{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 203
    },
    {
      "term": "Weight loss",
      "count": 144
    },
    {
      "term": "Anorexia",
      "count": 114
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 108
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 105
    },
    {
      "term": "Not eating",
      "count": 101
    },
    {
      "term": "Death by euthanasia",
      "count": 89
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 86
    },
    {
      "term": "Diarrhoea",
      "count": 78
    },
    {
      "term": "Decreased appetite",
      "count": 72
    },
    {
      "term": "Ataxia",
      "count": 71
    },
    {
      "term": "Death",
      "count": 68
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 67
    },
    {
      "term": "Vocalisation",
      "count": 64
    },
    {
      "term": "Dehydration",
      "count": 63
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 53
    },
    {
      "term": "Pruritus",
      "count": 52
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 50
    },
    {
      "term": "Hiding",
      "count": 48
    },
    {
      "term": "Seizure NOS",
      "count": 45
    },
    {
      "term": "Anaemia NOS",
      "count": 44
    },
    {
      "term": "Elevated creatinine",
      "count": 44
    },
    {
      "term": "Emesis",
      "count": 43
    },
    {
      "term": "Skin scab",
      "count": 43
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 42
    },
    {
      "term": "Ketosis",
      "count": 34
    },
    {
      "term": "Hyperglycaemia",
      "count": 33
    },
    {
      "term": "Not drinking",
      "count": 31
    },
    {
      "term": "Hyperthyroidism",
      "count": 29
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 28
    },
    {
      "term": "Dilated pupils",
      "count": 28
    },
    {
      "term": "Emesis (multiple)",
      "count": 28
    },
    {
      "term": "Inappetence",
      "count": 27
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 25
    },
    {
      "term": "Depression",
      "count": 24
    },
    {
      "term": "Elevated thyroxine (T4)",
      "count": 23
    },
    {
      "term": "Fever",
      "count": 23
    },
    {
      "term": "Localised hair loss",
      "count": 22
    },
    {
      "term": "Medication error NOS",
      "count": 22
    },
    {
      "term": "Inappropriate urination",
      "count": 21
    },
    {
      "term": "Constipation",
      "count": 20
    },
    {
      "term": "Decreased haematocrit",
      "count": 20
    },
    {
      "term": "Dermatitis",
      "count": 20
    },
    {
      "term": "Intentional misuse",
      "count": 20
    },
    {
      "term": "Itching",
      "count": 20
    },
    {
      "term": "Neutrophilia",
      "count": 20
    },
    {
      "term": "Partial lack of efficacy",
      "count": 20
    },
    {
      "term": "Scratching",
      "count": 20
    },
    {
      "term": "Hyperphosphataemia",
      "count": 19
    },
    {
      "term": "Hypokalaemia",
      "count": 19
    },
    {
      "term": "Pale mucous membrane",
      "count": 19
    },
    {
      "term": "Skin lesion NOS",
      "count": 19
    },
    {
      "term": "Tachycardia",
      "count": 19
    },
    {
      "term": "Adipsia",
      "count": 18
    },
    {
      "term": "Alopecia local",
      "count": 18
    },
    {
      "term": "Elevated renal parameters",
      "count": 18
    },
    {
      "term": "Leucocytosis NOS",
      "count": 18
    },
    {
      "term": "Polydipsia",
      "count": 18
    },
    {
      "term": "Agitation",
      "count": 17
    },
    {
      "term": "Hyperactivity",
      "count": 17
    },
    {
      "term": "Hypothermia",
      "count": 17
    },
    {
      "term": "Overdose",
      "count": 17
    },
    {
      "term": "Weakness",
      "count": 17
    },
    {
      "term": "Blindness",
      "count": 16
    },
    {
      "term": "Elevated total bilirubin",
      "count": 16
    },
    {
      "term": "Excoriation",
      "count": 16
    },
    {
      "term": "Panting",
      "count": 16
    },
    {
      "term": "Polyuria",
      "count": 16
    },
    {
      "term": "Urinary tract infection",
      "count": 16
    },
    {
      "term": "Drooling",
      "count": 15
    },
    {
      "term": "Facial pruritus",
      "count": 15
    },
    {
      "term": "Not himself/herself",
      "count": 15
    },
    {
      "term": "Reluctant to move",
      "count": 15
    },
    {
      "term": "Azotaemia",
      "count": 14
    },
    {
      "term": "Limb weakness",
      "count": 14
    },
    {
      "term": "Musculoskeletal disorder NOS",
      "count": 14
    },
    {
      "term": "Proteinuria",
      "count": 14
    },
    {
      "term": "Twitching",
      "count": 14
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 13
    },
    {
      "term": "Heart murmur",
      "count": 13
    },
    {
      "term": "Hypertension",
      "count": 13
    },
    {
      "term": "Hypotension",
      "count": 13
    },
    {
      "term": "Increased respiratory rate",
      "count": 13
    },
    {
      "term": "Lateral recumbency",
      "count": 13
    },
    {
      "term": "Lymphopenia",
      "count": 13
    },
    {
      "term": "Ocular discharge",
      "count": 13
    },
    {
      "term": "Open mouth breathing",
      "count": 13
    },
    {
      "term": "Restlessness",
      "count": 13
    },
    {
      "term": "Falling",
      "count": 12
    },
    {
      "term": "Hypoglycaemia",
      "count": 12
    },
    {
      "term": "Lack of efficacy (ectoparasite) - flea",
      "count": 12
    },
    {
      "term": "Neurological signs NOS",
      "count": 12
    },
    {
      "term": "Renal failure",
      "count": 12
    },
    {
      "term": "Tachypnoea",
      "count": 12
    },
    {
      "term": "Underdose",
      "count": 12
    },
    {
      "term": "Wobbliness",
      "count": 12
    },
    {
      "term": "Elevated liver enzymes",
      "count": 11
    },
    {
      "term": "Gait abnormality",
      "count": 11
    },
    {
      "term": "High pancreatic-specific lipase",
      "count": 11
    },
    {
      "term": "Hypersalivation",
      "count": 11
    }
  ]
}