{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 1992
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 1973
    },
    {
      "term": "Hyperkalaemia",
      "count": 1741
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 1687
    },
    {
      "term": "Weight loss",
      "count": 1478
    },
    {
      "term": "Underdose",
      "count": 1430
    },
    {
      "term": "Diarrhoea",
      "count": 1422
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 1372
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 1121
    },
    {
      "term": "Decreased appetite",
      "count": 1095
    },
    {
      "term": "Anorexia",
      "count": 1085
    },
    {
      "term": "INEFFECTIVE, CUSHINGS",
      "count": 977
    },
    {
      "term": "Death by euthanasia",
      "count": 904
    },
    {
      "term": "Polydipsia",
      "count": 850
    },
    {
      "term": "Abnormal adrenocorticotropic hormone (ACTH) stimulation test",
      "count": 843
    },
    {
      "term": "Low sodium-potassium ratio (Na:K ratio)",
      "count": 837
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 816
    },
    {
      "term": "Polyuria",
      "count": 762
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 700
    },
    {
      "term": "Hypoadrenocorticism",
      "count": 689
    },
    {
      "term": "Decreased urine concentration",
      "count": 653
    },
    {
      "term": "Urinary tract infection",
      "count": 585
    },
    {
      "term": "Panting",
      "count": 560
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 543
    },
    {
      "term": "Proteinuria",
      "count": 541
    },
    {
      "term": "Elevated creatinine",
      "count": 531
    },
    {
      "term": "Hyperglycaemia",
      "count": 520
    },
    {
      "term": "Weakness",
      "count": 485
    },
    {
      "term": "Hyponatremia",
      "count": 461
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 456
    },
    {
      "term": "Electrolyte disorder",
      "count": 452
    },
    {
      "term": "Thrombocytosis",
      "count": 442
    },
    {
      "term": "Inappetence",
      "count": 433
    },
    {
      "term": "Not eating",
      "count": 431
    },
    {
      "term": "Shaking",
      "count": 429
    },
    {
      "term": "Hypocortisolaemia",
      "count": 423
    },
    {
      "term": "Inappropriate urination",
      "count": 400
    },
    {
      "term": "Weight gain",
      "count": 381
    },
    {
      "term": "Death",
      "count": 374
    },
    {
      "term": "Hyperphosphataemia",
      "count": 369
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 369
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 348
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 341
    },
    {
      "term": "Seizure NOS",
      "count": 330
    },
    {
      "term": "Hypochloraemia",
      "count": 318
    },
    {
      "term": "Elevated cholesterol (total)",
      "count": 305
    },
    {
      "term": "Malaise",
      "count": 284
    },
    {
      "term": "Elevated liver enzymes",
      "count": 267
    },
    {
      "term": "Diabetes mellitus",
      "count": 241
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 235
    },
    {
      "term": "Loose stool",
      "count": 229
    },
    {
      "term": "Limb weakness",
      "count": 226
    },
    {
      "term": "Polyphagia",
      "count": 225
    },
    {
      "term": "Hypercalcaemia",
      "count": 223
    },
    {
      "term": "Distension of abdomen",
      "count": 216
    },
    {
      "term": "Pancreatitis",
      "count": 215
    },
    {
      "term": "Depression",
      "count": 214
    },
    {
      "term": "Bloody diarrhoea",
      "count": 209
    },
    {
      "term": "Adrenal gland disorder NOS",
      "count": 208
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 208
    },
    {
      "term": "Elevated lipase",
      "count": 205
    },
    {
      "term": "Arthritis",
      "count": 202
    },
    {
      "term": "INEFFECTIVE, LOSS OF EFFECT",
      "count": 200
    },
    {
      "term": "Anxiety",
      "count": 199
    },
    {
      "term": "Dehydration",
      "count": 191
    },
    {
      "term": "Leucocytosis NOS",
      "count": 191
    },
    {
      "term": "Ataxia",
      "count": 186
    },
    {
      "term": "Uncoded sign",
      "count": 181
    },
    {
      "term": "Trembling",
      "count": 171
    },
    {
      "term": "Restlessness",
      "count": 170
    },
    {
      "term": "Anaemia NOS",
      "count": 163
    },
    {
      "term": "Cough",
      "count": 161
    },
    {
      "term": "Heart murmur",
      "count": 158
    },
    {
      "term": "Neutrophilia",
      "count": 155
    },
    {
      "term": "Glucosuria",
      "count": 146
    },
    {
      "term": "Hypoglycaemia",
      "count": 144
    },
    {
      "term": "Haemolysis",
      "count": 143
    },
    {
      "term": "Hypernatremia",
      "count": 142
    },
    {
      "term": "Addison's disease",
      "count": 139
    },
    {
      "term": "Cutaneous calcinosis",
      "count": 136
    },
    {
      "term": "Elevated amylase",
      "count": 135
    },
    {
      "term": "Gall bladder & bile duct disorder NOS",
      "count": 133
    },
    {
      "term": "Haematuria",
      "count": 132
    },
    {
      "term": "Lipaemia",
      "count": 131
    },
    {
      "term": "Muscle wasting",
      "count": 130
    },
    {
      "term": "Elevated protein:creatinine ratio",
      "count": 129
    },
    {
      "term": "Hypertension",
      "count": 129
    },
    {
      "term": "Elevated total bilirubin",
      "count": 123
    },
    {
      "term": "Elevated triglyceride",
      "count": 121
    },
    {
      "term": "Tremor",
      "count": 120
    },
    {
      "term": "Urinary incontinence",
      "count": 118
    },
    {
      "term": "Diabetes",
      "count": 117
    },
    {
      "term": "High sodium-potassium ratio (Na:K ratio)",
      "count": 115
    },
    {
      "term": "Lymphopenia",
      "count": 115
    },
    {
      "term": "Low thyroxine (T4)",
      "count": 112
    },
    {
      "term": "Urine abnormalities NOS",
      "count": 111
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 110
    },
    {
      "term": "Hair loss NOS",
      "count": 110
    },
    {
      "term": "Decreased activity",
      "count": 109
    },
    {
      "term": "Decreased packed cell volume (PCV)",
      "count": 109
    }
  ]
}