{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Lack of efficacy - NOS",
      "count": 106
    },
    {
      "term": "Vomiting",
      "count": 99
    },
    {
      "term": "Weight loss",
      "count": 45
    },
    {
      "term": "Decreased appetite",
      "count": 32
    },
    {
      "term": "Elevated creatinine",
      "count": 30
    },
    {
      "term": "Death by euthanasia",
      "count": 28
    },
    {
      "term": "Dehydration",
      "count": 27
    },
    {
      "term": "Diarrhoea",
      "count": 25
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 24
    },
    {
      "term": "Inappetence",
      "count": 19
    },
    {
      "term": "Anaemia NOS",
      "count": 18
    },
    {
      "term": "Heart murmur",
      "count": 17
    },
    {
      "term": "Urinary tract infection",
      "count": 17
    },
    {
      "term": "Constipation",
      "count": 16
    },
    {
      "term": "Dental disease",
      "count": 14
    },
    {
      "term": "Haematuria",
      "count": 14
    },
    {
      "term": "Hypotension",
      "count": 14
    },
    {
      "term": "Arthritis",
      "count": 13
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 13
    },
    {
      "term": "Sneezing",
      "count": 13
    },
    {
      "term": "Hyperphosphataemia",
      "count": 12
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 12
    },
    {
      "term": "Not eating",
      "count": 12
    },
    {
      "term": "Nasal discharge",
      "count": 11
    },
    {
      "term": "Vocalisation",
      "count": 11
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 10
    },
    {
      "term": "Anorexia",
      "count": 9
    },
    {
      "term": "Inappropriate urination",
      "count": 9
    },
    {
      "term": "Respiratory tract infection NOS",
      "count": 9
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 8
    },
    {
      "term": "Gingivitis",
      "count": 8
    },
    {
      "term": "Hyperglycaemia",
      "count": 8
    },
    {
      "term": "Ocular discharge",
      "count": 7
    },
    {
      "term": "Polydipsia",
      "count": 7
    },
    {
      "term": "Renal disorder NOS",
      "count": 7
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 6
    },
    {
      "term": "Cough",
      "count": 6
    },
    {
      "term": "Cystitis",
      "count": 6
    },
    {
      "term": "Gagging",
      "count": 6
    },
    {
      "term": "Hiding",
      "count": 6
    },
    {
      "term": "Hypercalcaemia",
      "count": 6
    },
    {
      "term": "Hypokalaemia",
      "count": 6
    },
    {
      "term": "Muscle atrophy (see also 'Muscle wasting')",
      "count": 6
    },
    {
      "term": "Muscle wasting",
      "count": 6
    },
    {
      "term": "Non-regenerative anaemia",
      "count": 6
    },
    {
      "term": "Pancreatitis NOS",
      "count": 6
    },
    {
      "term": "Polyuria",
      "count": 6
    },
    {
      "term": "Proteinuria",
      "count": 6
    },
    {
      "term": "Thyroid gland disorder NOS",
      "count": 6
    },
    {
      "term": "Abdominal pain",
      "count": 5
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 5
    },
    {
      "term": "Ataxia",
      "count": 5
    },
    {
      "term": "Conjunctivitis",
      "count": 5
    },
    {
      "term": "Death",
      "count": 5
    },
    {
      "term": "Dental calculus",
      "count": 5
    },
    {
      "term": "Dermal mass",
      "count": 5
    },
    {
      "term": "Hypernatremia",
      "count": 5
    },
    {
      "term": "Hypoglycaemia",
      "count": 5
    },
    {
      "term": "Inappropriate defecation",
      "count": 5
    },
    {
      "term": "Intestinal disorder NOS",
      "count": 5
    },
    {
      "term": "Less social",
      "count": 5
    },
    {
      "term": "Loose stool",
      "count": 5
    },
    {
      "term": "Neutrophilia",
      "count": 5
    },
    {
      "term": "Skin scab",
      "count": 5
    },
    {
      "term": "Soft stool",
      "count": 5
    },
    {
      "term": "Azotaemia",
      "count": 4
    },
    {
      "term": "Balance problem",
      "count": 4
    },
    {
      "term": "Dermal cyst(s)",
      "count": 4
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 4
    },
    {
      "term": "Drooling",
      "count": 4
    },
    {
      "term": "Ear discharge",
      "count": 4
    },
    {
      "term": "Elevated amylase",
      "count": 4
    },
    {
      "term": "Elevated globulins",
      "count": 4
    },
    {
      "term": "Hypertension",
      "count": 4
    },
    {
      "term": "INEFFECTIVE, LOSS OF EFFECT",
      "count": 4
    },
    {
      "term": "Mydriasis",
      "count": 4
    },
    {
      "term": "Not drinking",
      "count": 4
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 4
    },
    {
      "term": "Otitis externa",
      "count": 4
    },
    {
      "term": "Stranguria",
      "count": 4
    },
    {
      "term": "Unable to jump",
      "count": 4
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 3
    },
    {
      "term": "Anxiety",
      "count": 3
    },
    {
      "term": "Arrhythmia",
      "count": 3
    },
    {
      "term": "Blood in urine",
      "count": 3
    },
    {
      "term": "Cataract",
      "count": 3
    },
    {
      "term": "Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders')",
      "count": 3
    },
    {
      "term": "Crystalluria",
      "count": 3
    },
    {
      "term": "Decreased body temperature",
      "count": 3
    },
    {
      "term": "Decreased haematocrit",
      "count": 3
    },
    {
      "term": "Decreased red blood cell count",
      "count": 3
    },
    {
      "term": "Decreased urine concentration",
      "count": 3
    },
    {
      "term": "Depression",
      "count": 3
    },
    {
      "term": "Dullness",
      "count": 3
    },
    {
      "term": "Ear infection NOS",
      "count": 3
    },
    {
      "term": "Ear pruritus",
      "count": 3
    },
    {
      "term": "Elevated creatine-kinase (CK)",
      "count": 3
    },
    {
      "term": "Elevated renal parameters",
      "count": 3
    },
    {
      "term": "Elevated temperature",
      "count": 3
    },
    {
      "term": "Elevated thyroxine (T4)",
      "count": 3
    }
  ]
}