{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 701
    },
    {
      "term": "Anorexia",
      "count": 525
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 444
    },
    {
      "term": "Death by euthanasia",
      "count": 441
    },
    {
      "term": "Not eating",
      "count": 405
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 365
    },
    {
      "term": "Weight loss",
      "count": 357
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 349
    },
    {
      "term": "Death",
      "count": 336
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 307
    },
    {
      "term": "Diarrhoea",
      "count": 297
    },
    {
      "term": "Ataxia",
      "count": 285
    },
    {
      "term": "Dehydration",
      "count": 280
    },
    {
      "term": "Hypersalivation",
      "count": 269
    },
    {
      "term": "Fever",
      "count": 254
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 240
    },
    {
      "term": "Decreased appetite",
      "count": 228
    },
    {
      "term": "Hyperglycaemia",
      "count": 226
    },
    {
      "term": "Hiding",
      "count": 210
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 191
    },
    {
      "term": "Anaemia NOS",
      "count": 181
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 180
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 172
    },
    {
      "term": "Elevated creatinine",
      "count": 164
    },
    {
      "term": "Hypothermia",
      "count": 162
    },
    {
      "term": "Vocalisation",
      "count": 160
    },
    {
      "term": "Dilated pupils",
      "count": 159
    },
    {
      "term": "Intentional misuse",
      "count": 155
    },
    {
      "term": "Drooling",
      "count": 151
    },
    {
      "term": "Not drinking",
      "count": 148
    },
    {
      "term": "Elevated total bilirubin",
      "count": 129
    },
    {
      "term": "Seizure NOS",
      "count": 125
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 121
    },
    {
      "term": "Leucocytosis NOS",
      "count": 120
    },
    {
      "term": "Inappetence",
      "count": 114
    },
    {
      "term": "Emesis (multiple)",
      "count": 113
    },
    {
      "term": "Hyperphosphataemia",
      "count": 111
    },
    {
      "term": "Hypokalaemia",
      "count": 104
    },
    {
      "term": "Lateral recumbency",
      "count": 104
    },
    {
      "term": "Neutrophilia",
      "count": 103
    },
    {
      "term": "Adipsia",
      "count": 100
    },
    {
      "term": "Bradycardia",
      "count": 100
    },
    {
      "term": "Tachypnoea",
      "count": 99
    },
    {
      "term": "INEFFECTIVE, ANTIEMETIC",
      "count": 95
    },
    {
      "term": "Pale mucous membrane",
      "count": 94
    },
    {
      "term": "Constipation",
      "count": 91
    },
    {
      "term": "Weakness",
      "count": 89
    },
    {
      "term": "Anaphylaxis",
      "count": 83
    },
    {
      "term": "Dyspnoea",
      "count": 83
    },
    {
      "term": "Depression",
      "count": 79
    },
    {
      "term": "Hypotension",
      "count": 78
    },
    {
      "term": "Nausea",
      "count": 76
    },
    {
      "term": "Panting",
      "count": 76
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 73
    },
    {
      "term": "Twitching",
      "count": 73
    },
    {
      "term": "Pain NOS",
      "count": 72
    },
    {
      "term": "Tachycardia",
      "count": 72
    },
    {
      "term": "Hyperactivity",
      "count": 71
    },
    {
      "term": "Ketosis",
      "count": 71
    },
    {
      "term": "Reluctant to move",
      "count": 70
    },
    {
      "term": "Elevated globulins",
      "count": 69
    },
    {
      "term": "Agitation",
      "count": 68
    },
    {
      "term": "Hypoglycaemia",
      "count": 68
    },
    {
      "term": "Not himself/herself",
      "count": 68
    },
    {
      "term": "Decreased haematocrit",
      "count": 67
    },
    {
      "term": "Proteinuria",
      "count": 67
    },
    {
      "term": "Sedation",
      "count": 67
    },
    {
      "term": "Dysphoria",
      "count": 66
    },
    {
      "term": "Heart murmur",
      "count": 66
    },
    {
      "term": "Neutropenia",
      "count": 66
    },
    {
      "term": "Emesis",
      "count": 65
    },
    {
      "term": "Open mouth breathing",
      "count": 65
    },
    {
      "term": "Falling",
      "count": 63
    },
    {
      "term": "Lymphopenia",
      "count": 63
    },
    {
      "term": "Not sleeping",
      "count": 61
    },
    {
      "term": "Unresponsive to stimuli",
      "count": 61
    },
    {
      "term": "Cardiac arrest",
      "count": 60
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 59
    },
    {
      "term": "Inappropriate urination",
      "count": 59
    },
    {
      "term": "Thrombocytopenia",
      "count": 58
    },
    {
      "term": "Azotaemia",
      "count": 57
    },
    {
      "term": "Injection site pain",
      "count": 57
    },
    {
      "term": "Medication error NOS",
      "count": 57
    },
    {
      "term": "Hyponatremia",
      "count": 56
    },
    {
      "term": "Abdominal pain",
      "count": 55
    },
    {
      "term": "Monocytosis",
      "count": 55
    },
    {
      "term": "Disorientation",
      "count": 54
    },
    {
      "term": "Elevated temperature",
      "count": 54
    },
    {
      "term": "Hypoproteinaemia",
      "count": 54
    },
    {
      "term": "Anisocoria",
      "count": 51
    },
    {
      "term": "Decreased packed cell volume (PCV)",
      "count": 51
    },
    {
      "term": "Renal failure",
      "count": 51
    },
    {
      "term": "Pleural effusion",
      "count": 49
    },
    {
      "term": "Hyperthermia",
      "count": 48
    },
    {
      "term": "Elevated renal parameters",
      "count": 47
    },
    {
      "term": "Leucopenia NOS",
      "count": 47
    },
    {
      "term": "Mydriasis",
      "count": 47
    },
    {
      "term": "Recumbency",
      "count": 47
    },
    {
      "term": "Walking difficulty",
      "count": 47
    },
    {
      "term": "Breathing difficulty",
      "count": 46
    }
  ]
}