{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-13"
  },
  "results": [
    {
      "term": "Swelling",
      "count": 2894
    },
    {
      "term": "Edema",
      "count": 2702
    },
    {
      "term": "Inflammation",
      "count": 2622
    },
    {
      "term": "Skin Irritation",
      "count": 2543
    },
    {
      "term": "Erythema",
      "count": 2232
    },
    {
      "term": "Pain",
      "count": 2137
    },
    {
      "term": "Unspecified Infection",
      "count": 2003
    },
    {
      "term": "Hypersensitivity/Allergic reaction",
      "count": 1918
    },
    {
      "term": "Nodule",
      "count": 1850
    },
    {
      "term": "Obstruction/Occlusion",
      "count": 1548
    },
    {
      "term": "Abscess",
      "count": 1374
    },
    {
      "term": "Treatment with medication(s)",
      "count": 1297
    },
    {
      "term": "Skin Discoloration",
      "count": 1061
    },
    {
      "term": "Granuloma",
      "count": 1006
    },
    {
      "term": "Necrosis",
      "count": 934
    },
    {
      "term": "Subcutaneous Nodule",
      "count": 805
    },
    {
      "term": "No Consequences Or Impact To Patient",
      "count": 744
    },
    {
      "term": "No Known Impact Or Consequence To Patient",
      "count": 738
    },
    {
      "term": "Swelling/ Edema",
      "count": 605
    },
    {
      "term": "Vascular System (Circulation), Impaired",
      "count": 566
    },
    {
      "term": "Bruise/Contusion",
      "count": 549
    },
    {
      "term": "Itching Sensation",
      "count": 473
    },
    {
      "term": "No Code Available",
      "count": 470
    },
    {
      "term": "Other (for use when an appropriate patient code cannot be identified)",
      "count": 468
    },
    {
      "term": "Appropriate Clinical Signs, Symptoms and Conditions Term/Code Not Available",
      "count": 449
    },
    {
      "term": "Ischemia",
      "count": 403
    },
    {
      "term": "Cellulitis",
      "count": 371
    },
    {
      "term": "Therapy/non-surgical treatment, additional",
      "count": 367
    },
    {
      "term": "Skin Inflammation",
      "count": 338
    },
    {
      "term": "Bacterial Infection",
      "count": 313
    },
    {
      "term": "Rash",
      "count": 312
    },
    {
      "term": "No Clinical Signs, Symptoms or Conditions",
      "count": 306
    },
    {
      "term": "Reaction",
      "count": 306
    },
    {
      "term": "Ecchymosis",
      "count": 290
    },
    {
      "term": "Scarring",
      "count": 264
    },
    {
      "term": "Foreign Body Embolism",
      "count": 260
    },
    {
      "term": "Purulent Discharge",
      "count": 239
    },
    {
      "term": "Deformity/ Disfigurement",
      "count": 238
    },
    {
      "term": "Viral Infection",
      "count": 230
    },
    {
      "term": "Numbness",
      "count": 213
    },
    {
      "term": "Headache",
      "count": 210
    },
    {
      "term": "Scar Tissue",
      "count": 206
    },
    {
      "term": "Occlusion",
      "count": 191
    },
    {
      "term": "Foreign Body Reaction",
      "count": 188
    },
    {
      "term": "Skin Infection",
      "count": 176
    },
    {
      "term": "Skin Inflammation/ Irritation",
      "count": 174
    },
    {
      "term": "Loss of Vision",
      "count": 171
    },
    {
      "term": "Fever",
      "count": 162
    },
    {
      "term": "Discomfort",
      "count": 157
    },
    {
      "term": "Hematoma",
      "count": 152
    },
    {
      "term": "Fluid Discharge",
      "count": 149
    },
    {
      "term": "Dyspnea",
      "count": 139
    },
    {
      "term": "Local Reaction",
      "count": 139
    },
    {
      "term": "Herpes",
      "count": 135
    },
    {
      "term": "Allergic reaction",
      "count": 134
    },
    {
      "term": "Burning Sensation",
      "count": 131
    },
    {
      "term": "Cyst(s)",
      "count": 130
    },
    {
      "term": "Visual Impairment",
      "count": 127
    },
    {
      "term": "Blurred Vision",
      "count": 126
    },
    {
      "term": "Patient Problem/Medical Problem",
      "count": 120
    },
    {
      "term": "Anxiety",
      "count": 110
    },
    {
      "term": "Administration Site Reaction",
      "count": 108
    },
    {
      "term": "Respiratory Tract Infection",
      "count": 108
    },
    {
      "term": "Autoimmune Disorder",
      "count": 106
    },
    {
      "term": "Nausea",
      "count": 105
    },
    {
      "term": "Tissue Damage",
      "count": 99
    },
    {
      "term": "Surgical procedure",
      "count": 98
    },
    {
      "term": "Urticaria",
      "count": 98
    },
    {
      "term": "Reaction, Injection Site",
      "count": 97
    },
    {
      "term": "Pallor",
      "count": 96
    },
    {
      "term": "Malaise",
      "count": 94
    },
    {
      "term": "Complaint, Ill-Defined",
      "count": 93
    },
    {
      "term": "Discharge",
      "count": 93
    },
    {
      "term": "Tingling",
      "count": 92
    },
    {
      "term": "Urinary Tract Infection",
      "count": 91
    },
    {
      "term": "Anaphylactic Shock",
      "count": 90
    },
    {
      "term": "Swollen Lymph Nodes/Glands",
      "count": 87
    },
    {
      "term": "Peeling",
      "count": 86
    },
    {
      "term": "Visual Disturbances",
      "count": 84
    },
    {
      "term": "Hemorrhage/Blood Loss/Bleeding",
      "count": 81
    },
    {
      "term": "Implant Pain",
      "count": 81
    },
    {
      "term": "Angioedema",
      "count": 77
    },
    {
      "term": "Dizziness",
      "count": 75
    },
    {
      "term": "Swollen Lymph Nodes",
      "count": 66
    },
    {
      "term": "Ulcer",
      "count": 64
    },
    {
      "term": "Blister(s)",
      "count": 61
    },
    {
      "term": "Skin Erosion",
      "count": 60
    },
    {
      "term": "Fibrosis",
      "count": 57
    },
    {
      "term": "Embolism/Embolus",
      "count": 55
    },
    {
      "term": "Fatigue",
      "count": 55
    },
    {
      "term": "Irritation",
      "count": 54
    },
    {
      "term": "Vomiting",
      "count": 54
    },
    {
      "term": "Depression",
      "count": 53
    },
    {
      "term": "Paralysis",
      "count": 53
    },
    {
      "term": "Autoimmune Reaction",
      "count": 52
    },
    {
      "term": "Cancer",
      "count": 51
    },
    {
      "term": "Dysphagia/ Odynophagia",
      "count": 48
    },
    {
      "term": "Facial Nerve Paralysis",
      "count": 48
    },
    {
      "term": "Tachycardia",
      "count": 47
    },
    {
      "term": "Stroke/CVA",
      "count": 46
    }
  ]
}