{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Behavioural disorder NOS",
      "count": 27
    },
    {
      "term": "Death",
      "count": 23
    },
    {
      "term": "Not eating",
      "count": 22
    },
    {
      "term": "Hyperthermia",
      "count": 17
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 17
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 15
    },
    {
      "term": "Anorexia",
      "count": 14
    },
    {
      "term": "Dilated pupils",
      "count": 14
    },
    {
      "term": "Dysphoria",
      "count": 14
    },
    {
      "term": "Agitation",
      "count": 13
    },
    {
      "term": "Weight loss",
      "count": 13
    },
    {
      "term": "Death by euthanasia",
      "count": 12
    },
    {
      "term": "Hyperactivity",
      "count": 11
    },
    {
      "term": "Ataxia",
      "count": 10
    },
    {
      "term": "Dehydration",
      "count": 10
    },
    {
      "term": "Not sleeping",
      "count": 10
    },
    {
      "term": "Vomiting",
      "count": 10
    },
    {
      "term": "Decreased appetite",
      "count": 9
    },
    {
      "term": "Hypothermia",
      "count": 9
    },
    {
      "term": "Hiding",
      "count": 8
    },
    {
      "term": "Hyperglycaemia",
      "count": 8
    },
    {
      "term": "Inappetence",
      "count": 8
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 8
    },
    {
      "term": "Not drinking",
      "count": 8
    },
    {
      "term": "Vocalisation",
      "count": 8
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 7
    },
    {
      "term": "Elevated creatinine",
      "count": 7
    },
    {
      "term": "Pacing",
      "count": 7
    },
    {
      "term": "Panting",
      "count": 7
    },
    {
      "term": "Aggression",
      "count": 6
    },
    {
      "term": "Decreased haematocrit",
      "count": 6
    },
    {
      "term": "Diarrhoea",
      "count": 6
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 6
    },
    {
      "term": "Elevated temperature",
      "count": 6
    },
    {
      "term": "Sedation",
      "count": 6
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 5
    },
    {
      "term": "Application site alopecia",
      "count": 5
    },
    {
      "term": "Cardiac arrest",
      "count": 5
    },
    {
      "term": "Constipation",
      "count": 5
    },
    {
      "term": "Falling",
      "count": 5
    },
    {
      "term": "Hypocalcaemia",
      "count": 5
    },
    {
      "term": "Hypokalaemia",
      "count": 5
    },
    {
      "term": "Hypoproteinaemia",
      "count": 5
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 5
    },
    {
      "term": "Restlessness",
      "count": 5
    },
    {
      "term": "Underdose",
      "count": 5
    },
    {
      "term": "Abdominal discomfort",
      "count": 4
    },
    {
      "term": "Abnormal breathing",
      "count": 4
    },
    {
      "term": "Anaemia NOS",
      "count": 4
    },
    {
      "term": "Arrhythmia",
      "count": 4
    },
    {
      "term": "Azotaemia",
      "count": 4
    },
    {
      "term": "Bradycardia",
      "count": 4
    },
    {
      "term": "Decreased packed cell volume (PCV)",
      "count": 4
    },
    {
      "term": "Dull",
      "count": 4
    },
    {
      "term": "Excitation",
      "count": 4
    },
    {
      "term": "Fever",
      "count": 4
    },
    {
      "term": "Hypotension",
      "count": 4
    },
    {
      "term": "Increased heart rate",
      "count": 4
    },
    {
      "term": "Low blood pressure",
      "count": 4
    },
    {
      "term": "Mydriasis",
      "count": 4
    },
    {
      "term": "Neutrophilia",
      "count": 4
    },
    {
      "term": "Not urinating",
      "count": 4
    },
    {
      "term": "Oral cavity disorder NOS",
      "count": 4
    },
    {
      "term": "Recovery prolonged",
      "count": 4
    },
    {
      "term": "Rolling",
      "count": 4
    },
    {
      "term": "Tachycardia",
      "count": 4
    },
    {
      "term": "Tachypnoea",
      "count": 4
    },
    {
      "term": "Unresponsive to stimuli",
      "count": 4
    },
    {
      "term": "Wobbliness",
      "count": 4
    },
    {
      "term": "Abdominal pain",
      "count": 3
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 3
    },
    {
      "term": "Adipsia",
      "count": 3
    },
    {
      "term": "Application site hair loss",
      "count": 3
    },
    {
      "term": "Application site scratching",
      "count": 3
    },
    {
      "term": "Blood in urine",
      "count": 3
    },
    {
      "term": "Cellulitis",
      "count": 3
    },
    {
      "term": "Decreased body temperature",
      "count": 3
    },
    {
      "term": "Decreased bowel movements",
      "count": 3
    },
    {
      "term": "Disorientation",
      "count": 3
    },
    {
      "term": "Drooling",
      "count": 3
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 3
    },
    {
      "term": "Elevated globulins",
      "count": 3
    },
    {
      "term": "Elevated total bilirubin",
      "count": 3
    },
    {
      "term": "Head shake - behavioural disorder",
      "count": 3
    },
    {
      "term": "Hyperexcitation",
      "count": 3
    },
    {
      "term": "Hypersalivation",
      "count": 3
    },
    {
      "term": "Hyponatremia",
      "count": 3
    },
    {
      "term": "Hypoxia",
      "count": 3
    },
    {
      "term": "Jaundice",
      "count": 3
    },
    {
      "term": "Lateral recumbency",
      "count": 3
    },
    {
      "term": "Local swelling (not application site)",
      "count": 3
    },
    {
      "term": "Low blood urea nitrogen (BUN)",
      "count": 3
    },
    {
      "term": "Low platelet count",
      "count": 3
    },
    {
      "term": "Lying down",
      "count": 3
    },
    {
      "term": "Medication error NOS",
      "count": 3
    },
    {
      "term": "Mouth pain",
      "count": 3
    },
    {
      "term": "Oedema NOS (see other SOCs for specific oedemas)",
      "count": 3
    },
    {
      "term": "Renal failure",
      "count": 3
    },
    {
      "term": "Respiratory distress",
      "count": 3
    },
    {
      "term": "Seizure NOS",
      "count": 3
    }
  ]
}