{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Diarrhoea",
      "count": 19
    },
    {
      "term": "Vomiting",
      "count": 17
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 15
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 15
    },
    {
      "term": "Accidental exposure",
      "count": 14
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 14
    },
    {
      "term": "Death by euthanasia",
      "count": 13
    },
    {
      "term": "No sign",
      "count": 13
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 13
    },
    {
      "term": "Anorexia",
      "count": 12
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 10
    },
    {
      "term": "Abnormal cytology",
      "count": 9
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 9
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 9
    },
    {
      "term": "Leucocytosis NOS",
      "count": 9
    },
    {
      "term": "Neutrophilia",
      "count": 9
    },
    {
      "term": "Weight loss",
      "count": 9
    },
    {
      "term": "Death",
      "count": 8
    },
    {
      "term": "Decreased appetite",
      "count": 8
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 8
    },
    {
      "term": "Pain NOS",
      "count": 8
    },
    {
      "term": "Skin lesion NOS",
      "count": 8
    },
    {
      "term": "Abdominal discomfort",
      "count": 7
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 7
    },
    {
      "term": "Ataxia",
      "count": 7
    },
    {
      "term": "Depression",
      "count": 7
    },
    {
      "term": "Bacterial skin infection NOS",
      "count": 6
    },
    {
      "term": "Enlarged lymph node (localised)",
      "count": 6
    },
    {
      "term": "Hypersalivation",
      "count": 6
    },
    {
      "term": "Inappetence",
      "count": 6
    },
    {
      "term": "Lack of efficacy (bacteria) - NOS",
      "count": 6
    },
    {
      "term": "Pruritus",
      "count": 6
    },
    {
      "term": "Distension of abdomen",
      "count": 5
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 5
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 5
    },
    {
      "term": "Elevated total bilirubin",
      "count": 5
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 5
    },
    {
      "term": "Fungal skin infection NOS",
      "count": 5
    },
    {
      "term": "Not eating",
      "count": 5
    },
    {
      "term": "Polydipsia",
      "count": 5
    },
    {
      "term": "Skin disorders NOS",
      "count": 5
    },
    {
      "term": "Walking difficulty",
      "count": 5
    },
    {
      "term": "Weakness",
      "count": 5
    },
    {
      "term": "Crust",
      "count": 4
    },
    {
      "term": "Dehydration",
      "count": 4
    },
    {
      "term": "Elevated amylase",
      "count": 4
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 4
    },
    {
      "term": "Emesis",
      "count": 4
    },
    {
      "term": "Eosinopenia",
      "count": 4
    },
    {
      "term": "Hyperphosphataemia",
      "count": 4
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 4
    },
    {
      "term": "Injection site swelling",
      "count": 4
    },
    {
      "term": "Loss of condition",
      "count": 4
    },
    {
      "term": "Malaise",
      "count": 4
    },
    {
      "term": "Monocytosis",
      "count": 4
    },
    {
      "term": "Panting",
      "count": 4
    },
    {
      "term": "Pyoderma",
      "count": 4
    },
    {
      "term": "Skin and tissue infection NOS",
      "count": 4
    },
    {
      "term": "Trembling",
      "count": 4
    },
    {
      "term": "Abdominal pain",
      "count": 3
    },
    {
      "term": "Anaemia NOS",
      "count": 3
    },
    {
      "term": "Ascites",
      "count": 3
    },
    {
      "term": "Breathing difficulty",
      "count": 3
    },
    {
      "term": "Bronchitis",
      "count": 3
    },
    {
      "term": "Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders')",
      "count": 3
    },
    {
      "term": "Convulsion",
      "count": 3
    },
    {
      "term": "Crackles on auscultation",
      "count": 3
    },
    {
      "term": "Cyanotic mucous membranes",
      "count": 3
    },
    {
      "term": "Decreased cholesterol (total)",
      "count": 3
    },
    {
      "term": "Difficulty eating NOS",
      "count": 3
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 3
    },
    {
      "term": "Eosinophilia",
      "count": 3
    },
    {
      "term": "General pain (see other SOCs for specific pain)",
      "count": 3
    },
    {
      "term": "Heavy breathing",
      "count": 3
    },
    {
      "term": "Hyperglycaemia",
      "count": 3
    },
    {
      "term": "Hyperpigmentation",
      "count": 3
    },
    {
      "term": "Limping",
      "count": 3
    },
    {
      "term": "Loose stool",
      "count": 3
    },
    {
      "term": "Lymphopenia",
      "count": 3
    },
    {
      "term": "Pancreas disorder",
      "count": 3
    },
    {
      "term": "Partial lack of efficacy",
      "count": 3
    },
    {
      "term": "Polyuria",
      "count": 3
    },
    {
      "term": "Proprioception deficit",
      "count": 3
    },
    {
      "term": "Proteinuria",
      "count": 3
    },
    {
      "term": "Reluctant to move",
      "count": 3
    },
    {
      "term": "Respiratory distress",
      "count": 3
    },
    {
      "term": "Seizure NOS",
      "count": 3
    },
    {
      "term": "Skin scab",
      "count": 3
    },
    {
      "term": "Skin slough",
      "count": 3
    },
    {
      "term": "Stertor",
      "count": 3
    },
    {
      "term": "Stomach pain",
      "count": 3
    },
    {
      "term": "Straining to defecate",
      "count": 3
    },
    {
      "term": "Swallowing difficult",
      "count": 3
    },
    {
      "term": "Swollen tongue",
      "count": 3
    },
    {
      "term": "Tongue disorder NOS",
      "count": 3
    },
    {
      "term": "Unable to walk",
      "count": 3
    },
    {
      "term": "Warm feeling to the touch",
      "count": 3
    },
    {
      "term": "Alopecia NOS",
      "count": 2
    },
    {
      "term": "Anxiety",
      "count": 2
    },
    {
      "term": "Application site bleeding",
      "count": 2
    }
  ]
}