{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 692
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 520
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 449
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 340
    },
    {
      "term": "Anorexia",
      "count": 305
    },
    {
      "term": "Death by euthanasia",
      "count": 300
    },
    {
      "term": "Diarrhoea",
      "count": 290
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 260
    },
    {
      "term": "Seizure NOS",
      "count": 251
    },
    {
      "term": "Emesis",
      "count": 224
    },
    {
      "term": "Death",
      "count": 221
    },
    {
      "term": "Leucocytosis NOS",
      "count": 214
    },
    {
      "term": "Decreased appetite",
      "count": 210
    },
    {
      "term": "Not eating",
      "count": 206
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 193
    },
    {
      "term": "Fever",
      "count": 186
    },
    {
      "term": "Lack of efficacy (bacteria) - NOS",
      "count": 170
    },
    {
      "term": "Anaemia NOS",
      "count": 168
    },
    {
      "term": "Ataxia",
      "count": 166
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 163
    },
    {
      "term": "Weight loss",
      "count": 158
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 154
    },
    {
      "term": "Neutrophilia",
      "count": 152
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 137
    },
    {
      "term": "Elevated total bilirubin",
      "count": 134
    },
    {
      "term": "Urinary tract infection",
      "count": 131
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 127
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 115
    },
    {
      "term": "Polydipsia",
      "count": 111
    },
    {
      "term": "Elevated liver enzymes",
      "count": 109
    },
    {
      "term": "Dehydration",
      "count": 107
    },
    {
      "term": "Thrombocytopenia",
      "count": 107
    },
    {
      "term": "Cough",
      "count": 106
    },
    {
      "term": "Panting",
      "count": 104
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 99
    },
    {
      "term": "Polyuria",
      "count": 96
    },
    {
      "term": "Pale mucous membrane",
      "count": 90
    },
    {
      "term": "Pain NOS",
      "count": 89
    },
    {
      "term": "Hyperphosphataemia",
      "count": 86
    },
    {
      "term": "Inappetence",
      "count": 86
    },
    {
      "term": "Proteinuria",
      "count": 83
    },
    {
      "term": "Elevated creatinine",
      "count": 82
    },
    {
      "term": "Pruritus",
      "count": 82
    },
    {
      "term": "Weakness",
      "count": 81
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 80
    },
    {
      "term": "Shaking",
      "count": 80
    },
    {
      "term": "Vocalisation",
      "count": 79
    },
    {
      "term": "Hyperglycaemia",
      "count": 72
    },
    {
      "term": "Skin lesion NOS",
      "count": 72
    },
    {
      "term": "Monocytosis",
      "count": 71
    },
    {
      "term": "Overdose",
      "count": 71
    },
    {
      "term": "Urinary incontinence",
      "count": 70
    },
    {
      "term": "Urine abnormalities NOS",
      "count": 69
    },
    {
      "term": "Emesis (multiple)",
      "count": 68
    },
    {
      "term": "Intentional misuse",
      "count": 68
    },
    {
      "term": "Reluctant to move",
      "count": 67
    },
    {
      "term": "Abnormal cytology",
      "count": 64
    },
    {
      "term": "Leucopenia NOS",
      "count": 64
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 62
    },
    {
      "term": "Facial swelling (see also 'Skin')",
      "count": 59
    },
    {
      "term": "Haematuria",
      "count": 59
    },
    {
      "term": "Hypoproteinaemia",
      "count": 58
    },
    {
      "term": "Lymphopenia",
      "count": 58
    },
    {
      "term": "Bloody diarrhoea",
      "count": 57
    },
    {
      "term": "Underdose",
      "count": 57
    },
    {
      "term": "Walking difficulty",
      "count": 56
    },
    {
      "term": "Nasal discharge",
      "count": 55
    },
    {
      "term": "Icterus",
      "count": 54
    },
    {
      "term": "Tachycardia",
      "count": 54
    },
    {
      "term": "Hypoglycaemia",
      "count": 53
    },
    {
      "term": "Loose stool",
      "count": 53
    },
    {
      "term": "Ocular discharge",
      "count": 53
    },
    {
      "term": "Blood in urine",
      "count": 52
    },
    {
      "term": "Localised pain NOS (see other 'SOCs' for specific pain)",
      "count": 52
    },
    {
      "term": "Limb weakness",
      "count": 51
    },
    {
      "term": "Restlessness",
      "count": 50
    },
    {
      "term": "Decreased packed cell volume (PCV)",
      "count": 49
    },
    {
      "term": "Hypokalaemia",
      "count": 49
    },
    {
      "term": "INEFFECTIVE, ANTIBIOTIC",
      "count": 48
    },
    {
      "term": "Inappropriate urination",
      "count": 48
    },
    {
      "term": "Lameness",
      "count": 48
    },
    {
      "term": "Unable to stand",
      "count": 48
    },
    {
      "term": "Abdominal pain",
      "count": 47
    },
    {
      "term": "Bruising",
      "count": 47
    },
    {
      "term": "Depression",
      "count": 47
    },
    {
      "term": "Disorientation",
      "count": 47
    },
    {
      "term": "Anxiety",
      "count": 46
    },
    {
      "term": "Hyperkalaemia",
      "count": 46
    },
    {
      "term": "Lateral recumbency",
      "count": 46
    },
    {
      "term": "Pneumonia",
      "count": 46
    },
    {
      "term": "Sneezing",
      "count": 46
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 45
    },
    {
      "term": "Injection site swelling",
      "count": 45
    },
    {
      "term": "Elevated renal parameters",
      "count": 44
    },
    {
      "term": "Heart murmur",
      "count": 44
    },
    {
      "term": "Hyponatremia",
      "count": 44
    },
    {
      "term": "Low platelet count",
      "count": 44
    },
    {
      "term": "Medication error NOS",
      "count": 44
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 43
    },
    {
      "term": "Laboured breathing",
      "count": 43
    }
  ]
}