{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 294
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 169
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 147
    },
    {
      "term": "Diarrhoea",
      "count": 145
    },
    {
      "term": "Anorexia",
      "count": 144
    },
    {
      "term": "Death by euthanasia",
      "count": 125
    },
    {
      "term": "Death",
      "count": 118
    },
    {
      "term": "Weight loss",
      "count": 116
    },
    {
      "term": "Not eating",
      "count": 104
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 94
    },
    {
      "term": "Decreased appetite",
      "count": 84
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 84
    },
    {
      "term": "Ataxia",
      "count": 81
    },
    {
      "term": "Dehydration",
      "count": 80
    },
    {
      "term": "Lack of efficacy (bacteria) - NOS",
      "count": 80
    },
    {
      "term": "Anaemia NOS",
      "count": 69
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 69
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 64
    },
    {
      "term": "Fever",
      "count": 64
    },
    {
      "term": "Hyperglycaemia",
      "count": 63
    },
    {
      "term": "Elevated creatinine",
      "count": 54
    },
    {
      "term": "Hypokalaemia",
      "count": 51
    },
    {
      "term": "Vocalisation",
      "count": 51
    },
    {
      "term": "Emesis",
      "count": 50
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 45
    },
    {
      "term": "Hiding",
      "count": 44
    },
    {
      "term": "Hypothermia",
      "count": 44
    },
    {
      "term": "Leucocytosis NOS",
      "count": 44
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 43
    },
    {
      "term": "Seizure NOS",
      "count": 42
    },
    {
      "term": "Inappetence",
      "count": 41
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 39
    },
    {
      "term": "Not drinking",
      "count": 39
    },
    {
      "term": "Neutrophilia",
      "count": 38
    },
    {
      "term": "Intentional misuse",
      "count": 37
    },
    {
      "term": "Hypersalivation",
      "count": 36
    },
    {
      "term": "Overdose",
      "count": 36
    },
    {
      "term": "Urinary tract infection",
      "count": 35
    },
    {
      "term": "Drooling",
      "count": 33
    },
    {
      "term": "Hyperphosphataemia",
      "count": 32
    },
    {
      "term": "Proteinuria",
      "count": 32
    },
    {
      "term": "Weakness",
      "count": 32
    },
    {
      "term": "Pale mucous membrane",
      "count": 31
    },
    {
      "term": "Decreased haematocrit",
      "count": 29
    },
    {
      "term": "Inappropriate urination",
      "count": 27
    },
    {
      "term": "Ketosis",
      "count": 27
    },
    {
      "term": "Underdose",
      "count": 27
    },
    {
      "term": "Blood in urine",
      "count": 26
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 26
    },
    {
      "term": "Elevated total bilirubin",
      "count": 26
    },
    {
      "term": "Dilated pupils",
      "count": 25
    },
    {
      "term": "Polydipsia",
      "count": 24
    },
    {
      "term": "Adipsia",
      "count": 23
    },
    {
      "term": "Loose stool",
      "count": 23
    },
    {
      "term": "Nasal discharge",
      "count": 23
    },
    {
      "term": "Open mouth breathing",
      "count": 23
    },
    {
      "term": "Pruritus",
      "count": 23
    },
    {
      "term": "Sneezing",
      "count": 23
    },
    {
      "term": "Tachypnoea",
      "count": 23
    },
    {
      "term": "Color, Abnormal",
      "count": 22
    },
    {
      "term": "Elevated globulins",
      "count": 22
    },
    {
      "term": "Foaming at the mouth",
      "count": 22
    },
    {
      "term": "Lateral recumbency",
      "count": 22
    },
    {
      "term": "Constipation",
      "count": 21
    },
    {
      "term": "Heart murmur",
      "count": 21
    },
    {
      "term": "Hypoglycaemia",
      "count": 21
    },
    {
      "term": "Hypotension",
      "count": 21
    },
    {
      "term": "INEFFECTIVE, ANTIBIOTIC",
      "count": 21
    },
    {
      "term": "Tachycardia",
      "count": 21
    },
    {
      "term": "Breathing difficulty",
      "count": 20
    },
    {
      "term": "Emesis (multiple)",
      "count": 20
    },
    {
      "term": "Falling",
      "count": 20
    },
    {
      "term": "Pain NOS",
      "count": 20
    },
    {
      "term": "Skin lesion NOS",
      "count": 20
    },
    {
      "term": "Urine abnormalities NOS",
      "count": 20
    },
    {
      "term": "Reluctant to move",
      "count": 19
    },
    {
      "term": "Gait abnormality",
      "count": 18
    },
    {
      "term": "Polyuria",
      "count": 18
    },
    {
      "term": "Thrombocytopenia",
      "count": 18
    },
    {
      "term": "Urinary bladder disorder NOS",
      "count": 18
    },
    {
      "term": "Cough",
      "count": 17
    },
    {
      "term": "Decreased packed cell volume (PCV)",
      "count": 17
    },
    {
      "term": "Elevated liver enzymes",
      "count": 17
    },
    {
      "term": "Glucosuria",
      "count": 17
    },
    {
      "term": "Hypochloraemia",
      "count": 17
    },
    {
      "term": "Blindness",
      "count": 16
    },
    {
      "term": "Depression",
      "count": 16
    },
    {
      "term": "Haematuria",
      "count": 16
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 16
    },
    {
      "term": "Increased respiratory rate",
      "count": 16
    },
    {
      "term": "Neurological signs NOS",
      "count": 16
    },
    {
      "term": "Renal disorder NOS",
      "count": 16
    },
    {
      "term": "Anisocoria",
      "count": 15
    },
    {
      "term": "Azotaemia",
      "count": 15
    },
    {
      "term": "Cardiac arrest",
      "count": 15
    },
    {
      "term": "Disorientation",
      "count": 15
    },
    {
      "term": "Dyspnoea",
      "count": 15
    },
    {
      "term": "Elevated cholesterol (total)",
      "count": 15
    },
    {
      "term": "Musculoskeletal disorder NOS",
      "count": 15
    },
    {
      "term": "Nausea",
      "count": 15
    }
  ]
}