{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 208
    },
    {
      "term": "Anorexia",
      "count": 166
    },
    {
      "term": "Lack of efficacy (bacteria) - NOS",
      "count": 140
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 101
    },
    {
      "term": "Depression",
      "count": 99
    },
    {
      "term": "Death by euthanasia",
      "count": 89
    },
    {
      "term": "Ataxia",
      "count": 77
    },
    {
      "term": "Death",
      "count": 74
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 74
    },
    {
      "term": "Diarrhoea",
      "count": 73
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 65
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 64
    },
    {
      "term": "Anaemia NOS",
      "count": 61
    },
    {
      "term": "Lameness",
      "count": 61
    },
    {
      "term": "Leucocytosis NOS",
      "count": 58
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 54
    },
    {
      "term": "Weight loss",
      "count": 50
    },
    {
      "term": "Polydipsia",
      "count": 49
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 46
    },
    {
      "term": "Convulsion",
      "count": 44
    },
    {
      "term": "Decreased appetite",
      "count": 44
    },
    {
      "term": "Elevated creatinine",
      "count": 42
    },
    {
      "term": "Fever",
      "count": 40
    },
    {
      "term": "Seizure NOS",
      "count": 37
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 36
    },
    {
      "term": "Cough",
      "count": 35
    },
    {
      "term": "Urinary tract infection",
      "count": 32
    },
    {
      "term": "Elevated total bilirubin",
      "count": 31
    },
    {
      "term": "Pain NOS",
      "count": 31
    },
    {
      "term": "Polyuria",
      "count": 31
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 30
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 29
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 29
    },
    {
      "term": "Reluctant to move",
      "count": 29
    },
    {
      "term": "Weakness",
      "count": 29
    },
    {
      "term": "Thrombocytopenia",
      "count": 28
    },
    {
      "term": "Trembling",
      "count": 28
    },
    {
      "term": "Blindness",
      "count": 27
    },
    {
      "term": "Not eating",
      "count": 27
    },
    {
      "term": "Neutrophilia",
      "count": 26
    },
    {
      "term": "Decreased urine concentration",
      "count": 24
    },
    {
      "term": "Facial oedema",
      "count": 24
    },
    {
      "term": "Pruritus",
      "count": 24
    },
    {
      "term": "Elevated liver enzymes",
      "count": 23
    },
    {
      "term": "Emesis",
      "count": 23
    },
    {
      "term": "Haematuria",
      "count": 22
    },
    {
      "term": "Hyperphosphataemia",
      "count": 22
    },
    {
      "term": "Head tilt - ear disorder",
      "count": 21
    },
    {
      "term": "Skin lesion NOS",
      "count": 21
    },
    {
      "term": "Urinary incontinence",
      "count": 21
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 20
    },
    {
      "term": "Proteinuria",
      "count": 20
    },
    {
      "term": "Restlessness",
      "count": 20
    },
    {
      "term": "Hypersalivation",
      "count": 18
    },
    {
      "term": "Inappetence",
      "count": 18
    },
    {
      "term": "INEFFECTIVE, ANTIBIOTIC",
      "count": 17
    },
    {
      "term": "Panting",
      "count": 17
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 16
    },
    {
      "term": "Limb weakness",
      "count": 16
    },
    {
      "term": "Abdominal pain",
      "count": 15
    },
    {
      "term": "Bloody diarrhoea",
      "count": 15
    },
    {
      "term": "CULTURE/TITER DATA ABNORMAL",
      "count": 15
    },
    {
      "term": "Hypoproteinaemia",
      "count": 15
    },
    {
      "term": "Joint pain",
      "count": 15
    },
    {
      "term": "Nystagmus",
      "count": 15
    },
    {
      "term": "Pale mucous membrane",
      "count": 15
    },
    {
      "term": "Underdose",
      "count": 15
    },
    {
      "term": "Dyspnoea",
      "count": 14
    },
    {
      "term": "Emesis (multiple)",
      "count": 14
    },
    {
      "term": "Leucopenia NOS",
      "count": 14
    },
    {
      "term": "Musculoskeletal disorder NOS",
      "count": 14
    },
    {
      "term": "Urine abnormalities NOS",
      "count": 14
    },
    {
      "term": "Vocalisation",
      "count": 14
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 13
    },
    {
      "term": "Hind limb paresis",
      "count": 13
    },
    {
      "term": "Icterus",
      "count": 13
    },
    {
      "term": "Loose stool",
      "count": 13
    },
    {
      "term": "Ocular discharge",
      "count": 13
    },
    {
      "term": "Urticaria",
      "count": 13
    },
    {
      "term": "Anxiety",
      "count": 12
    },
    {
      "term": "Disorientation",
      "count": 12
    },
    {
      "term": "Hyperglycaemia",
      "count": 12
    },
    {
      "term": "Hypoglycaemia",
      "count": 12
    },
    {
      "term": "Melaena",
      "count": 12
    },
    {
      "term": "Nausea",
      "count": 12
    },
    {
      "term": "Neurological signs NOS",
      "count": 12
    },
    {
      "term": "No sign",
      "count": 12
    },
    {
      "term": "Pyoderma",
      "count": 12
    },
    {
      "term": "Tachypnoea",
      "count": 12
    },
    {
      "term": "Vestibular disorder NOS",
      "count": 12
    },
    {
      "term": "Anaphylaxis",
      "count": 11
    },
    {
      "term": "Facial swelling (see also 'Skin')",
      "count": 11
    },
    {
      "term": "Hyperactivity",
      "count": 11
    },
    {
      "term": "Joint swelling",
      "count": 11
    },
    {
      "term": "Monocytosis",
      "count": 11
    },
    {
      "term": "Overdose",
      "count": 11
    },
    {
      "term": "Pneumonia",
      "count": 11
    },
    {
      "term": "Polypnoea",
      "count": 11
    },
    {
      "term": "Shaking",
      "count": 11
    },
    {
      "term": "Skin ulcer",
      "count": 11
    }
  ]
}