{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DEPENDENCE",
      "count": 3704
    },
    {
      "term": "OVERDOSE",
      "count": 2149
    },
    {
      "term": "PAIN",
      "count": 2074
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1978
    },
    {
      "term": "FATIGUE",
      "count": 1975
    },
    {
      "term": "ARTHRALGIA",
      "count": 1786
    },
    {
      "term": "RASH",
      "count": 1666
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 1648
    },
    {
      "term": "OFF LABEL USE",
      "count": 1621
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 1607
    },
    {
      "term": "JOINT SWELLING",
      "count": 1573
    },
    {
      "term": "DYSPNOEA",
      "count": 1533
    },
    {
      "term": "BLISTER",
      "count": 1476
    },
    {
      "term": "ALOPECIA",
      "count": 1473
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 1467
    },
    {
      "term": "ARTHROPATHY",
      "count": 1466
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 1466
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 1455
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 1446
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 1442
    },
    {
      "term": "SWELLING",
      "count": 1437
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 1434
    },
    {
      "term": "HELICOBACTER INFECTION",
      "count": 1433
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 1431
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 1428
    },
    {
      "term": "STOMATITIS",
      "count": 1419
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 1417
    },
    {
      "term": "FOLLICULITIS",
      "count": 1414
    },
    {
      "term": "PERICARDITIS",
      "count": 1385
    },
    {
      "term": "PEMPHIGUS",
      "count": 1382
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 1378
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 1372
    },
    {
      "term": "HAND DEFORMITY",
      "count": 1369
    },
    {
      "term": "SYNOVITIS",
      "count": 1366
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 1347
    },
    {
      "term": "GLOSSODYNIA",
      "count": 1339
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 1323
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 1306
    },
    {
      "term": "MUSCLE INJURY",
      "count": 1304
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 1294
    },
    {
      "term": "PYREXIA",
      "count": 1291
    },
    {
      "term": "HEADACHE",
      "count": 1280
    },
    {
      "term": "DIARRHOEA",
      "count": 1266
    },
    {
      "term": "NAUSEA",
      "count": 1258
    },
    {
      "term": "WOUND",
      "count": 1256
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 1217
    },
    {
      "term": "VOMITING",
      "count": 1202
    },
    {
      "term": "INFECTION",
      "count": 1170
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 1164
    },
    {
      "term": "DISCOMFORT",
      "count": 1151
    },
    {
      "term": "DIZZINESS",
      "count": 1132
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 1132
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 1121
    },
    {
      "term": "HYPERTENSION",
      "count": 1113
    },
    {
      "term": "PRURITUS",
      "count": 1111
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 1094
    },
    {
      "term": "DEPRESSION",
      "count": 1090
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 1082
    },
    {
      "term": "MALAISE",
      "count": 1072
    },
    {
      "term": "ASTHENIA",
      "count": 1056
    },
    {
      "term": "CONTUSION",
      "count": 1037
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 1023
    },
    {
      "term": "FIBROMYALGIA",
      "count": 1016
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 1012
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 1002
    },
    {
      "term": "SINUSITIS",
      "count": 998
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 980
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 950
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 949
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 946
    },
    {
      "term": "URTICARIA",
      "count": 946
    },
    {
      "term": "INJURY",
      "count": 924
    },
    {
      "term": "BURSITIS",
      "count": 919
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 914
    },
    {
      "term": "DEATH",
      "count": 903
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 890
    },
    {
      "term": "PNEUMONIA",
      "count": 883
    },
    {
      "term": "WHEEZING",
      "count": 863
    },
    {
      "term": "JOINT RANGE OF MOTION DECREASED",
      "count": 850
    },
    {
      "term": "SLEEP DISORDER",
      "count": 842
    },
    {
      "term": "SLEEP DISORDER DUE TO GENERAL MEDICAL CONDITION, INSOMNIA TYPE",
      "count": 836
    },
    {
      "term": "LIVER INJURY",
      "count": 834
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 826
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 822
    },
    {
      "term": "DRY MOUTH",
      "count": 820
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 801
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 794
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 786
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 776
    },
    {
      "term": "MUSCULOSKELETAL PAIN",
      "count": 762
    },
    {
      "term": "INSOMNIA",
      "count": 757
    },
    {
      "term": "INFLAMMATION",
      "count": 750
    },
    {
      "term": "FACET JOINT SYNDROME",
      "count": 748
    },
    {
      "term": "PARAESTHESIA",
      "count": 747
    },
    {
      "term": "DECREASED APPETITE",
      "count": 743
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 742
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 733
    },
    {
      "term": "ANXIETY",
      "count": 725
    },
    {
      "term": "LIP DRY",
      "count": 701
    },
    {
      "term": "GAIT INABILITY",
      "count": 695
    }
  ]
}