{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Anorexia",
      "count": 1300
    },
    {
      "term": "Elevated creatinine",
      "count": 1253
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 1219
    },
    {
      "term": "Vomiting",
      "count": 1006
    },
    {
      "term": "Depression",
      "count": 896
    },
    {
      "term": "Renal failure",
      "count": 752
    },
    {
      "term": "Hyperphosphataemia",
      "count": 560
    },
    {
      "term": "Azotaemia",
      "count": 509
    },
    {
      "term": "Death by euthanasia",
      "count": 432
    },
    {
      "term": "Death",
      "count": 420
    },
    {
      "term": "Weight loss",
      "count": 325
    },
    {
      "term": "Dehydration",
      "count": 299
    },
    {
      "term": "Anaemia NOS",
      "count": 251
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 241
    },
    {
      "term": "Decreased urine concentration",
      "count": 234
    },
    {
      "term": "Diarrhoea",
      "count": 224
    },
    {
      "term": "Fever",
      "count": 181
    },
    {
      "term": "Polydipsia",
      "count": 159
    },
    {
      "term": "Hyperkalaemia",
      "count": 153
    },
    {
      "term": "Ataxia",
      "count": 151
    },
    {
      "term": "Hyperglycaemia",
      "count": 127
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 125
    },
    {
      "term": "Adipsia",
      "count": 124
    },
    {
      "term": "Not eating",
      "count": 124
    },
    {
      "term": "Elevated renal parameters",
      "count": 118
    },
    {
      "term": "Hiding",
      "count": 114
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 109
    },
    {
      "term": "Leucocytosis NOS",
      "count": 108
    },
    {
      "term": "Hypothermia",
      "count": 107
    },
    {
      "term": "Polyuria",
      "count": 105
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 104
    },
    {
      "term": "Vocalisation",
      "count": 100
    },
    {
      "term": "Haematuria",
      "count": 97
    },
    {
      "term": "Elevated total bilirubin",
      "count": 96
    },
    {
      "term": "Proteinuria",
      "count": 91
    },
    {
      "term": "Decreased appetite",
      "count": 90
    },
    {
      "term": "Accidental exposure",
      "count": 88
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 87
    },
    {
      "term": "Hyperproteinaemia",
      "count": 85
    },
    {
      "term": "Acute renal failure",
      "count": 79
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 78
    },
    {
      "term": "Hypersalivation",
      "count": 76
    },
    {
      "term": "Dyspnoea",
      "count": 70
    },
    {
      "term": "Labelled drug-drug interaction medication error",
      "count": 68
    },
    {
      "term": "Convulsion",
      "count": 66
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 66
    },
    {
      "term": "Constipation",
      "count": 63
    },
    {
      "term": "Labeled drug-species interaction",
      "count": 62
    },
    {
      "term": "PR-KIDNEY(S), LESION(S)",
      "count": 62
    },
    {
      "term": "Recumbency",
      "count": 62
    },
    {
      "term": "Renal disorder NOS",
      "count": 61
    },
    {
      "term": "Weakness",
      "count": 58
    },
    {
      "term": "Thrombocytopenia",
      "count": 57
    },
    {
      "term": "Elevated globulins",
      "count": 56
    },
    {
      "term": "Anuria",
      "count": 55
    },
    {
      "term": "Not drinking",
      "count": 55
    },
    {
      "term": "Pale mucous membrane",
      "count": 55
    },
    {
      "term": "Inappetence",
      "count": 54
    },
    {
      "term": "Dilated pupils",
      "count": 52
    },
    {
      "term": "Elevated amylase",
      "count": 52
    },
    {
      "term": "Hyperactivity",
      "count": 51
    },
    {
      "term": "Neutrophilia",
      "count": 51
    },
    {
      "term": "Icterus",
      "count": 50
    },
    {
      "term": "Skin lesion NOS",
      "count": 50
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 46
    },
    {
      "term": "Pain NOS",
      "count": 46
    },
    {
      "term": "Blindness",
      "count": 45
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 45
    },
    {
      "term": "Abdominal pain",
      "count": 44
    },
    {
      "term": "Urinary tract disorder NOS",
      "count": 44
    },
    {
      "term": "Hyponatremia",
      "count": 42
    },
    {
      "term": "Mydriasis",
      "count": 42
    },
    {
      "term": "Lymphopenia",
      "count": 41
    },
    {
      "term": "Reluctant to move",
      "count": 40
    },
    {
      "term": "Restlessness",
      "count": 39
    },
    {
      "term": "Stupor",
      "count": 39
    },
    {
      "term": "Blood in vomit",
      "count": 38
    },
    {
      "term": "Hypochloraemia",
      "count": 38
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 37
    },
    {
      "term": "Oral ulceration",
      "count": 37
    },
    {
      "term": "Cardiac arrest",
      "count": 36
    },
    {
      "term": "Leucopenia NOS",
      "count": 36
    },
    {
      "term": "Hypoproteinaemia",
      "count": 35
    },
    {
      "term": "Malaise",
      "count": 35
    },
    {
      "term": "Seizure NOS",
      "count": 33
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 32
    },
    {
      "term": "Pruritus",
      "count": 32
    },
    {
      "term": "Bloody diarrhoea",
      "count": 31
    },
    {
      "term": "Emesis",
      "count": 31
    },
    {
      "term": "Hypercalcaemia",
      "count": 31
    },
    {
      "term": "Urinary tract infection",
      "count": 31
    },
    {
      "term": "Elevated temperature",
      "count": 30
    },
    {
      "term": "Sneezing",
      "count": 30
    },
    {
      "term": "Twitching",
      "count": 30
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 29
    },
    {
      "term": "Hypoglycaemia",
      "count": 29
    },
    {
      "term": "PR-LIVER, LESION(S)",
      "count": 29
    },
    {
      "term": "Tachycardia",
      "count": 29
    },
    {
      "term": "Dysphoria",
      "count": 28
    },
    {
      "term": "Lung oedema",
      "count": 28
    }
  ]
}