{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 397
    },
    {
      "term": "Not eating",
      "count": 394
    },
    {
      "term": "Anorexia",
      "count": 308
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 306
    },
    {
      "term": "Fever",
      "count": 304
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 294
    },
    {
      "term": "Death by euthanasia",
      "count": 286
    },
    {
      "term": "Vomiting",
      "count": 278
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 270
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 248
    },
    {
      "term": "Weight loss",
      "count": 223
    },
    {
      "term": "Death",
      "count": 222
    },
    {
      "term": "Decreased appetite",
      "count": 167
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 167
    },
    {
      "term": "Diarrhoea",
      "count": 160
    },
    {
      "term": "Dehydration",
      "count": 156
    },
    {
      "term": "Ataxia",
      "count": 155
    },
    {
      "term": "Not drinking",
      "count": 155
    },
    {
      "term": "Elevated creatinine",
      "count": 143
    },
    {
      "term": "Dilated pupils",
      "count": 142
    },
    {
      "term": "Hiding",
      "count": 141
    },
    {
      "term": "Vocalisation",
      "count": 128
    },
    {
      "term": "Hyperglycaemia",
      "count": 118
    },
    {
      "term": "Anaemia NOS",
      "count": 116
    },
    {
      "term": "Hyperactivity",
      "count": 116
    },
    {
      "term": "INEFFECTIVE, ANTIINFLAMMATORY",
      "count": 110
    },
    {
      "term": "Hyperphosphataemia",
      "count": 104
    },
    {
      "term": "Seizure NOS",
      "count": 100
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 96
    },
    {
      "term": "Pain NOS",
      "count": 95
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 93
    },
    {
      "term": "Hypothermia",
      "count": 93
    },
    {
      "term": "Dysphoria",
      "count": 88
    },
    {
      "term": "Elevated temperature",
      "count": 86
    },
    {
      "term": "Inappetence",
      "count": 86
    },
    {
      "term": "Hyperthermia",
      "count": 84
    },
    {
      "term": "Neutrophilia",
      "count": 80
    },
    {
      "term": "Hypersalivation",
      "count": 74
    },
    {
      "term": "Not sleeping",
      "count": 72
    },
    {
      "term": "Constipation",
      "count": 71
    },
    {
      "term": "INEFFECTIVE, ANALGESIA",
      "count": 68
    },
    {
      "term": "Leucocytosis NOS",
      "count": 67
    },
    {
      "term": "Lateral recumbency",
      "count": 64
    },
    {
      "term": "Elevated total bilirubin",
      "count": 63
    },
    {
      "term": "Drooling",
      "count": 62
    },
    {
      "term": "Emesis",
      "count": 60
    },
    {
      "term": "Limping",
      "count": 59
    },
    {
      "term": "Reluctant to move",
      "count": 59
    },
    {
      "term": "Lymphopenia",
      "count": 58
    },
    {
      "term": "Agitation",
      "count": 57
    },
    {
      "term": "Malaise",
      "count": 57
    },
    {
      "term": "Proteinuria",
      "count": 57
    },
    {
      "term": "Emesis (multiple)",
      "count": 56
    },
    {
      "term": "Tachypnoea",
      "count": 56
    },
    {
      "term": "Surgical site disorder",
      "count": 55
    },
    {
      "term": "Restlessness",
      "count": 54
    },
    {
      "term": "Elevated globulins",
      "count": 53
    },
    {
      "term": "Weakness",
      "count": 53
    },
    {
      "term": "Inappropriate urination",
      "count": 52
    },
    {
      "term": "Intentional misuse",
      "count": 52
    },
    {
      "term": "Twitching",
      "count": 52
    },
    {
      "term": "Adipsia",
      "count": 51
    },
    {
      "term": "Thrombocytopenia",
      "count": 51
    },
    {
      "term": "Panting",
      "count": 50
    },
    {
      "term": "Hyperproteinaemia",
      "count": 49
    },
    {
      "term": "Pale mucous membrane",
      "count": 49
    },
    {
      "term": "Application site hair loss",
      "count": 47
    },
    {
      "term": "Neutropenia",
      "count": 47
    },
    {
      "term": "Open mouth breathing",
      "count": 47
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 46
    },
    {
      "term": "Cardiac arrest",
      "count": 46
    },
    {
      "term": "Decreased body temperature",
      "count": 45
    },
    {
      "term": "Skin scab",
      "count": 45
    },
    {
      "term": "Tachycardia",
      "count": 45
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 43
    },
    {
      "term": "Blood in urine",
      "count": 42
    },
    {
      "term": "Haematuria",
      "count": 42
    },
    {
      "term": "Renal failure",
      "count": 41
    },
    {
      "term": "Monocytosis",
      "count": 40
    },
    {
      "term": "Walking difficulty",
      "count": 40
    },
    {
      "term": "Falling",
      "count": 39
    },
    {
      "term": "Heart murmur",
      "count": 39
    },
    {
      "term": "Application site alopecia",
      "count": 38
    },
    {
      "term": "Eosinopenia",
      "count": 38
    },
    {
      "term": "Not himself/herself",
      "count": 38
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 37
    },
    {
      "term": "Loose stool",
      "count": 37
    },
    {
      "term": "Not urinating",
      "count": 37
    },
    {
      "term": "Sleepiness - systemic disorder",
      "count": 37
    },
    {
      "term": "Blindness",
      "count": 36
    },
    {
      "term": "Mydriasis",
      "count": 36
    },
    {
      "term": "Urine abnormalities NOS",
      "count": 36
    },
    {
      "term": "Acute renal failure",
      "count": 35
    },
    {
      "term": "Azotaemia",
      "count": 35
    },
    {
      "term": "Decreased packed cell volume (PCV)",
      "count": 35
    },
    {
      "term": "Decreased urine concentration",
      "count": 35
    },
    {
      "term": "Increased respiratory rate",
      "count": 35
    },
    {
      "term": "Low platelet count",
      "count": 35
    },
    {
      "term": "Aggression",
      "count": 34
    },
    {
      "term": "Depression",
      "count": 34
    }
  ]
}