{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Diarrhoea",
      "count": 859
    },
    {
      "term": "Vomiting",
      "count": 835
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 502
    },
    {
      "term": "Anorexia",
      "count": 374
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 364
    },
    {
      "term": "Death by euthanasia",
      "count": 341
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 339
    },
    {
      "term": "Bloody diarrhoea",
      "count": 278
    },
    {
      "term": "Not eating",
      "count": 273
    },
    {
      "term": "Weight loss",
      "count": 254
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 248
    },
    {
      "term": "Death",
      "count": 235
    },
    {
      "term": "Emesis",
      "count": 235
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 218
    },
    {
      "term": "Decreased appetite",
      "count": 214
    },
    {
      "term": "Leucocytosis NOS",
      "count": 198
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 189
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 173
    },
    {
      "term": "Elevated total bilirubin",
      "count": 173
    },
    {
      "term": "Anaemia NOS",
      "count": 165
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 162
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 159
    },
    {
      "term": "Neutrophilia",
      "count": 159
    },
    {
      "term": "Dehydration",
      "count": 154
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 154
    },
    {
      "term": "Loose stool",
      "count": 152
    },
    {
      "term": "Fever",
      "count": 144
    },
    {
      "term": "Seizure NOS",
      "count": 144
    },
    {
      "term": "Elevated liver enzymes",
      "count": 137
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 133
    },
    {
      "term": "Ataxia",
      "count": 129
    },
    {
      "term": "Panting",
      "count": 121
    },
    {
      "term": "Thrombocytopenia",
      "count": 120
    },
    {
      "term": "Emesis (multiple)",
      "count": 117
    },
    {
      "term": "Elevated creatinine",
      "count": 116
    },
    {
      "term": "Pale mucous membrane",
      "count": 100
    },
    {
      "term": "Hypoproteinaemia",
      "count": 99
    },
    {
      "term": "Weakness",
      "count": 95
    },
    {
      "term": "Hyperphosphataemia",
      "count": 94
    },
    {
      "term": "Polydipsia",
      "count": 93
    },
    {
      "term": "Shaking",
      "count": 92
    },
    {
      "term": "Lymphopenia",
      "count": 91
    },
    {
      "term": "Inappetence",
      "count": 89
    },
    {
      "term": "Monocytosis",
      "count": 84
    },
    {
      "term": "Polyuria",
      "count": 83
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 82
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 82
    },
    {
      "term": "Icterus",
      "count": 74
    },
    {
      "term": "Abdominal pain",
      "count": 73
    },
    {
      "term": "Leucopenia NOS",
      "count": 72
    },
    {
      "term": "Neutropenia",
      "count": 68
    },
    {
      "term": "Proteinuria",
      "count": 68
    },
    {
      "term": "Lack of efficacy (endoparasite) - hookworm",
      "count": 67
    },
    {
      "term": "Hypoglycaemia",
      "count": 65
    },
    {
      "term": "Not drinking",
      "count": 64
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 63
    },
    {
      "term": "Pain NOS",
      "count": 63
    },
    {
      "term": "Pancreatitis",
      "count": 63
    },
    {
      "term": "Vocalisation",
      "count": 62
    },
    {
      "term": "Lateral recumbency",
      "count": 61
    },
    {
      "term": "Low platelet count",
      "count": 61
    },
    {
      "term": "Overdose",
      "count": 60
    },
    {
      "term": "Urinary tract infection",
      "count": 60
    },
    {
      "term": "Cough",
      "count": 58
    },
    {
      "term": "Blood in faeces",
      "count": 55
    },
    {
      "term": "Blood in vomit",
      "count": 55
    },
    {
      "term": "Tachycardia",
      "count": 55
    },
    {
      "term": "Tarry or black stool (see also haemorrhagic diarrhoea)",
      "count": 55
    },
    {
      "term": "Drooling",
      "count": 54
    },
    {
      "term": "Elevated amylase",
      "count": 53
    },
    {
      "term": "Facial swelling (see also 'Skin')",
      "count": 53
    },
    {
      "term": "Hyperglycaemia",
      "count": 52
    },
    {
      "term": "Nausea",
      "count": 52
    },
    {
      "term": "Unable to stand",
      "count": 52
    },
    {
      "term": "Pruritus",
      "count": 51
    },
    {
      "term": "Underdose",
      "count": 51
    },
    {
      "term": "Hypersalivation",
      "count": 49
    },
    {
      "term": "Urinary incontinence",
      "count": 49
    },
    {
      "term": "Restlessness",
      "count": 48
    },
    {
      "term": "Anxiety",
      "count": 47
    },
    {
      "term": "Limb weakness",
      "count": 47
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 46
    },
    {
      "term": "Hypokalaemia",
      "count": 46
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 45
    },
    {
      "term": "Hyponatremia",
      "count": 45
    },
    {
      "term": "Depression",
      "count": 44
    },
    {
      "term": "Dry mucous membrane",
      "count": 43
    },
    {
      "term": "Elevated lipase",
      "count": 43
    },
    {
      "term": "Hypochloraemia",
      "count": 43
    },
    {
      "term": "Mucous stool",
      "count": 43
    },
    {
      "term": "Urine abnormalities NOS",
      "count": 43
    },
    {
      "term": "Hypothermia",
      "count": 42
    },
    {
      "term": "Walking difficulty",
      "count": 42
    },
    {
      "term": "Adipsia",
      "count": 41
    },
    {
      "term": "Anaphylaxis",
      "count": 41
    },
    {
      "term": "Elevated renal parameters",
      "count": 41
    },
    {
      "term": "Gall bladder & bile duct disorder NOS",
      "count": 41
    },
    {
      "term": "Tense abdomen",
      "count": 41
    },
    {
      "term": "Decreased haematocrit",
      "count": 40
    },
    {
      "term": "Lameness",
      "count": 40
    }
  ]
}