "term": "ASTHENIA",
      "count": 2199
    },
    {
      "term": "DECREASED APPETITE",
      "count": 2185
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 2122
    },
    {
      "term": "WHEEZING",
      "count": 2108
    },
    {
      "term": "INSOMNIA",
      "count": 2099
    },
    {
      "term": "STOMATITIS",
      "count": 2098
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 2079
    },
    {
      "term": "RHEUMATOID FACTOR POSITIVE",
      "count": 2074
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 2012
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 1991
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 1924
    },
    {
      "term": "DEPRESSION",
      "count": 1923
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 1920
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 1895
    },
    {
      "term": "ARTHRITIS",
      "count": 1892
    },
    {
      "term": "JOINT RANGE OF MOTION DECREASED",
      "count": 1878
    },
    {
      "term": "PSORIASIS",
      "count": 1877
    },
    {
      "term": "MUSCLE INJURY",
      "count": 1866
    },
    {
      "term": "SLEEP DISORDER",
      "count": 1828
    },
    {
      "term": "SINUSITIS",
      "count": 1773
    },
    {
      "term": "C-REACTIVE PROTEIN ABNORMAL",
      "count": 1712
    },
    {
      "term": "GAIT INABILITY",
      "count": 1676
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 1676
    },
    {
      "term": "DYSPEPSIA",
      "count": 1675
    },
    {
      "term": "DRY MOUTH",
      "count": 1665
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 1629
    },
    {
      "term": "BURSITIS",
      "count": 1616
    },
    {
      "term": "OEDEMA",
      "count": 1569
    }
  ]
}