{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Lack of efficacy - NOS",
      "count": 20
    },
    {
      "term": "Vomiting",
      "count": 17
    },
    {
      "term": "Hypersalivation",
      "count": 11
    },
    {
      "term": "Ataxia",
      "count": 9
    },
    {
      "term": "Death",
      "count": 9
    },
    {
      "term": "Diarrhoea",
      "count": 9
    },
    {
      "term": "Fever",
      "count": 9
    },
    {
      "term": "Lack of efficacy (bacteria) - NOS",
      "count": 8
    },
    {
      "term": "Anorexia",
      "count": 7
    },
    {
      "term": "Death by euthanasia",
      "count": 7
    },
    {
      "term": "Lack of efficacy (fungi) - NOS",
      "count": 7
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 7
    },
    {
      "term": "Not eating",
      "count": 7
    },
    {
      "term": "Weight loss",
      "count": 6
    },
    {
      "term": "Decreased appetite",
      "count": 5
    },
    {
      "term": "Depression",
      "count": 5
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 5
    },
    {
      "term": "Horner's syndrome",
      "count": 5
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 5
    },
    {
      "term": "Pruritus",
      "count": 5
    },
    {
      "term": "Vocalisation",
      "count": 5
    },
    {
      "term": "Accidental exposure",
      "count": 4
    },
    {
      "term": "Application site erythema",
      "count": 4
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 4
    },
    {
      "term": "Dehydration",
      "count": 4
    },
    {
      "term": "Dermatitis",
      "count": 4
    },
    {
      "term": "Ear pain",
      "count": 4
    },
    {
      "term": "Abnormal cytology",
      "count": 3
    },
    {
      "term": "Anaemia NOS",
      "count": 3
    },
    {
      "term": "Application site skin change NOS",
      "count": 3
    },
    {
      "term": "Decreased drinking",
      "count": 3
    },
    {
      "term": "Ear pruritus",
      "count": 3
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 3
    },
    {
      "term": "Elevated liver enzymes",
      "count": 3
    },
    {
      "term": "Elevated total bilirubin",
      "count": 3
    },
    {
      "term": "Hiding",
      "count": 3
    },
    {
      "term": "Hyperglycaemia",
      "count": 3
    },
    {
      "term": "Hypoglycaemia",
      "count": 3
    },
    {
      "term": "Hypothermia",
      "count": 3
    },
    {
      "term": "Inappetence",
      "count": 3
    },
    {
      "term": "Lack of efficacy (ectoparasite) - Demodex",
      "count": 3
    },
    {
      "term": "Localised hair loss",
      "count": 3
    },
    {
      "term": "Loss of hearing",
      "count": 3
    },
    {
      "term": "Nasal discharge",
      "count": 3
    },
    {
      "term": "Neurological signs NOS",
      "count": 3
    },
    {
      "term": "Neutropenia",
      "count": 3
    },
    {
      "term": "Not drinking",
      "count": 3
    },
    {
      "term": "Otitis NOS",
      "count": 3
    },
    {
      "term": "Skin scab",
      "count": 3
    },
    {
      "term": "Tachycardia",
      "count": 3
    },
    {
      "term": "Urinary bladder disorder NOS",
      "count": 3
    },
    {
      "term": "Vestibular disorder NOS",
      "count": 3
    },
    {
      "term": "Abnormal menace reflex test",
      "count": 2
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 2
    },
    {
      "term": "Administration error NOS",
      "count": 2
    },
    {
      "term": "Alopecia",
      "count": 2
    },
    {
      "term": "Application site alopecia",
      "count": 2
    },
    {
      "term": "Application site bleeding",
      "count": 2
    },
    {
      "term": "Application site crust",
      "count": 2
    },
    {
      "term": "Application site dermatitis",
      "count": 2
    },
    {
      "term": "Application site pain",
      "count": 2
    },
    {
      "term": "Balance problem",
      "count": 2
    },
    {
      "term": "Blood in vomit",
      "count": 2
    },
    {
      "term": "Bloody diarrhoea",
      "count": 2
    },
    {
      "term": "Constipation",
      "count": 2
    },
    {
      "term": "Cough",
      "count": 2
    },
    {
      "term": "Crust",
      "count": 2
    },
    {
      "term": "Crying",
      "count": 2
    },
    {
      "term": "Crystalluria",
      "count": 2
    },
    {
      "term": "Decreased urine concentration",
      "count": 2
    },
    {
      "term": "Ear infection NOS",
      "count": 2
    },
    {
      "term": "Elevated creatinine",
      "count": 2
    },
    {
      "term": "Emesis (multiple)",
      "count": 2
    },
    {
      "term": "Excessive chewing, licking and/or grooming",
      "count": 2
    },
    {
      "term": "Eye disorder NOS (for photophobia see 'neurological')",
      "count": 2
    },
    {
      "term": "Head shake - ear disorder",
      "count": 2
    },
    {
      "term": "Head tilt - ear disorder",
      "count": 2
    },
    {
      "term": "Hearing affected",
      "count": 2
    },
    {
      "term": "Hyperactivity",
      "count": 2
    },
    {
      "term": "Hyperphosphataemia",
      "count": 2
    },
    {
      "term": "Hypokalaemia",
      "count": 2
    },
    {
      "term": "INEFFECTIVE, OTHER DRUG(S)",
      "count": 2
    },
    {
      "term": "Increased respiratory rate",
      "count": 2
    },
    {
      "term": "Lack of efficacy (bacteria) - Pasteurella multocida",
      "count": 2
    },
    {
      "term": "Malaise",
      "count": 2
    },
    {
      "term": "Musculoskeletal disorder NOS",
      "count": 2
    },
    {
      "term": "Non-regenerative anaemia",
      "count": 2
    },
    {
      "term": "Ocular discharge",
      "count": 2
    },
    {
      "term": "PR-LIVER, LESION(S)",
      "count": 2
    },
    {
      "term": "PR-SMALL INTESTINE, LESION(S)",
      "count": 2
    },
    {
      "term": "PR-STOMACH, LESION(S)",
      "count": 2
    },
    {
      "term": "Pale mucous membrane",
      "count": 2
    },
    {
      "term": "Scratching",
      "count": 2
    },
    {
      "term": "Shaking",
      "count": 2
    },
    {
      "term": "Skin hyperaemia",
      "count": 2
    },
    {
      "term": "Sneezing",
      "count": 2
    },
    {
      "term": "Staggering",
      "count": 2
    },
    {
      "term": "Tachypnoea",
      "count": 2
    },
    {
      "term": "Third eyelid protrusion",
      "count": 2
    },
    {
      "term": "Unclassifiable adverse event",
      "count": 2
    }
  ]
}