{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 899
    },
    {
      "term": "Diarrhoea",
      "count": 832
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 445
    },
    {
      "term": "Cough",
      "count": 407
    },
    {
      "term": "Death",
      "count": 393
    },
    {
      "term": "Anorexia",
      "count": 357
    },
    {
      "term": "Death by euthanasia",
      "count": 352
    },
    {
      "term": "Seizure NOS",
      "count": 229
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 220
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 211
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 208
    },
    {
      "term": "Decreased appetite",
      "count": 205
    },
    {
      "term": "Accidental exposure",
      "count": 196
    },
    {
      "term": "Not eating",
      "count": 190
    },
    {
      "term": "Ataxia",
      "count": 186
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 180
    },
    {
      "term": "Weight loss",
      "count": 174
    },
    {
      "term": "Tachycardia",
      "count": 169
    },
    {
      "term": "Overdose",
      "count": 160
    },
    {
      "term": "Panting",
      "count": 153
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 140
    },
    {
      "term": "Polydipsia",
      "count": 130
    },
    {
      "term": "Elevated creatinine",
      "count": 128
    },
    {
      "term": "Depression",
      "count": 123
    },
    {
      "term": "Polyuria",
      "count": 118
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 117
    },
    {
      "term": "Shaking",
      "count": 115
    },
    {
      "term": "Restlessness",
      "count": 110
    },
    {
      "term": "Loose stool",
      "count": 107
    },
    {
      "term": "Syncope",
      "count": 104
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 98
    },
    {
      "term": "Underdose",
      "count": 95
    },
    {
      "term": "Inappetence",
      "count": 90
    },
    {
      "term": "Vocalisation",
      "count": 85
    },
    {
      "term": "Weakness",
      "count": 85
    },
    {
      "term": "Arrhythmia",
      "count": 82
    },
    {
      "term": "Trembling",
      "count": 80
    },
    {
      "term": "Dyspnoea",
      "count": 79
    },
    {
      "term": "Pruritus",
      "count": 79
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 78
    },
    {
      "term": "Urinary incontinence",
      "count": 77
    },
    {
      "term": "Increased respiratory rate",
      "count": 76
    },
    {
      "term": "Emesis",
      "count": 73
    },
    {
      "term": "Urinary tract infection",
      "count": 71
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 68
    },
    {
      "term": "Tachypnoea",
      "count": 67
    },
    {
      "term": "Bloody diarrhoea",
      "count": 65
    },
    {
      "term": "Hyperphosphataemia",
      "count": 63
    },
    {
      "term": "Hyperkalaemia",
      "count": 62
    },
    {
      "term": "Emesis (multiple)",
      "count": 61
    },
    {
      "term": "Cardiac enlargement",
      "count": 60
    },
    {
      "term": "Congestive heart failure",
      "count": 59
    },
    {
      "term": "Increased heart rate",
      "count": 59
    },
    {
      "term": "Pain NOS",
      "count": 59
    },
    {
      "term": "Convulsion",
      "count": 56
    },
    {
      "term": "Falling",
      "count": 56
    },
    {
      "term": "Inappropriate urination",
      "count": 56
    },
    {
      "term": "Breathing difficulty",
      "count": 55
    },
    {
      "term": "Laboured breathing",
      "count": 55
    },
    {
      "term": "Anxiety",
      "count": 54
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 53
    },
    {
      "term": "Heart murmur",
      "count": 53
    },
    {
      "term": "Hypotension",
      "count": 53
    },
    {
      "term": "Leucocytosis NOS",
      "count": 50
    },
    {
      "term": "Limb weakness",
      "count": 49
    },
    {
      "term": "Hyperglycaemia",
      "count": 48
    },
    {
      "term": "Tremor",
      "count": 48
    },
    {
      "term": "Dehydration",
      "count": 46
    },
    {
      "term": "Proteinuria",
      "count": 46
    },
    {
      "term": "Renal failure",
      "count": 46
    },
    {
      "term": "Anaemia NOS",
      "count": 45
    },
    {
      "term": "Elevated liver enzymes",
      "count": 45
    },
    {
      "term": "Pale mucous membrane",
      "count": 45
    },
    {
      "term": "Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders')",
      "count": 43
    },
    {
      "term": "INEFFECTIVE, OTHER DRUG(S)",
      "count": 43
    },
    {
      "term": "Neutrophilia",
      "count": 43
    },
    {
      "term": "Not drinking",
      "count": 43
    },
    {
      "term": "Twitching",
      "count": 42
    },
    {
      "term": "Hypertension",
      "count": 41
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 40
    },
    {
      "term": "Gagging",
      "count": 40
    },
    {
      "term": "Abnormal breathing",
      "count": 38
    },
    {
      "term": "Fever",
      "count": 38
    },
    {
      "term": "Walking difficulty",
      "count": 38
    },
    {
      "term": "Appetite loss",
      "count": 37
    },
    {
      "term": "Collapse (see also 'Cardio-vascular' and 'Systemic disorders')",
      "count": 37
    },
    {
      "term": "Hyperactivity",
      "count": 37
    },
    {
      "term": "Drinking a lot",
      "count": 36
    },
    {
      "term": "Lack of efficacy (ectoparasite) - flea",
      "count": 36
    },
    {
      "term": "Monocytosis",
      "count": 36
    },
    {
      "term": "Decreased urine concentration",
      "count": 35
    },
    {
      "term": "Disorientation",
      "count": 35
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 35
    },
    {
      "term": "Low sodium-potassium ratio (Na:K ratio)",
      "count": 35
    },
    {
      "term": "Pulmonary oedema",
      "count": 35
    },
    {
      "term": "Distension of abdomen",
      "count": 34
    },
    {
      "term": "Sleepiness - systemic disorder",
      "count": 34
    },
    {
      "term": "Confusion",
      "count": 33
    },
    {
      "term": "Elevated total bilirubin",
      "count": 33
    },
    {
      "term": "Pancreatitis",
      "count": 33
    }
  ]
}