{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DEATH",
      "count": 684
    },
    {
      "term": "FATIGUE",
      "count": 465
    },
    {
      "term": "ASTHENIA",
      "count": 267
    },
    {
      "term": "HOT FLUSH",
      "count": 264
    },
    {
      "term": "ANAEMIA",
      "count": 242
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 231
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 221
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 219
    },
    {
      "term": "DIARRHOEA",
      "count": 216
    },
    {
      "term": "PNEUMONIA",
      "count": 216
    },
    {
      "term": "PROSTATIC SPECIFIC ANTIGEN INCREASED",
      "count": 213
    },
    {
      "term": "THERAPY INTERRUPTED",
      "count": 206
    },
    {
      "term": "HYPERTENSION",
      "count": 205
    },
    {
      "term": "FALL",
      "count": 203
    },
    {
      "term": "NAUSEA",
      "count": 189
    },
    {
      "term": "PROSTATE CANCER",
      "count": 181
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 178
    },
    {
      "term": "DYSPNOEA",
      "count": 162
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 158
    },
    {
      "term": "VOMITING",
      "count": 150
    },
    {
      "term": "DIZZINESS",
      "count": 149
    },
    {
      "term": "DECREASED APPETITE",
      "count": 145
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 140
    },
    {
      "term": "PROSTATE CANCER METASTATIC",
      "count": 138
    },
    {
      "term": "HOSPITALISATION",
      "count": 135
    },
    {
      "term": "BACK PAIN",
      "count": 130
    },
    {
      "term": "DRUG INTERACTION",
      "count": 124
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 124
    },
    {
      "term": "SEPSIS",
      "count": 121
    },
    {
      "term": "CONSTIPATION",
      "count": 115
    },
    {
      "term": "ARTHRALGIA",
      "count": 114
    },
    {
      "term": "PYREXIA",
      "count": 109
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 108
    },
    {
      "term": "PAIN",
      "count": 102
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 100
    },
    {
      "term": "OFF LABEL USE",
      "count": 100
    },
    {
      "term": "DEHYDRATION",
      "count": 97
    },
    {
      "term": "METASTASES TO BONE",
      "count": 96
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 95
    },
    {
      "term": "THERAPY CESSATION",
      "count": 95
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 93
    },
    {
      "term": "HAEMATURIA",
      "count": 88
    },
    {
      "term": "CHEST PAIN",
      "count": 87
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 87
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 86
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 83
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 81
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 80
    },
    {
      "term": "HEADACHE",
      "count": 79
    },
    {
      "term": "SYNCOPE",
      "count": 79
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 78
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 75
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 72
    },
    {
      "term": "MALAISE",
      "count": 71
    },
    {
      "term": "NEUTROPENIA",
      "count": 70
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 69
    },
    {
      "term": "HYPOTENSION",
      "count": 69
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 69
    },
    {
      "term": "COVID-19",
      "count": 62
    },
    {
      "term": "BLOOD POTASSIUM DECREASED",
      "count": 61
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 60
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 60
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 60
    },
    {
      "term": "HOSPICE CARE",
      "count": 59
    },
    {
      "term": "INCORRECT DOSE ADMINISTERED",
      "count": 58
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 57
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 57
    },
    {
      "term": "INSOMNIA",
      "count": 56
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 56
    },
    {
      "term": "BONE PAIN",
      "count": 55
    },
    {
      "term": "RASH",
      "count": 55
    },
    {
      "term": "ACUTE MYOCARDIAL INFARCTION",
      "count": 53
    },
    {
      "term": "LIVER FUNCTION TEST ABNORMAL",
      "count": 53
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 53
    },
    {
      "term": "HYPERGLYCAEMIA",
      "count": 52
    },
    {
      "term": "URINARY RETENTION",
      "count": 52
    },
    {
      "term": "BLOOD ALKALINE PHOSPHATASE INCREASED",
      "count": 51
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 51
    },
    {
      "term": "CARDIAC FAILURE CONGESTIVE",
      "count": 51
    },
    {
      "term": "INFECTION",
      "count": 49
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 48
    },
    {
      "term": "COUGH",
      "count": 48
    },
    {
      "term": "ADVERSE EVENT",
      "count": 47
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 46
    },
    {
      "term": "ACUTE CORONARY SYNDROME",
      "count": 44
    },
    {
      "term": "FLUID RETENTION",
      "count": 43
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 43
    },
    {
      "term": "CARDIAC DISORDER",
      "count": 41
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 41
    },
    {
      "term": "SOMNOLENCE",
      "count": 41
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 40
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 40
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 40
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 40
    },
    {
      "term": "HORMONE-REFRACTORY PROSTATE CANCER",
      "count": 39
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 39
    },
    {
      "term": "RENAL FAILURE",
      "count": 39
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 38
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 38
    },
    {
      "term": "METASTASES TO LYMPH NODES",
      "count": 37
    }
  ]
}