{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 712
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 689
    },
    {
      "term": "HEADACHE",
      "count": 298
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 294
    },
    {
      "term": "FATIGUE",
      "count": 259
    },
    {
      "term": "NAUSEA",
      "count": 258
    },
    {
      "term": "DYSPNOEA",
      "count": 250
    },
    {
      "term": "METABOLIC ACIDOSIS",
      "count": 209
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 194
    },
    {
      "term": "DIARRHOEA",
      "count": 189
    },
    {
      "term": "VOMITING",
      "count": 176
    },
    {
      "term": "DIZZINESS",
      "count": 168
    },
    {
      "term": "PAIN",
      "count": 166
    },
    {
      "term": "INTRAOCULAR PRESSURE INCREASED",
      "count": 157
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 156
    },
    {
      "term": "SOMNOLENCE",
      "count": 147
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 142
    },
    {
      "term": "ARTHRALGIA",
      "count": 130
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 130
    },
    {
      "term": "FALL",
      "count": 128
    },
    {
      "term": "DRUG INTERACTION",
      "count": 127
    },
    {
      "term": "PYREXIA",
      "count": 126
    },
    {
      "term": "PARAESTHESIA",
      "count": 124
    },
    {
      "term": "ANXIETY",
      "count": 122
    },
    {
      "term": "ASTHENIA",
      "count": 122
    },
    {
      "term": "DEATH",
      "count": 119
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 119
    },
    {
      "term": "HYPOTENSION",
      "count": 116
    },
    {
      "term": "RASH",
      "count": 114
    },
    {
      "term": "VISION BLURRED",
      "count": 111
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 105
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 104
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 104
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 101
    },
    {
      "term": "GLAUCOMA",
      "count": 98
    },
    {
      "term": "BACK PAIN",
      "count": 95
    },
    {
      "term": "DEPRESSION",
      "count": 95
    },
    {
      "term": "PNEUMONIA",
      "count": 95
    },
    {
      "term": "MALAISE",
      "count": 92
    },
    {
      "term": "RENAL FAILURE",
      "count": 92
    },
    {
      "term": "DECREASED APPETITE",
      "count": 91
    },
    {
      "term": "SEIZURE",
      "count": 87
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 86
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 86
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 84
    },
    {
      "term": "INTRACRANIAL PRESSURE INCREASED",
      "count": 84
    },
    {
      "term": "COUGH",
      "count": 80
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 80
    },
    {
      "term": "DEHYDRATION",
      "count": 79
    },
    {
      "term": "ANGLE CLOSURE GLAUCOMA",
      "count": 76
    },
    {
      "term": "EYE PAIN",
      "count": 76
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 75
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 74
    },
    {
      "term": "LUNG DISORDER",
      "count": 74
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 72
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 72
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 72
    },
    {
      "term": "HYPERTENSION",
      "count": 71
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 70
    },
    {
      "term": "INSOMNIA",
      "count": 70
    },
    {
      "term": "CHEST PAIN",
      "count": 69
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 69
    },
    {
      "term": "PAPILLOEDEMA",
      "count": 69
    },
    {
      "term": "CONSTIPATION",
      "count": 68
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 68
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 67
    },
    {
      "term": "MIGRAINE",
      "count": 67
    },
    {
      "term": "ANAEMIA",
      "count": 66
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 65
    },
    {
      "term": "CHOROIDAL EFFUSION",
      "count": 64
    },
    {
      "term": "IDIOPATHIC INTRACRANIAL HYPERTENSION",
      "count": 64
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 64
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 63
    },
    {
      "term": "VISUAL ACUITY REDUCED",
      "count": 63
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 62
    },
    {
      "term": "COVID-19",
      "count": 61
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 61
    },
    {
      "term": "HYPOXIA",
      "count": 61
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 59
    },
    {
      "term": "PRURITUS",
      "count": 59
    },
    {
      "term": "INFECTION",
      "count": 58
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 58
    },
    {
      "term": "CHOROIDAL DETACHMENT",
      "count": 57
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 57
    },
    {
      "term": "SINUSITIS",
      "count": 57
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 55
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 55
    },
    {
      "term": "BLINDNESS",
      "count": 54
    },
    {
      "term": "CATARACT",
      "count": 54
    },
    {
      "term": "CHRONIC OBSTRUCTIVE PULMONARY DISEASE",
      "count": 52
    },
    {
      "term": "ASTHMA",
      "count": 51
    },
    {
      "term": "BALANCE DISORDER",
      "count": 51
    },
    {
      "term": "CARDIAC FAILURE CONGESTIVE",
      "count": 47
    },
    {
      "term": "ACUTE RESPIRATORY FAILURE",
      "count": 45
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 45
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 45
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 45
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 45
    },
    {
      "term": "THROMBOSIS",
      "count": 45
    },
    {
      "term": "PALPITATIONS",
      "count": 44
    }
  ]
}