{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-12",
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    {
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      "supplement_number": "S026",
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      "street_1": "5301 Stevens Creek Blvd.",
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      "supplement_reason": "Labeling Change - Indications/instructions/shelf life/tradename",
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      "decision_date": "2023-07-05",
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      "decision_code": "APPR",
      "ao_statement": "Approval for updates to Instructions for Use and manufacturing quality control technical procedure intended to mitigate nonspecific nuclear staining in formalin-fixed, paraffin-embedded (FFPE) tumor specimens stained with the Negative Control Reagent (NCR) from PD-L1 IHC 22C3 pharmDx.",
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        "medical_specialty_description": "Unknown",
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