{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 449
    },
    {
      "term": "INEFFECTIVE, COGNITIVE DYSFUNC",
      "count": 439
    },
    {
      "term": "INEFFECTIVE, LOSS OF EFFECT",
      "count": 338
    },
    {
      "term": "Diarrhoea",
      "count": 337
    },
    {
      "term": "Anorexia",
      "count": 324
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 311
    },
    {
      "term": "Depression",
      "count": 301
    },
    {
      "term": "Restlessness",
      "count": 262
    },
    {
      "term": "INEFFECTIVE, CUSHINGS",
      "count": 252
    },
    {
      "term": "Death by euthanasia",
      "count": 243
    },
    {
      "term": "Convulsion",
      "count": 231
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 226
    },
    {
      "term": "Polypnoea",
      "count": 214
    },
    {
      "term": "Polydipsia",
      "count": 190
    },
    {
      "term": "Hyperactivity",
      "count": 182
    },
    {
      "term": "Confusion",
      "count": 174
    },
    {
      "term": "Ataxia",
      "count": 173
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 161
    },
    {
      "term": "Polyuria",
      "count": 158
    },
    {
      "term": "Weight loss",
      "count": 140
    },
    {
      "term": "Weakness",
      "count": 135
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 114
    },
    {
      "term": "Death",
      "count": 111
    },
    {
      "term": "Pacing",
      "count": 104
    },
    {
      "term": "Trembling",
      "count": 99
    },
    {
      "term": "Vocalisation",
      "count": 97
    },
    {
      "term": "Apprehension",
      "count": 83
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 81
    },
    {
      "term": "Elevated creatinine",
      "count": 77
    },
    {
      "term": "Aggression",
      "count": 76
    },
    {
      "term": "Anaemia NOS",
      "count": 71
    },
    {
      "term": "Accidental exposure",
      "count": 66
    },
    {
      "term": "Circling - neurological disorder (see also 'Behavioural disorders')",
      "count": 62
    },
    {
      "term": "No sign",
      "count": 62
    },
    {
      "term": "Pruritus",
      "count": 61
    },
    {
      "term": "Labelled drug-drug interaction medication error",
      "count": 55
    },
    {
      "term": "Collapse (see also 'Cardio-vascular' and 'Systemic disorders')",
      "count": 54
    },
    {
      "term": "Deafness",
      "count": 54
    },
    {
      "term": "Leucocytosis NOS",
      "count": 54
    },
    {
      "term": "Head tilt - ear disorder",
      "count": 51
    },
    {
      "term": "Hypersalivation",
      "count": 50
    },
    {
      "term": "Bloody diarrhoea",
      "count": 48
    },
    {
      "term": "Urinary incontinence",
      "count": 47
    },
    {
      "term": "Haematuria",
      "count": 46
    },
    {
      "term": "Hind limb paresis",
      "count": 46
    },
    {
      "term": "Dyspnoea",
      "count": 43
    },
    {
      "term": "Blindness",
      "count": 41
    },
    {
      "term": "Elevated liver enzymes",
      "count": 40
    },
    {
      "term": "Alopecia NOS",
      "count": 39
    },
    {
      "term": "Hyperglycaemia",
      "count": 38
    },
    {
      "term": "Vestibular disorder NOS",
      "count": 38
    },
    {
      "term": "Hyperkalaemia",
      "count": 37
    },
    {
      "term": "Fever",
      "count": 36
    },
    {
      "term": "Diabetes mellitus",
      "count": 33
    },
    {
      "term": "Stupor",
      "count": 33
    },
    {
      "term": "Seizure NOS",
      "count": 31
    },
    {
      "term": "Urinary tract infection",
      "count": 31
    },
    {
      "term": "Polyphagia",
      "count": 30
    },
    {
      "term": "Elevated cholesterol (total)",
      "count": 29
    },
    {
      "term": "Recumbency",
      "count": 29
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 28
    },
    {
      "term": "Proprioception abnormality",
      "count": 28
    },
    {
      "term": "Pyoderma",
      "count": 28
    },
    {
      "term": "Tachycardia",
      "count": 28
    },
    {
      "term": "Abdominal pain",
      "count": 27
    },
    {
      "term": "Decreased urine concentration",
      "count": 27
    },
    {
      "term": "Distension of abdomen",
      "count": 27
    },
    {
      "term": "Thrombocytopenia",
      "count": 27
    },
    {
      "term": "Elevated total bilirubin",
      "count": 26
    },
    {
      "term": "Excessive licking and/or grooming",
      "count": 26
    },
    {
      "term": "Twitching",
      "count": 26
    },
    {
      "term": "Nystagmus",
      "count": 25
    },
    {
      "term": "Reluctant to move",
      "count": 25
    },
    {
      "term": "Pancreatitis",
      "count": 24
    },
    {
      "term": "Shaking",
      "count": 24
    },
    {
      "term": "Urinary tract disorder NOS",
      "count": 24
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 23
    },
    {
      "term": "Epistaxis",
      "count": 23
    },
    {
      "term": "Loose stool",
      "count": 23
    },
    {
      "term": "Renal failure",
      "count": 23
    },
    {
      "term": "Elevated lipase",
      "count": 22
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 21
    },
    {
      "term": "Dehydration",
      "count": 21
    },
    {
      "term": "Disorientation",
      "count": 21
    },
    {
      "term": "Elevated amylase",
      "count": 21
    },
    {
      "term": "Melaena",
      "count": 21
    },
    {
      "term": "Overdose",
      "count": 21
    },
    {
      "term": "Proteinuria",
      "count": 21
    },
    {
      "term": "Urination",
      "count": 21
    },
    {
      "term": "Hypertension",
      "count": 20
    },
    {
      "term": "Underdose",
      "count": 20
    },
    {
      "term": "Hypothyroidism",
      "count": 19
    },
    {
      "term": "Partial deafness",
      "count": 19
    },
    {
      "term": "Staggering",
      "count": 19
    },
    {
      "term": "Dermatitis",
      "count": 18
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 18
    },
    {
      "term": "Sleep disturbance NOS",
      "count": 18
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 17
    },
    {
      "term": "Murmur",
      "count": 17
    },
    {
      "term": "Not sleeping",
      "count": 17
    }
  ]
}