{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Loss of hearing",
      "count": 553
    },
    {
      "term": "Deafness",
      "count": 298
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 248
    },
    {
      "term": "Hearing affected",
      "count": 158
    },
    {
      "term": "Vomiting",
      "count": 123
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 105
    },
    {
      "term": "Impaired hearing",
      "count": 103
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 101
    },
    {
      "term": "Hearing decreased",
      "count": 92
    },
    {
      "term": "Diarrhoea",
      "count": 90
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 77
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 65
    },
    {
      "term": "Partial deafness",
      "count": 65
    },
    {
      "term": "Ear infection NOS",
      "count": 62
    },
    {
      "term": "Ear discharge",
      "count": 61
    },
    {
      "term": "Pruritus",
      "count": 50
    },
    {
      "term": "Emesis",
      "count": 49
    },
    {
      "term": "Head shake - ear disorder",
      "count": 46
    },
    {
      "term": "Not eating",
      "count": 45
    },
    {
      "term": "Death by euthanasia",
      "count": 44
    },
    {
      "term": "Anorexia",
      "count": 43
    },
    {
      "term": "Seizure NOS",
      "count": 41
    },
    {
      "term": "Otitis externa",
      "count": 40
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 39
    },
    {
      "term": "Panting",
      "count": 38
    },
    {
      "term": "Abnormal cytology",
      "count": 37
    },
    {
      "term": "Other ear disorder NOS",
      "count": 37
    },
    {
      "term": "Vocalisation",
      "count": 37
    },
    {
      "term": "Shaking",
      "count": 36
    },
    {
      "term": "Decreased appetite",
      "count": 35
    },
    {
      "term": "Lack of efficacy (bacteria) - NOS",
      "count": 34
    },
    {
      "term": "Drug administration duration too long",
      "count": 33
    },
    {
      "term": "Skin lesion NOS",
      "count": 33
    },
    {
      "term": "Application site erythema",
      "count": 32
    },
    {
      "term": "Ataxia",
      "count": 32
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 32
    },
    {
      "term": "Weight loss",
      "count": 32
    },
    {
      "term": "Deafness NOS",
      "count": 31
    },
    {
      "term": "Pinnal erythema",
      "count": 31
    },
    {
      "term": "Accidental exposure",
      "count": 30
    },
    {
      "term": "Ear canal inflammation",
      "count": 29
    },
    {
      "term": "Ear pain",
      "count": 29
    },
    {
      "term": "Anxiety",
      "count": 28
    },
    {
      "term": "Head tilt - ear disorder",
      "count": 28
    },
    {
      "term": "Application site inflammation",
      "count": 27
    },
    {
      "term": "Inappetence",
      "count": 27
    },
    {
      "term": "Application site reddening",
      "count": 26
    },
    {
      "term": "Overdose",
      "count": 26
    },
    {
      "term": "Reddening of the skin",
      "count": 26
    },
    {
      "term": "Loose stool",
      "count": 25
    },
    {
      "term": "Application site pain",
      "count": 24
    },
    {
      "term": "Polydipsia",
      "count": 24
    },
    {
      "term": "Polyuria",
      "count": 24
    },
    {
      "term": "Bacterial skin infection NOS",
      "count": 23
    },
    {
      "term": "Depression",
      "count": 22
    },
    {
      "term": "Ear canal erythema",
      "count": 22
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 22
    },
    {
      "term": "Pain NOS",
      "count": 21
    },
    {
      "term": "Skin disorders NOS",
      "count": 21
    },
    {
      "term": "Bloody diarrhoea",
      "count": 20
    },
    {
      "term": "INEFFECTIVE, ATOPY CONTROL",
      "count": 20
    },
    {
      "term": "Ocular discharge",
      "count": 20
    },
    {
      "term": "Underdose",
      "count": 20
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 19
    },
    {
      "term": "Leucocytosis NOS",
      "count": 19
    },
    {
      "term": "Death",
      "count": 18
    },
    {
      "term": "Disorientation",
      "count": 18
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 18
    },
    {
      "term": "Scratching",
      "count": 18
    },
    {
      "term": "Anaemia NOS",
      "count": 17
    },
    {
      "term": "Itching",
      "count": 17
    },
    {
      "term": "Pinnal reddening",
      "count": 17
    },
    {
      "term": "Internal ear disorder",
      "count": 16
    },
    {
      "term": "Neutropenia",
      "count": 16
    },
    {
      "term": "Otitis NOS",
      "count": 16
    },
    {
      "term": "Crust",
      "count": 15
    },
    {
      "term": "Dermatitis",
      "count": 15
    },
    {
      "term": "Drooling",
      "count": 15
    },
    {
      "term": "Eye redness",
      "count": 15
    },
    {
      "term": "Licking",
      "count": 15
    },
    {
      "term": "Neutrophilia",
      "count": 15
    },
    {
      "term": "Reluctant to move",
      "count": 15
    },
    {
      "term": "Sneezing",
      "count": 15
    },
    {
      "term": "Temporary deafness",
      "count": 15
    },
    {
      "term": "Aggression",
      "count": 14
    },
    {
      "term": "Lack of efficacy (fungi) - NOS",
      "count": 14
    },
    {
      "term": "Monocytosis",
      "count": 14
    },
    {
      "term": "Not drinking",
      "count": 14
    },
    {
      "term": "Not himself/herself",
      "count": 14
    },
    {
      "term": "Otorrhoea",
      "count": 14
    },
    {
      "term": "Weakness",
      "count": 14
    },
    {
      "term": "Cough",
      "count": 13
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 13
    },
    {
      "term": "Flaking skin",
      "count": 13
    },
    {
      "term": "Fungal skin infection NOS",
      "count": 13
    },
    {
      "term": "Pyoderma",
      "count": 13
    },
    {
      "term": "Urinary incontinence",
      "count": 13
    },
    {
      "term": "Dehydration",
      "count": 12
    },
    {
      "term": "Ear canal disorder",
      "count": 12
    },
    {
      "term": "Ear irritation",
      "count": 12
    }
  ]
}