{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG DEPENDENCE",
      "count": 51167
    },
    {
      "term": "OVERDOSE",
      "count": 44696
    },
    {
      "term": "PAIN",
      "count": 42151
    },
    {
      "term": "DEPENDENCE",
      "count": 36997
    },
    {
      "term": "DEATH",
      "count": 29510
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 27986
    },
    {
      "term": "FATIGUE",
      "count": 27920
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 27241
    },
    {
      "term": "OFF LABEL USE",
      "count": 26402
    },
    {
      "term": "NAUSEA",
      "count": 26086
    },
    {
      "term": "HEADACHE",
      "count": 22867
    },
    {
      "term": "DYSPNOEA",
      "count": 19626
    },
    {
      "term": "VOMITING",
      "count": 19546
    },
    {
      "term": "DIARRHOEA",
      "count": 19298
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 19038
    },
    {
      "term": "COMPLETED SUICIDE",
      "count": 19012
    },
    {
      "term": "ARTHRALGIA",
      "count": 18389
    },
    {
      "term": "PYREXIA",
      "count": 16724
    },
    {
      "term": "RASH",
      "count": 15499
    },
    {
      "term": "DIZZINESS",
      "count": 14384
    },
    {
      "term": "PNEUMONIA",
      "count": 14342
    },
    {
      "term": "ANXIETY",
      "count": 14158
    },
    {
      "term": "MALAISE",
      "count": 14106
    },
    {
      "term": "ASTHENIA",
      "count": 13479
    },
    {
      "term": "FALL",
      "count": 12606
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 12605
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 12286
    },
    {
      "term": "PRURITUS",
      "count": 12240
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 11823
    },
    {
      "term": "DEPRESSION",
      "count": 11750
    },
    {
      "term": "HYPERTENSION",
      "count": 11198
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 10723
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 10587
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 10567
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 10539
    },
    {
      "term": "JOINT SWELLING",
      "count": 10472
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 10361
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 10291
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 10067
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME",
      "count": 10047
    },
    {
      "term": "COUGH",
      "count": 9836
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 9777
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 9712
    },
    {
      "term": "INSOMNIA",
      "count": 9687
    },
    {
      "term": "SINUSITIS",
      "count": 9600
    },
    {
      "term": "HYPOTENSION",
      "count": 9537
    },
    {
      "term": "DRUG ABUSE",
      "count": 9359
    },
    {
      "term": "BACK PAIN",
      "count": 9262
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 9197
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 9193
    },
    {
      "term": "CONSTIPATION",
      "count": 8896
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 8637
    },
    {
      "term": "DECREASED APPETITE",
      "count": 8515
    },
    {
      "term": "INFECTION",
      "count": 8291
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 8206
    },
    {
      "term": "SOMNOLENCE",
      "count": 8114
    },
    {
      "term": "ALOPECIA",
      "count": 8091
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 8085
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 8051
    },
    {
      "term": "SWELLING",
      "count": 7978
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 7946
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 7915
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 7906
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 7651
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 7572
    },
    {
      "term": "CHEST PAIN",
      "count": 7450
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 7008
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 6963
    },
    {
      "term": "URTICARIA",
      "count": 6919
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 6855
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 6852
    },
    {
      "term": "INTENTIONAL OVERDOSE",
      "count": 6841
    },
    {
      "term": "RENAL FAILURE",
      "count": 6655
    },
    {
      "term": "ARTHROPATHY",
      "count": 6637
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 6595
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 6577
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 6572
    },
    {
      "term": "INJURY",
      "count": 6453
    },
    {
      "term": "ANAEMIA",
      "count": 6408
    },
    {
      "term": "COVID-19",
      "count": 6346
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 6106
    },
    {
      "term": "DRUG INTERACTION",
      "count": 6097
    },
    {
      "term": "CARDIAC DISORDER",
      "count": 6077
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME NEONATAL",
      "count": 6019
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 5967
    },
    {
      "term": "SYNOVITIS",
      "count": 5935
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 5885
    },
    {
      "term": "CONTUSION",
      "count": 5872
    },
    {
      "term": "STOMATITIS",
      "count": 5828
    },
    {
      "term": "BLISTER",
      "count": 5803
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 5795
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 5572
    },
    {
      "term": "DISCOMFORT",
      "count": 5537
    },
    {
      "term": "WOUND",
      "count": 5514
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 5444
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 5421
    },
    {
      "term": "HAND DEFORMITY",
      "count": 5376
    },
    {
      "term": "GLOSSODYNIA",
      "count": 5364
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 5322
    },
    {
      "term": "PERICARDITIS",
      "count": 5266
    }
  ]
}