{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Diarrhoea",
      "count": 224
    },
    {
      "term": "Vomiting",
      "count": 194
    },
    {
      "term": "Anorexia",
      "count": 164
    },
    {
      "term": "Anaemia NOS",
      "count": 107
    },
    {
      "term": "Neutropenia",
      "count": 100
    },
    {
      "term": "Lameness",
      "count": 97
    },
    {
      "term": "Death by euthanasia",
      "count": 96
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 87
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 86
    },
    {
      "term": "Weight loss",
      "count": 84
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 82
    },
    {
      "term": "Leucopenia NOS",
      "count": 82
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 70
    },
    {
      "term": "Death",
      "count": 61
    },
    {
      "term": "Decreased appetite",
      "count": 60
    },
    {
      "term": "Depression",
      "count": 59
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 48
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 47
    },
    {
      "term": "Loose stool",
      "count": 46
    },
    {
      "term": "Bloody diarrhoea",
      "count": 44
    },
    {
      "term": "Thrombocytopenia",
      "count": 44
    },
    {
      "term": "Underdose",
      "count": 42
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 40
    },
    {
      "term": "Fever",
      "count": 39
    },
    {
      "term": "Proteinuria",
      "count": 39
    },
    {
      "term": "Elevated liver enzymes",
      "count": 35
    },
    {
      "term": "Weakness",
      "count": 35
    },
    {
      "term": "INEFFECTIVE, NEOPLASIA",
      "count": 33
    },
    {
      "term": "Pancreatitis",
      "count": 33
    },
    {
      "term": "Ataxia",
      "count": 30
    },
    {
      "term": "Hyperextension",
      "count": 28
    },
    {
      "term": "Leucocytosis NOS",
      "count": 27
    },
    {
      "term": "Nausea",
      "count": 27
    },
    {
      "term": "Not eating",
      "count": 27
    },
    {
      "term": "Hypopigmentation",
      "count": 25
    },
    {
      "term": "Inappetence",
      "count": 24
    },
    {
      "term": "Elevated creatinine",
      "count": 23
    },
    {
      "term": "Pain NOS",
      "count": 21
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 20
    },
    {
      "term": "Blood in faeces",
      "count": 20
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 20
    },
    {
      "term": "Pale mucous membrane",
      "count": 20
    },
    {
      "term": "Skin lesion NOS",
      "count": 20
    },
    {
      "term": "Elevated total bilirubin",
      "count": 19
    },
    {
      "term": "Hind limb paresis",
      "count": 19
    },
    {
      "term": "Lymphopenia",
      "count": 19
    },
    {
      "term": "Intentional misuse",
      "count": 18
    },
    {
      "term": "Pruritus",
      "count": 18
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 17
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 17
    },
    {
      "term": "Musculoskeletal disorder NOS",
      "count": 17
    },
    {
      "term": "Polyuria",
      "count": 17
    },
    {
      "term": "Haematochezia",
      "count": 16
    },
    {
      "term": "Hair coat discolouration",
      "count": 16
    },
    {
      "term": "Ineffective, Neoplasia",
      "count": 16
    },
    {
      "term": "Melaena",
      "count": 16
    },
    {
      "term": "Panting",
      "count": 16
    },
    {
      "term": "Epistaxis",
      "count": 15
    },
    {
      "term": "Hypertension",
      "count": 15
    },
    {
      "term": "Urinary tract infection",
      "count": 15
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 14
    },
    {
      "term": "Hypoproteinaemia",
      "count": 14
    },
    {
      "term": "Polydipsia",
      "count": 14
    },
    {
      "term": "Seizure NOS",
      "count": 14
    },
    {
      "term": "Dehydration",
      "count": 13
    },
    {
      "term": "Dyspnoea",
      "count": 13
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 13
    },
    {
      "term": "Musculoskeletal pain",
      "count": 13
    },
    {
      "term": "Alopecia NOS",
      "count": 12
    },
    {
      "term": "Azotaemia",
      "count": 12
    },
    {
      "term": "Blood in vomit",
      "count": 12
    },
    {
      "term": "Emesis",
      "count": 12
    },
    {
      "term": "Emesis (multiple)",
      "count": 12
    },
    {
      "term": "Lymphadenopathy",
      "count": 12
    },
    {
      "term": "Recumbency",
      "count": 12
    },
    {
      "term": "Reluctant to move",
      "count": 12
    },
    {
      "term": "Trembling",
      "count": 12
    },
    {
      "term": "Hyperphosphataemia",
      "count": 11
    },
    {
      "term": "Neutrophilia",
      "count": 11
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 10
    },
    {
      "term": "Elevated lipase",
      "count": 10
    },
    {
      "term": "INEFFECTIVE, LOSS OF EFFECT",
      "count": 10
    },
    {
      "term": "Localised pain NOS (see other 'SOCs' for specific pain)",
      "count": 10
    },
    {
      "term": "Urinary incontinence",
      "count": 10
    },
    {
      "term": "Appetite loss",
      "count": 9
    },
    {
      "term": "Collapse (see also 'Cardio-vascular' and 'Systemic disorders')",
      "count": 9
    },
    {
      "term": "Convulsion",
      "count": 9
    },
    {
      "term": "Elevated renal parameters",
      "count": 9
    },
    {
      "term": "Inappropriate schedule of drug administration",
      "count": 9
    },
    {
      "term": "Limb weakness",
      "count": 9
    },
    {
      "term": "Limping",
      "count": 9
    },
    {
      "term": "PR-LIVER, LESION(S)",
      "count": 9
    },
    {
      "term": "Pigmentation disorder",
      "count": 9
    },
    {
      "term": "Tachycardia",
      "count": 9
    },
    {
      "term": "Abdominal pain",
      "count": 8
    },
    {
      "term": "Adipsia",
      "count": 8
    },
    {
      "term": "Decreased packed cell volume (PCV)",
      "count": 8
    },
    {
      "term": "Dermatitis",
      "count": 8
    },
    {
      "term": "Malaise",
      "count": 8
    },
    {
      "term": "Medication error NOS",
      "count": 8
    }
  ]
}