{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Lack of efficacy - NOS",
      "count": 173
    },
    {
      "term": "Vomiting",
      "count": 34
    },
    {
      "term": "Tachycardia",
      "count": 27
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 23
    },
    {
      "term": "Sedation",
      "count": 17
    },
    {
      "term": "Hypersalivation",
      "count": 14
    },
    {
      "term": "Diarrhoea",
      "count": 12
    },
    {
      "term": "INEFFECTIVE, OTHER DRUG(S)",
      "count": 12
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 12
    },
    {
      "term": "Nausea",
      "count": 11
    },
    {
      "term": "Overdose",
      "count": 11
    },
    {
      "term": "Eye redness",
      "count": 10
    },
    {
      "term": "Retching",
      "count": 10
    },
    {
      "term": "Collapse NOS (see also Cardio-vascular and Neurological disorders)",
      "count": 8
    },
    {
      "term": "Partial lack of efficacy",
      "count": 8
    },
    {
      "term": "Drooling",
      "count": 7
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 7
    },
    {
      "term": "Third eyelid protrusion",
      "count": 7
    },
    {
      "term": "Death by euthanasia",
      "count": 6
    },
    {
      "term": "Decreased appetite",
      "count": 6
    },
    {
      "term": "Elevated total bilirubin",
      "count": 6
    },
    {
      "term": "INEFFECTIVE, ANTIEMETIC",
      "count": 6
    },
    {
      "term": "Lateral recumbency",
      "count": 6
    },
    {
      "term": "Malaise",
      "count": 6
    },
    {
      "term": "Ocular discharge",
      "count": 6
    },
    {
      "term": "Weakness",
      "count": 6
    },
    {
      "term": "Blepharospasm",
      "count": 5
    },
    {
      "term": "Gastrointestinal foreign body NOS",
      "count": 5
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 4
    },
    {
      "term": "Ataxia",
      "count": 4
    },
    {
      "term": "Collapse (see also Cardio-vascular and Systemic disorders)",
      "count": 4
    },
    {
      "term": "Conjunctival reddening",
      "count": 4
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 4
    },
    {
      "term": "Hypokalaemia",
      "count": 4
    },
    {
      "term": "Increased heart rate",
      "count": 4
    },
    {
      "term": "Lip licking",
      "count": 4
    },
    {
      "term": "Loose stool",
      "count": 4
    },
    {
      "term": "Panting",
      "count": 4
    },
    {
      "term": "Recumbency",
      "count": 4
    },
    {
      "term": "Sudden death",
      "count": 4
    },
    {
      "term": "Trembling",
      "count": 4
    },
    {
      "term": "Unable to stand",
      "count": 4
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 3
    },
    {
      "term": "Elevated amylase",
      "count": 3
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 3
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 3
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 3
    },
    {
      "term": "Elevated temperature",
      "count": 3
    },
    {
      "term": "Emesis",
      "count": 3
    },
    {
      "term": "Eyelid erythema",
      "count": 3
    },
    {
      "term": "Faecal incontinence",
      "count": 3
    },
    {
      "term": "Heavy breathing",
      "count": 3
    },
    {
      "term": "Hyperproteinaemia",
      "count": 3
    },
    {
      "term": "Hyperthermia",
      "count": 3
    },
    {
      "term": "Lymphopenia",
      "count": 3
    },
    {
      "term": "Muscle atrophy (see also Muscle wasting)",
      "count": 3
    },
    {
      "term": "Neurological disorder NOS",
      "count": 3
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 3
    },
    {
      "term": "Pale mucous membrane",
      "count": 3
    },
    {
      "term": "Proteinuria",
      "count": 3
    },
    {
      "term": "Shaking",
      "count": 3
    },
    {
      "term": "Stomach upset",
      "count": 3
    },
    {
      "term": "Tense abdomen",
      "count": 3
    },
    {
      "term": "Unable to walk",
      "count": 3
    },
    {
      "term": "Underdose",
      "count": 3
    },
    {
      "term": "Wobbliness",
      "count": 3
    },
    {
      "term": "Abdominal mass",
      "count": 2
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 2
    },
    {
      "term": "Abnormal stool colouration",
      "count": 2
    },
    {
      "term": "Accidental exposure",
      "count": 2
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 2
    },
    {
      "term": "Blood in vomit",
      "count": 2
    },
    {
      "term": "Conjunctivitis",
      "count": 2
    },
    {
      "term": "Constipation",
      "count": 2
    },
    {
      "term": "Cyanosis",
      "count": 2
    },
    {
      "term": "Death",
      "count": 2
    },
    {
      "term": "Decreased body temperature",
      "count": 2
    },
    {
      "term": "Decreased cholesterol (total)",
      "count": 2
    },
    {
      "term": "Decreased haematocrit",
      "count": 2
    },
    {
      "term": "Decreased haemoglobin",
      "count": 2
    },
    {
      "term": "Decreased pulse oxygenation",
      "count": 2
    },
    {
      "term": "Decreased red blood cell count",
      "count": 2
    },
    {
      "term": "Dental calculus",
      "count": 2
    },
    {
      "term": "Dull",
      "count": 2
    },
    {
      "term": "Ear infection NOS",
      "count": 2
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 2
    },
    {
      "term": "Elevated creatinine",
      "count": 2
    },
    {
      "term": "Elevated globulins",
      "count": 2
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 2
    },
    {
      "term": "Excessive thirst",
      "count": 2
    },
    {
      "term": "Eye irritation",
      "count": 2
    },
    {
      "term": "Eyelid oedema",
      "count": 2
    },
    {
      "term": "Flatulence",
      "count": 2
    },
    {
      "term": "Food refusal",
      "count": 2
    },
    {
      "term": "Gastric distension",
      "count": 2
    },
    {
      "term": "Haemorrhage NOS",
      "count": 2
    },
    {
      "term": "Head shake - behavioural disorder",
      "count": 2
    },
    {
      "term": "Hind limb paresis",
      "count": 2
    },
    {
      "term": "Hyperalbuminaemia",
      "count": 2
    },
    {
      "term": "Hypernatremia",
      "count": 2
    }
  ]
}