{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-01",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "status": "Terminated",
      "city": "Thousand Oaks",
      "state": "CA",
      "country": "United States",
      "classification": "Class II",
      "openfda": {
        "application_number": [
          "NDA202714"
        ],
        "brand_name": [
          "KYPROLIS"
        ],
        "generic_name": [
          "CARFILZOMIB"
        ],
        "manufacturer_name": [
          "Onyx Pharmaceuticals, Inc."
        ],
        "product_ndc": [
          "76075-101",
          "76075-102",
          "76075-103"
        ],
        "product_type": [
          "HUMAN PRESCRIPTION DRUG"
        ],
        "route": [
          "INTRAVENOUS"
        ],
        "substance_name": [
          "CARFILZOMIB"
        ],
        "rxcui": [
          "1806934",
          "1806937",
          "1806940",
          "1806942",
          "2046642",
          "2046644"
        ],
        "spl_id": [
          "600cd22c-3a74-442e-a65d-c06d47bb892a"
        ],
        "spl_set_id": [
          "ea66eb30-e665-4693-99a1-a9d3b4bbe2d6"
        ],
        "package_ndc": [
          "76075-101-01",
          "76075-101-21",
          "76075-102-01",
          "76075-102-21",
          "76075-103-01",
          "76075-103-21"
        ],
        "is_original_packager": [
          true
        ],
        "nui": [
          "N0000175604",
          "N0000175075"
        ],
        "pharm_class_epc": [
          "Proteasome Inhibitor [EPC]"
        ],
        "pharm_class_moa": [
          "Proteasome Inhibitors [MoA]"
        ],
        "unii": [
          "72X6E3J5AR"
        ]
      },
      "product_type": "Drugs",
      "event_id": "76012",
      "recalling_firm": "Amgen, Inc.",
      "address_1": "1 Amgen Center Dr",
      "address_2": "N/A",
      "postal_code": "91320-1730",
      "voluntary_mandated": "Voluntary: Firm initiated",
      "initial_firm_notification": "Letter",
      "distribution_pattern": "United States and Puerto Rico  No foreign distribution.",
      "recall_number": "D-0226-2017",
      "product_description": "AMGEN Kyprolis (carfilzomib) for injection, 30 mg per vial,  Discard unused portion, For Intravenous Administration Only, Rx Only, Manufactured for: Onyx Pharmaceuticals, Inc., Thousand Oaks, CA 91320-1799, U.S.A., NDC 76075-102-01",
      "product_quantity": "11,434 vials",
      "reason_for_recall": "Lack of Assurance of Sterility: Potential cracks in glass vials",
      "recall_initiation_date": "20161215",
      "center_classification_date": "20161222",
      "termination_date": "20170602",
      "report_date": "20161228",
      "code_info": "Lot #1071559, 1071629; Exp. 05/18"
    }
  ]
}