{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Lack of efficacy - NOS",
      "count": 34
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 20
    },
    {
      "term": "Ataxia",
      "count": 18
    },
    {
      "term": "Overdose",
      "count": 14
    },
    {
      "term": "Wobbliness",
      "count": 13
    },
    {
      "term": "Sedation",
      "count": 10
    },
    {
      "term": "Intentional misuse",
      "count": 9
    },
    {
      "term": "Medication error NOS",
      "count": 9
    },
    {
      "term": "Partial lack of efficacy",
      "count": 9
    },
    {
      "term": "Vomiting",
      "count": 8
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 6
    },
    {
      "term": "Death by euthanasia",
      "count": 6
    },
    {
      "term": "Diarrhoea",
      "count": 6
    },
    {
      "term": "Not himself/herself",
      "count": 6
    },
    {
      "term": "Bradycardia",
      "count": 5
    },
    {
      "term": "Sedation prolonged",
      "count": 5
    },
    {
      "term": "Abnormal breathing",
      "count": 4
    },
    {
      "term": "Decreased appetite",
      "count": 4
    },
    {
      "term": "Drooling",
      "count": 4
    },
    {
      "term": "Hiding",
      "count": 4
    },
    {
      "term": "Hyperglycaemia",
      "count": 4
    },
    {
      "term": "Quiet",
      "count": 4
    },
    {
      "term": "Seizure NOS",
      "count": 4
    },
    {
      "term": "Walking difficulty",
      "count": 4
    },
    {
      "term": "Weakness",
      "count": 4
    },
    {
      "term": "Aggression",
      "count": 3
    },
    {
      "term": "Dazed",
      "count": 3
    },
    {
      "term": "Dilated pupils",
      "count": 3
    },
    {
      "term": "Disorientation",
      "count": 3
    },
    {
      "term": "Emesis (multiple)",
      "count": 3
    },
    {
      "term": "Stumbling gait",
      "count": 3
    },
    {
      "term": "Tachycardia",
      "count": 3
    },
    {
      "term": "Tremor",
      "count": 3
    },
    {
      "term": "Twitching",
      "count": 3
    },
    {
      "term": "Underdose",
      "count": 3
    },
    {
      "term": "Vocalisation",
      "count": 3
    },
    {
      "term": "Abnormal tail posture",
      "count": 2
    },
    {
      "term": "Alopecia local",
      "count": 2
    },
    {
      "term": "Anaemia NOS",
      "count": 2
    },
    {
      "term": "Anorexia",
      "count": 2
    },
    {
      "term": "Breathing difficulty",
      "count": 2
    },
    {
      "term": "Cough",
      "count": 2
    },
    {
      "term": "Dehydration",
      "count": 2
    },
    {
      "term": "Difficulty standing",
      "count": 2
    },
    {
      "term": "Drunken gait",
      "count": 2
    },
    {
      "term": "Facial pruritus",
      "count": 2
    },
    {
      "term": "Falling",
      "count": 2
    },
    {
      "term": "Foaming at the mouth",
      "count": 2
    },
    {
      "term": "Frequent urination",
      "count": 2
    },
    {
      "term": "Head pressing",
      "count": 2
    },
    {
      "term": "Heart murmur",
      "count": 2
    },
    {
      "term": "Hyperactivity",
      "count": 2
    },
    {
      "term": "Hypoglycaemia",
      "count": 2
    },
    {
      "term": "Incoordination",
      "count": 2
    },
    {
      "term": "Increased appetite",
      "count": 2
    },
    {
      "term": "Inflammatory bowel disorder",
      "count": 2
    },
    {
      "term": "Injection site lump",
      "count": 2
    },
    {
      "term": "Irregular pulse",
      "count": 2
    },
    {
      "term": "Limb weakness",
      "count": 2
    },
    {
      "term": "Limping",
      "count": 2
    },
    {
      "term": "Musculoskeletal disorder NOS",
      "count": 2
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 2
    },
    {
      "term": "Pacing",
      "count": 2
    },
    {
      "term": "Plantigrade posture",
      "count": 2
    },
    {
      "term": "Proprioception deficit",
      "count": 2
    },
    {
      "term": "Pruritus",
      "count": 2
    },
    {
      "term": "Sleepiness - systemic disorder",
      "count": 2
    },
    {
      "term": "Sneezing",
      "count": 2
    },
    {
      "term": "Spindle cell tumour",
      "count": 2
    },
    {
      "term": "Unable to jump",
      "count": 2
    },
    {
      "term": "Unkempt hair coat",
      "count": 2
    },
    {
      "term": "Abnormal menace reflex test",
      "count": 1
    },
    {
      "term": "Abnormal movement NOS",
      "count": 1
    },
    {
      "term": "Abnormal posture NOS",
      "count": 1
    },
    {
      "term": "Abnormal pupil light reflex",
      "count": 1
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 1
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 1
    },
    {
      "term": "Accidental exposure",
      "count": 1
    },
    {
      "term": "Acute renal failure",
      "count": 1
    },
    {
      "term": "Adrenal gland disorder NOS",
      "count": 1
    },
    {
      "term": "Agitation",
      "count": 1
    },
    {
      "term": "Apnoea",
      "count": 1
    },
    {
      "term": "Appetite disorder NOS",
      "count": 1
    },
    {
      "term": "Arrhythmia",
      "count": 1
    },
    {
      "term": "Balance impaired",
      "count": 1
    },
    {
      "term": "Basophilia",
      "count": 1
    },
    {
      "term": "Biting -aggression (see also Skin and appendages disorders)",
      "count": 1
    },
    {
      "term": "Blood in vomit",
      "count": 1
    },
    {
      "term": "Bone and joint disorder NOS",
      "count": 1
    },
    {
      "term": "Bronchopulmonary inflammation",
      "count": 1
    },
    {
      "term": "Bumping into walls",
      "count": 1
    },
    {
      "term": "Cardiac enlargement",
      "count": 1
    },
    {
      "term": "Cardiac murmur",
      "count": 1
    },
    {
      "term": "Cold feeling to the touch",
      "count": 1
    },
    {
      "term": "Conjunctivitis",
      "count": 1
    },
    {
      "term": "Constipation",
      "count": 1
    },
    {
      "term": "Corneal disorder NOS",
      "count": 1
    },
    {
      "term": "Crust",
      "count": 1
    },
    {
      "term": "Cyanosis",
      "count": 1
    },
    {
      "term": "Cyanotic mucous membranes",
      "count": 1
    }
  ]
}