{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INTERACTION",
      "count": 15
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 12
    },
    {
      "term": "RENAL FAILURE",
      "count": 11
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 10
    },
    {
      "term": "OFF LABEL USE",
      "count": 10
    },
    {
      "term": "NAUSEA",
      "count": 9
    },
    {
      "term": "UNRESPONSIVE TO STIMULI",
      "count": 9
    },
    {
      "term": "VOMITING",
      "count": 9
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 8
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 7
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 7
    },
    {
      "term": "DIARRHOEA",
      "count": 7
    },
    {
      "term": "HYPOXIA",
      "count": 7
    },
    {
      "term": "RESPIRATORY DEPRESSION",
      "count": 7
    },
    {
      "term": "HYPERTENSION",
      "count": 6
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 6
    },
    {
      "term": "OVERDOSE",
      "count": 6
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 5
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 5
    },
    {
      "term": "DEATH",
      "count": 5
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 5
    },
    {
      "term": "ASTHENIA",
      "count": 4
    },
    {
      "term": "CONSTIPATION",
      "count": 4
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 4
    },
    {
      "term": "GAMMA-GLUTAMYLTRANSFERASE INCREASED",
      "count": 4
    },
    {
      "term": "LIVER FUNCTION TEST INCREASED",
      "count": 4
    },
    {
      "term": "MIXED LIVER INJURY",
      "count": 4
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 4
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 4
    },
    {
      "term": "PERICARDIAL EFFUSION",
      "count": 4
    },
    {
      "term": "PYREXIA",
      "count": 4
    },
    {
      "term": "SOMNOLENCE",
      "count": 4
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 4
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 4
    },
    {
      "term": "BLOOD ALKALINE PHOSPHATASE INCREASED",
      "count": 3
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 3
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 3
    },
    {
      "term": "DIZZINESS",
      "count": 3
    },
    {
      "term": "DRUG LEVEL INCREASED",
      "count": 3
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 3
    },
    {
      "term": "HEPATIC CYTOLYSIS",
      "count": 3
    },
    {
      "term": "MENTAL STATUS CHANGES",
      "count": 3
    },
    {
      "term": "SEIZURE",
      "count": 3
    },
    {
      "term": "SEPSIS",
      "count": 3
    },
    {
      "term": "STATUS EPILEPTICUS",
      "count": 3
    },
    {
      "term": "ANAEMIA",
      "count": 2
    },
    {
      "term": "CHEST PAIN",
      "count": 2
    },
    {
      "term": "COVID-19",
      "count": 2
    },
    {
      "term": "DEHYDRATION",
      "count": 2
    },
    {
      "term": "EJECTION FRACTION DECREASED",
      "count": 2
    },
    {
      "term": "EOSINOPHILIA",
      "count": 2
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 2
    },
    {
      "term": "HYPOTENSION",
      "count": 2
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 2
    },
    {
      "term": "METABOLIC ACIDOSIS",
      "count": 2
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 2
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 2
    },
    {
      "term": "RASH",
      "count": 2
    },
    {
      "term": "RASH MACULAR",
      "count": 2
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 2
    },
    {
      "term": "TENDON RUPTURE",
      "count": 2
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 2
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 1
    },
    {
      "term": "ABDOMINAL PAIN LOWER",
      "count": 1
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 1
    },
    {
      "term": "ABDOMINAL WALL ABSCESS",
      "count": 1
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 1
    },
    {
      "term": "ADENOVIRUS TEST POSITIVE",
      "count": 1
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 1
    },
    {
      "term": "AMYLASE INCREASED",
      "count": 1
    },
    {
      "term": "ARTHRALGIA",
      "count": 1
    },
    {
      "term": "ASCITES",
      "count": 1
    },
    {
      "term": "ATRIAL FLUTTER",
      "count": 1
    },
    {
      "term": "BACK PAIN",
      "count": 1
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 1
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 1
    },
    {
      "term": "BLOOD GLUCOSE DECREASED",
      "count": 1
    },
    {
      "term": "BRAIN OEDEMA",
      "count": 1
    },
    {
      "term": "BRONCHOPULMONARY DISEASE",
      "count": 1
    },
    {
      "term": "CARDIAC ARREST",
      "count": 1
    },
    {
      "term": "CHILLS",
      "count": 1
    },
    {
      "term": "CHOLECYSTITIS ACUTE",
      "count": 1
    },
    {
      "term": "CHOLESTATIC LIVER INJURY",
      "count": 1
    },
    {
      "term": "COLITIS",
      "count": 1
    },
    {
      "term": "COLORECTAL ADENOCARCINOMA",
      "count": 1
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 1
    },
    {
      "term": "CONJUNCTIVITIS",
      "count": 1
    },
    {
      "term": "DECREASED APPETITE",
      "count": 1
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 1
    },
    {
      "term": "DELIRIUM",
      "count": 1
    },
    {
      "term": "DERMATITIS",
      "count": 1
    },
    {
      "term": "DERMATITIS EXFOLIATIVE GENERALISED",
      "count": 1
    },
    {
      "term": "DIPLOPIA",
      "count": 1
    },
    {
      "term": "DRUG EFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 1
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 1
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 1
    },
    {
      "term": "DRUG SCREEN POSITIVE",
      "count": 1
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 1
    },
    {
      "term": "DYSCHROMATOPSIA",
      "count": 1
    },
    {
      "term": "DYSKINESIA OESOPHAGEAL",
      "count": 1
    }
  ]
}