{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Death",
      "count": 223
    },
    {
      "term": "Cardiac arrest",
      "count": 149
    },
    {
      "term": "Apnoea",
      "count": 120
    },
    {
      "term": "Bradycardia",
      "count": 112
    },
    {
      "term": "Vomiting",
      "count": 99
    },
    {
      "term": "INEFFECTIVE, ANESTHESIA",
      "count": 61
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 59
    },
    {
      "term": "Anorexia",
      "count": 54
    },
    {
      "term": "Tachycardia",
      "count": 44
    },
    {
      "term": "Diarrhoea",
      "count": 43
    },
    {
      "term": "Pale mucous membrane",
      "count": 41
    },
    {
      "term": "Cyanosis",
      "count": 32
    },
    {
      "term": "Death by euthanasia",
      "count": 31
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 29
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 29
    },
    {
      "term": "Fever",
      "count": 28
    },
    {
      "term": "Hypothermia",
      "count": 28
    },
    {
      "term": "Bloody diarrhoea",
      "count": 27
    },
    {
      "term": "Recovery prolonged",
      "count": 27
    },
    {
      "term": "Tachypnoea",
      "count": 27
    },
    {
      "term": "Anaemia NOS",
      "count": 26
    },
    {
      "term": "Vocalisation",
      "count": 25
    },
    {
      "term": "Hypotension",
      "count": 24
    },
    {
      "term": "Not eating",
      "count": 24
    },
    {
      "term": "Decreased appetite",
      "count": 23
    },
    {
      "term": "Panting",
      "count": 23
    },
    {
      "term": "Elevated creatinine",
      "count": 22
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 20
    },
    {
      "term": "Anaphylaxis",
      "count": 19
    },
    {
      "term": "Dyspnoea",
      "count": 19
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 19
    },
    {
      "term": "Hypersalivation",
      "count": 19
    },
    {
      "term": "Seizure NOS",
      "count": 19
    },
    {
      "term": "Weight loss",
      "count": 19
    },
    {
      "term": "Arrhythmia",
      "count": 18
    },
    {
      "term": "Convulsion",
      "count": 18
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 18
    },
    {
      "term": "Leucocytosis NOS",
      "count": 18
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 17
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 17
    },
    {
      "term": "Depression",
      "count": 16
    },
    {
      "term": "Hyperexcitation",
      "count": 16
    },
    {
      "term": "Blood and lymphatic system disorder NOS",
      "count": 15
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 15
    },
    {
      "term": "Pain NOS",
      "count": 15
    },
    {
      "term": "Elevated total bilirubin",
      "count": 14
    },
    {
      "term": "Neutrophilia",
      "count": 14
    },
    {
      "term": "Dehydration",
      "count": 13
    },
    {
      "term": "Facial swelling (see also 'Skin')",
      "count": 13
    },
    {
      "term": "Hyperphosphataemia",
      "count": 13
    },
    {
      "term": "Shock",
      "count": 13
    },
    {
      "term": "Abnormal breathing",
      "count": 12
    },
    {
      "term": "Ataxia",
      "count": 12
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 12
    },
    {
      "term": "Bradypnoea",
      "count": 12
    },
    {
      "term": "Emesis",
      "count": 12
    },
    {
      "term": "Immune mediated haemolytic anaemia",
      "count": 12
    },
    {
      "term": "Injection site swelling",
      "count": 12
    },
    {
      "term": "Restlessness",
      "count": 12
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 11
    },
    {
      "term": "Hypoproteinaemia",
      "count": 11
    },
    {
      "term": "Inappetence",
      "count": 11
    },
    {
      "term": "Haemorrhagic gastroenteritis",
      "count": 10
    },
    {
      "term": "Leucopenia NOS",
      "count": 10
    },
    {
      "term": "Thrombocytopenia",
      "count": 10
    },
    {
      "term": "Elevated temperature",
      "count": 9
    },
    {
      "term": "Hives (see also 'Skin')",
      "count": 9
    },
    {
      "term": "Polypnoea",
      "count": 9
    },
    {
      "term": "Sedation prolonged",
      "count": 9
    },
    {
      "term": "Abdominal pain",
      "count": 8
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 8
    },
    {
      "term": "Heart block NOS",
      "count": 8
    },
    {
      "term": "Hyperactivity",
      "count": 8
    },
    {
      "term": "Inappropriate urination",
      "count": 8
    },
    {
      "term": "Monocytosis",
      "count": 8
    },
    {
      "term": "Mydriasis",
      "count": 8
    },
    {
      "term": "Pacing",
      "count": 8
    },
    {
      "term": "Regurgitation",
      "count": 8
    },
    {
      "term": "Respiratory distress",
      "count": 8
    },
    {
      "term": "Respiratory tract disorder NOS",
      "count": 8
    },
    {
      "term": "Tarry or black stool (see also haemorrhagic diarrhoea)",
      "count": 8
    },
    {
      "term": "Twitching",
      "count": 8
    },
    {
      "term": "Anxiety",
      "count": 7
    },
    {
      "term": "Bruising",
      "count": 7
    },
    {
      "term": "Cough",
      "count": 7
    },
    {
      "term": "Elevated liver enzymes",
      "count": 7
    },
    {
      "term": "Icterus",
      "count": 7
    },
    {
      "term": "Intentional misuse",
      "count": 7
    },
    {
      "term": "Laboured breathing",
      "count": 7
    },
    {
      "term": "Lateral recumbency",
      "count": 7
    },
    {
      "term": "Loose stool",
      "count": 7
    },
    {
      "term": "Lung oedema",
      "count": 7
    },
    {
      "term": "Lymphadenopathy",
      "count": 7
    },
    {
      "term": "PR-HEART, LESION(S)",
      "count": 7
    },
    {
      "term": "Paddling",
      "count": 7
    },
    {
      "term": "Reddening of the skin",
      "count": 7
    },
    {
      "term": "Skin lesion NOS",
      "count": 7
    },
    {
      "term": "Trembling",
      "count": 7
    },
    {
      "term": "Uncomfortable",
      "count": 7
    },
    {
      "term": "Weakness",
      "count": 7
    }
  ]
}