{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Death",
      "count": 463
    },
    {
      "term": "Vomiting",
      "count": 307
    },
    {
      "term": "Bradycardia",
      "count": 294
    },
    {
      "term": "Cardiac arrest",
      "count": 273
    },
    {
      "term": "INEFFECTIVE, ANESTHESIA",
      "count": 273
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 231
    },
    {
      "term": "Apnoea",
      "count": 225
    },
    {
      "term": "Seizure NOS",
      "count": 180
    },
    {
      "term": "Diarrhoea",
      "count": 161
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 153
    },
    {
      "term": "Anorexia",
      "count": 148
    },
    {
      "term": "Death by euthanasia",
      "count": 143
    },
    {
      "term": "Tachycardia",
      "count": 139
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 116
    },
    {
      "term": "Pale mucous membrane",
      "count": 113
    },
    {
      "term": "Cyanosis",
      "count": 110
    },
    {
      "term": "Convulsion",
      "count": 109
    },
    {
      "term": "Not eating",
      "count": 109
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 107
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 107
    },
    {
      "term": "Hypotension",
      "count": 103
    },
    {
      "term": "Fever",
      "count": 102
    },
    {
      "term": "Vocalisation",
      "count": 92
    },
    {
      "term": "Panting",
      "count": 89
    },
    {
      "term": "Anaphylaxis",
      "count": 88
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 86
    },
    {
      "term": "Injection site swelling",
      "count": 85
    },
    {
      "term": "Decreased appetite",
      "count": 84
    },
    {
      "term": "Elevated total bilirubin",
      "count": 83
    },
    {
      "term": "Leucocytosis NOS",
      "count": 81
    },
    {
      "term": "Recovery prolonged",
      "count": 81
    },
    {
      "term": "Hypothermia",
      "count": 78
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 74
    },
    {
      "term": "Twitching",
      "count": 71
    },
    {
      "term": "Bloody diarrhoea",
      "count": 70
    },
    {
      "term": "Pain NOS",
      "count": 70
    },
    {
      "term": "Paddling",
      "count": 69
    },
    {
      "term": "Ataxia",
      "count": 66
    },
    {
      "term": "Elevated creatinine",
      "count": 66
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 64
    },
    {
      "term": "Facial swelling (see also 'Skin')",
      "count": 63
    },
    {
      "term": "Hypersalivation",
      "count": 63
    },
    {
      "term": "Tachypnoea",
      "count": 63
    },
    {
      "term": "Weight loss",
      "count": 62
    },
    {
      "term": "Neutrophilia",
      "count": 59
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 57
    },
    {
      "term": "Depression",
      "count": 56
    },
    {
      "term": "Hyperexcitation",
      "count": 54
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 54
    },
    {
      "term": "Tremor",
      "count": 53
    },
    {
      "term": "Regurgitation",
      "count": 52
    },
    {
      "term": "Anaemia NOS",
      "count": 51
    },
    {
      "term": "Nystagmus",
      "count": 51
    },
    {
      "term": "Thrombocytopenia",
      "count": 51
    },
    {
      "term": "Arrhythmia",
      "count": 50
    },
    {
      "term": "Dehydration",
      "count": 50
    },
    {
      "term": "Emesis",
      "count": 50
    },
    {
      "term": "Hyperphosphataemia",
      "count": 49
    },
    {
      "term": "Hives (see also 'Skin')",
      "count": 48
    },
    {
      "term": "Elevated liver enzymes",
      "count": 46
    },
    {
      "term": "Bruising",
      "count": 43
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 43
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 42
    },
    {
      "term": "Dyspnoea",
      "count": 41
    },
    {
      "term": "Trembling",
      "count": 41
    },
    {
      "term": "Hyperglycaemia",
      "count": 40
    },
    {
      "term": "Icterus",
      "count": 40
    },
    {
      "term": "Weakness",
      "count": 40
    },
    {
      "term": "Hypoproteinaemia",
      "count": 39
    },
    {
      "term": "Lameness",
      "count": 39
    },
    {
      "term": "Respiratory arrest",
      "count": 39
    },
    {
      "term": "Underdose",
      "count": 39
    },
    {
      "term": "Abdominal pain",
      "count": 38
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 38
    },
    {
      "term": "Monocytosis",
      "count": 38
    },
    {
      "term": "Overdose",
      "count": 38
    },
    {
      "term": "Heart block NOS",
      "count": 37
    },
    {
      "term": "Hypoglycaemia",
      "count": 37
    },
    {
      "term": "Shaking",
      "count": 37
    },
    {
      "term": "Swelling NOS",
      "count": 37
    },
    {
      "term": "Inappetence",
      "count": 36
    },
    {
      "term": "Decreased heart rate",
      "count": 35
    },
    {
      "term": "Injection site pain",
      "count": 34
    },
    {
      "term": "Leucopenia NOS",
      "count": 33
    },
    {
      "term": "Neutropenia",
      "count": 33
    },
    {
      "term": "Opisthotonus",
      "count": 33
    },
    {
      "term": "Rigidity of limbs",
      "count": 33
    },
    {
      "term": "Wound",
      "count": 33
    },
    {
      "term": "Hyperactivity",
      "count": 32
    },
    {
      "term": "Abnormal breathing",
      "count": 31
    },
    {
      "term": "Facial swelling (see also Skin)",
      "count": 31
    },
    {
      "term": "Prolonged anaesthesia",
      "count": 31
    },
    {
      "term": "Drooling",
      "count": 30
    },
    {
      "term": "Lateral recumbency",
      "count": 30
    },
    {
      "term": "Hyperthermia",
      "count": 29
    },
    {
      "term": "Intestinal perforation",
      "count": 29
    },
    {
      "term": "Polydipsia",
      "count": 29
    },
    {
      "term": "Cough",
      "count": 28
    },
    {
      "term": "Polyuria",
      "count": 28
    },
    {
      "term": "Hypertension",
      "count": 27
    }
  ]
}