{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 1000
    },
    {
      "term": "Diarrhoea",
      "count": 729
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 516
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 477
    },
    {
      "term": "Not eating",
      "count": 352
    },
    {
      "term": "Death by euthanasia",
      "count": 266
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 227
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 223
    },
    {
      "term": "Anorexia",
      "count": 204
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 203
    },
    {
      "term": "Weight loss",
      "count": 195
    },
    {
      "term": "Decreased appetite",
      "count": 177
    },
    {
      "term": "Bloody diarrhoea",
      "count": 160
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 151
    },
    {
      "term": "Panting",
      "count": 140
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 134
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 128
    },
    {
      "term": "Death",
      "count": 127
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 121
    },
    {
      "term": "Seizure NOS",
      "count": 117
    },
    {
      "term": "Emesis",
      "count": 112
    },
    {
      "term": "Pain NOS",
      "count": 112
    },
    {
      "term": "Elevated creatinine",
      "count": 110
    },
    {
      "term": "Limb weakness",
      "count": 107
    },
    {
      "term": "Incorrect route of drug administration",
      "count": 103
    },
    {
      "term": "Anaemia NOS",
      "count": 90
    },
    {
      "term": "Weakness",
      "count": 90
    },
    {
      "term": "Dehydration",
      "count": 87
    },
    {
      "term": "Nausea",
      "count": 84
    },
    {
      "term": "Loose stool",
      "count": 83
    },
    {
      "term": "Polydipsia",
      "count": 83
    },
    {
      "term": "Polyuria",
      "count": 83
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 82
    },
    {
      "term": "Ataxia",
      "count": 81
    },
    {
      "term": "Emesis (multiple)",
      "count": 79
    },
    {
      "term": "Inappetence",
      "count": 79
    },
    {
      "term": "Lameness",
      "count": 73
    },
    {
      "term": "Elevated liver enzymes",
      "count": 70
    },
    {
      "term": "Anaphylaxis",
      "count": 68
    },
    {
      "term": "INEFFECTIVE, OTHER DRUG(S)",
      "count": 68
    },
    {
      "term": "Walking difficulty",
      "count": 67
    },
    {
      "term": "Injection site pain",
      "count": 63
    },
    {
      "term": "Low platelet count",
      "count": 63
    },
    {
      "term": "Neutrophilia",
      "count": 63
    },
    {
      "term": "Not drinking",
      "count": 63
    },
    {
      "term": "Drooling",
      "count": 62
    },
    {
      "term": "Leucocytosis NOS",
      "count": 62
    },
    {
      "term": "Shaking",
      "count": 62
    },
    {
      "term": "Vocalisation",
      "count": 62
    },
    {
      "term": "Restlessness",
      "count": 61
    },
    {
      "term": "Urinary incontinence",
      "count": 61
    },
    {
      "term": "Fever",
      "count": 60
    },
    {
      "term": "Pale mucous membrane",
      "count": 60
    },
    {
      "term": "Reluctant to move",
      "count": 58
    },
    {
      "term": "Anxiety",
      "count": 57
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 57
    },
    {
      "term": "Product Defect, General",
      "count": 57
    },
    {
      "term": "Partial lack of efficacy",
      "count": 55
    },
    {
      "term": "Proteinuria",
      "count": 55
    },
    {
      "term": "Urinary tract infection",
      "count": 55
    },
    {
      "term": "Musculoskeletal disorder NOS",
      "count": 52
    },
    {
      "term": "Arthritis",
      "count": 50
    },
    {
      "term": "Thrombocytopenia",
      "count": 49
    },
    {
      "term": "Appetite loss",
      "count": 48
    },
    {
      "term": "Elevated total bilirubin",
      "count": 48
    },
    {
      "term": "Falling",
      "count": 48
    },
    {
      "term": "Cough",
      "count": 47
    },
    {
      "term": "Depression",
      "count": 47
    },
    {
      "term": "Limping",
      "count": 47
    },
    {
      "term": "Hyperphosphataemia",
      "count": 46
    },
    {
      "term": "Inappropriate urination",
      "count": 46
    },
    {
      "term": "Decreased packed cell volume (PCV)",
      "count": 45
    },
    {
      "term": "Recumbency",
      "count": 45
    },
    {
      "term": "Unable to stand",
      "count": 45
    },
    {
      "term": "Proprioception deficit",
      "count": 44
    },
    {
      "term": "Bone and joint disorder NOS",
      "count": 43
    },
    {
      "term": "Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders')",
      "count": 43
    },
    {
      "term": "Elevated cholesterol (total)",
      "count": 43
    },
    {
      "term": "Uncomfortable",
      "count": 43
    },
    {
      "term": "Malaise",
      "count": 42
    },
    {
      "term": "Lymphopenia",
      "count": 40
    },
    {
      "term": "Unable to rise",
      "count": 40
    },
    {
      "term": "Abdominal pain",
      "count": 38
    },
    {
      "term": "Disorientation",
      "count": 38
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 38
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 37
    },
    {
      "term": "Bruising",
      "count": 35
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 35
    },
    {
      "term": "Elevated lipase",
      "count": 35
    },
    {
      "term": "Inappropriate schedule of drug administration",
      "count": 35
    },
    {
      "term": "Blood in vomit",
      "count": 33
    },
    {
      "term": "Partial anorexia",
      "count": 33
    },
    {
      "term": "Decreased urine concentration",
      "count": 32
    },
    {
      "term": "Drinking a lot",
      "count": 32
    },
    {
      "term": "Hyperglycaemia",
      "count": 32
    },
    {
      "term": "Weight gain",
      "count": 32
    },
    {
      "term": "Knuckling",
      "count": 31
    },
    {
      "term": "Pancreatitis",
      "count": 31
    },
    {
      "term": "Tachycardia",
      "count": 30
    },
    {
      "term": "Thrombocytosis",
      "count": 30
    }
  ]
}