{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DEATH",
      "count": 1562
    },
    {
      "term": "FATIGUE",
      "count": 1156
    },
    {
      "term": "HOT FLUSH",
      "count": 765
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 640
    },
    {
      "term": "PROSTATIC SPECIFIC ANTIGEN INCREASED",
      "count": 606
    },
    {
      "term": "ASTHENIA",
      "count": 604
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 547
    },
    {
      "term": "THERAPY INTERRUPTED",
      "count": 507
    },
    {
      "term": "FALL",
      "count": 468
    },
    {
      "term": "ANAEMIA",
      "count": 434
    },
    {
      "term": "DIARRHOEA",
      "count": 429
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 425
    },
    {
      "term": "NAUSEA",
      "count": 395
    },
    {
      "term": "OFF LABEL USE",
      "count": 383
    },
    {
      "term": "PROSTATE CANCER",
      "count": 370
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 370
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 362
    },
    {
      "term": "HYPERTENSION",
      "count": 362
    },
    {
      "term": "DIZZINESS",
      "count": 356
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 356
    },
    {
      "term": "PNEUMONIA",
      "count": 356
    },
    {
      "term": "DRUG INTERACTION",
      "count": 352
    },
    {
      "term": "DYSPNOEA",
      "count": 339
    },
    {
      "term": "PROSTATE CANCER METASTATIC",
      "count": 291
    },
    {
      "term": "HOSPITALISATION",
      "count": 287
    },
    {
      "term": "DECREASED APPETITE",
      "count": 284
    },
    {
      "term": "CONSTIPATION",
      "count": 277
    },
    {
      "term": "PAIN",
      "count": 277
    },
    {
      "term": "VOMITING",
      "count": 266
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 259
    },
    {
      "term": "METASTASES TO BONE",
      "count": 255
    },
    {
      "term": "ARTHRALGIA",
      "count": 253
    },
    {
      "term": "BACK PAIN",
      "count": 246
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 235
    },
    {
      "term": "SEPSIS",
      "count": 209
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 204
    },
    {
      "term": "THERAPY CESSATION",
      "count": 197
    },
    {
      "term": "HEADACHE",
      "count": 187
    },
    {
      "term": "DEHYDRATION",
      "count": 178
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 173
    },
    {
      "term": "PYREXIA",
      "count": 172
    },
    {
      "term": "COVID-19",
      "count": 170
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 168
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 162
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 157
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 156
    },
    {
      "term": "MALAISE",
      "count": 155
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 154
    },
    {
      "term": "HOSPICE CARE",
      "count": 151
    },
    {
      "term": "SYNCOPE",
      "count": 151
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 147
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 144
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 139
    },
    {
      "term": "HAEMATURIA",
      "count": 139
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 138
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 138
    },
    {
      "term": "CHEST PAIN",
      "count": 137
    },
    {
      "term": "INSOMNIA",
      "count": 135
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 134
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 131
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 129
    },
    {
      "term": "HYPOTENSION",
      "count": 127
    },
    {
      "term": "NEUTROPENIA",
      "count": 126
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 126
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 124
    },
    {
      "term": "INCORRECT DOSE ADMINISTERED",
      "count": 124
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 122
    },
    {
      "term": "BLOOD POTASSIUM DECREASED",
      "count": 119
    },
    {
      "term": "BONE PAIN",
      "count": 117
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 117
    },
    {
      "term": "HORMONE-REFRACTORY PROSTATE CANCER",
      "count": 113
    },
    {
      "term": "RASH",
      "count": 106
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 105
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 103
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 103
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 101
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 98
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 97
    },
    {
      "term": "INFECTION",
      "count": 97
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 97
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 96
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 93
    },
    {
      "term": "CARDIAC FAILURE CONGESTIVE",
      "count": 93
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 91
    },
    {
      "term": "URINARY RETENTION",
      "count": 90
    },
    {
      "term": "POLLAKIURIA",
      "count": 89
    },
    {
      "term": "RENAL FAILURE",
      "count": 89
    },
    {
      "term": "COUGH",
      "count": 87
    },
    {
      "term": "BLOOD ALKALINE PHOSPHATASE INCREASED",
      "count": 85
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 85
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 82
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 81
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 80
    },
    {
      "term": "CONTUSION",
      "count": 79
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 78
    },
    {
      "term": "MYALGIA",
      "count": 77
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 76
    },
    {
      "term": "OEDEMA",
      "count": 76
    },
    {
      "term": "DYSURIA",
      "count": 75
    },
    {
      "term": "ADVERSE EVENT",
      "count": 74
    }
  ]
}