{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Ketosis",
      "count": 1543
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 1054
    },
    {
      "term": "Weight loss",
      "count": 1007
    },
    {
      "term": "Diarrhoea",
      "count": 697
    },
    {
      "term": "Vomiting",
      "count": 617
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 557
    },
    {
      "term": "Ketonuria",
      "count": 520
    },
    {
      "term": "Anorexia",
      "count": 402
    },
    {
      "term": "Death by euthanasia",
      "count": 271
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 245
    },
    {
      "term": "Hypokalaemia",
      "count": 212
    },
    {
      "term": "Dehydration",
      "count": 197
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 191
    },
    {
      "term": "Diabetic ketoacidosis",
      "count": 168
    },
    {
      "term": "Hypochloraemia",
      "count": 165
    },
    {
      "term": "Elevated cholesterol (total)",
      "count": 151
    },
    {
      "term": "Urinary tract infection",
      "count": 146
    },
    {
      "term": "High pancreatic-specific lipase",
      "count": 137
    },
    {
      "term": "Not eating",
      "count": 136
    },
    {
      "term": "Hypoglycaemia",
      "count": 127
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 125
    },
    {
      "term": "Polydipsia",
      "count": 125
    },
    {
      "term": "Elevated total bilirubin",
      "count": 121
    },
    {
      "term": "Proteinuria",
      "count": 121
    },
    {
      "term": "Polyuria",
      "count": 115
    },
    {
      "term": "Elevated creatinine",
      "count": 110
    },
    {
      "term": "Decreased appetite",
      "count": 109
    },
    {
      "term": "Partial anorexia",
      "count": 106
    },
    {
      "term": "Elevated globulins",
      "count": 96
    },
    {
      "term": "Neutrophilia",
      "count": 90
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 88
    },
    {
      "term": "Inappropriate urination",
      "count": 85
    },
    {
      "term": "Hiding",
      "count": 84
    },
    {
      "term": "Inappetence",
      "count": 83
    },
    {
      "term": "Hyperproteinaemia",
      "count": 77
    },
    {
      "term": "Hypercalcaemia",
      "count": 76
    },
    {
      "term": "Loose stool",
      "count": 76
    },
    {
      "term": "Death",
      "count": 74
    },
    {
      "term": "Hyperphosphataemia",
      "count": 73
    },
    {
      "term": "Hyponatremia",
      "count": 71
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 68
    },
    {
      "term": "Foaming at the mouth",
      "count": 64
    },
    {
      "term": "Hyperalbuminaemia",
      "count": 62
    },
    {
      "term": "Drooling",
      "count": 61
    },
    {
      "term": "Hypersalivation",
      "count": 61
    },
    {
      "term": "Leucocytosis NOS",
      "count": 61
    },
    {
      "term": "Monocytosis",
      "count": 60
    },
    {
      "term": "Pancreatitis NOS",
      "count": 59
    },
    {
      "term": "Haematuria",
      "count": 58
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 48
    },
    {
      "term": "Soft stool",
      "count": 47
    },
    {
      "term": "Hypophosphataemia",
      "count": 46
    },
    {
      "term": "Polyphagia",
      "count": 46
    },
    {
      "term": "Elevated lipase",
      "count": 40
    },
    {
      "term": "Decreased packed cell volume (PCV)",
      "count": 38
    },
    {
      "term": "Acid-base disorder",
      "count": 37
    },
    {
      "term": "Elevated triglyceride",
      "count": 37
    },
    {
      "term": "Blood in urine",
      "count": 34
    },
    {
      "term": "Gagging",
      "count": 33
    },
    {
      "term": "Lymphopenia",
      "count": 33
    },
    {
      "term": "Hypernatremia",
      "count": 32
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 31
    },
    {
      "term": "Glucosuria",
      "count": 31
    },
    {
      "term": "Hyperglycaemia",
      "count": 31
    },
    {
      "term": "Constipation",
      "count": 30
    },
    {
      "term": "Fever",
      "count": 30
    },
    {
      "term": "Weight gain",
      "count": 30
    },
    {
      "term": "Heart murmur",
      "count": 29
    },
    {
      "term": "Ataxia",
      "count": 28
    },
    {
      "term": "Not drinking",
      "count": 28
    },
    {
      "term": "Hypothermia",
      "count": 26
    },
    {
      "term": "Lateral recumbency",
      "count": 26
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 24
    },
    {
      "term": "Elevated fructosamine",
      "count": 24
    },
    {
      "term": "Vocalisation",
      "count": 24
    },
    {
      "term": "Adipsia",
      "count": 23
    },
    {
      "term": "Anaemia NOS",
      "count": 23
    },
    {
      "term": "Elevated amylase",
      "count": 22
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 22
    },
    {
      "term": "Icterus",
      "count": 22
    },
    {
      "term": "Weakness",
      "count": 22
    },
    {
      "term": "General illness",
      "count": 21
    },
    {
      "term": "Increased urine concentration",
      "count": 20
    },
    {
      "term": "Azotaemia",
      "count": 19
    },
    {
      "term": "Decreased haematocrit",
      "count": 19
    },
    {
      "term": "Decreased urine concentration",
      "count": 19
    },
    {
      "term": "Low creatinine",
      "count": 19
    },
    {
      "term": "Unkempt hair coat",
      "count": 19
    },
    {
      "term": "Urine abnormalities NOS",
      "count": 19
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 18
    },
    {
      "term": "Muscle wasting",
      "count": 18
    },
    {
      "term": "Hypocalcaemia",
      "count": 17
    },
    {
      "term": "Increased appetite",
      "count": 17
    },
    {
      "term": "Overdose",
      "count": 17
    },
    {
      "term": "Eosinophilia",
      "count": 16
    },
    {
      "term": "Hyperkalaemia",
      "count": 16
    },
    {
      "term": "Product defect, product difficult to use/handle (see also 'Drug device difficult to use/handle')",
      "count": 16
    },
    {
      "term": "Seizure NOS",
      "count": 16
    },
    {
      "term": "Bilirubinuria",
      "count": 15
    },
    {
      "term": "Decreased red blood cell count",
      "count": 15
    }
  ]
}