{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Death",
      "count": 853
    },
    {
      "term": "INEFFECTIVE, ANESTHESIA",
      "count": 565
    },
    {
      "term": "Cardiac arrest",
      "count": 292
    },
    {
      "term": "Apnoea",
      "count": 254
    },
    {
      "term": "Fever",
      "count": 251
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 239
    },
    {
      "term": "Recovery prolonged",
      "count": 239
    },
    {
      "term": "Ataxia",
      "count": 236
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 185
    },
    {
      "term": "Anorexia",
      "count": 184
    },
    {
      "term": "Not eating",
      "count": 175
    },
    {
      "term": "Hyperactivity",
      "count": 168
    },
    {
      "term": "Dilated pupils",
      "count": 161
    },
    {
      "term": "Hyperthermia",
      "count": 160
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 139
    },
    {
      "term": "Hypothermia",
      "count": 138
    },
    {
      "term": "Death by euthanasia",
      "count": 134
    },
    {
      "term": "Vomiting",
      "count": 115
    },
    {
      "term": "Dysphoria",
      "count": 114
    },
    {
      "term": "Cyanosis",
      "count": 108
    },
    {
      "term": "Elevated temperature",
      "count": 108
    },
    {
      "term": "Blindness",
      "count": 106
    },
    {
      "term": "Convulsion",
      "count": 106
    },
    {
      "term": "Seizure NOS",
      "count": 105
    },
    {
      "term": "Hypersalivation",
      "count": 104
    },
    {
      "term": "Bradycardia",
      "count": 96
    },
    {
      "term": "INEFFECTIVE, SEDATION",
      "count": 88
    },
    {
      "term": "Sedation prolonged",
      "count": 88
    },
    {
      "term": "Dehydration",
      "count": 82
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 81
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 81
    },
    {
      "term": "Hyperexcitation",
      "count": 80
    },
    {
      "term": "Vocalisation",
      "count": 78
    },
    {
      "term": "Weight loss",
      "count": 78
    },
    {
      "term": "Tachycardia",
      "count": 76
    },
    {
      "term": "Twitching",
      "count": 76
    },
    {
      "term": "Agitation",
      "count": 74
    },
    {
      "term": "Depression",
      "count": 72
    },
    {
      "term": "Mydriasis",
      "count": 72
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 67
    },
    {
      "term": "Dyspnoea",
      "count": 65
    },
    {
      "term": "Hiding",
      "count": 64
    },
    {
      "term": "Diarrhoea",
      "count": 62
    },
    {
      "term": "Not sleeping",
      "count": 62
    },
    {
      "term": "Restlessness",
      "count": 61
    },
    {
      "term": "Aggression",
      "count": 60
    },
    {
      "term": "Underdose",
      "count": 59
    },
    {
      "term": "Elevated creatinine",
      "count": 58
    },
    {
      "term": "Not drinking",
      "count": 58
    },
    {
      "term": "Panting",
      "count": 58
    },
    {
      "term": "Drooling",
      "count": 56
    },
    {
      "term": "Tachypnoea",
      "count": 55
    },
    {
      "term": "Hyperglycaemia",
      "count": 54
    },
    {
      "term": "Respiratory arrest",
      "count": 52
    },
    {
      "term": "Pale mucous membrane",
      "count": 51
    },
    {
      "term": "Sedation",
      "count": 51
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 50
    },
    {
      "term": "Decreased appetite",
      "count": 49
    },
    {
      "term": "Hyperphosphataemia",
      "count": 47
    },
    {
      "term": "Anaemia NOS",
      "count": 45
    },
    {
      "term": "Application site alopecia",
      "count": 43
    },
    {
      "term": "Intentional misuse",
      "count": 42
    },
    {
      "term": "Pain NOS",
      "count": 42
    },
    {
      "term": "Lateral recumbency",
      "count": 41
    },
    {
      "term": "Hypotension",
      "count": 40
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 39
    },
    {
      "term": "Head bobbing",
      "count": 39
    },
    {
      "term": "Anisocoria",
      "count": 38
    },
    {
      "term": "Application site hair loss",
      "count": 36
    },
    {
      "term": "Adipsia",
      "count": 34
    },
    {
      "term": "Neurological signs NOS",
      "count": 34
    },
    {
      "term": "Unresponsive to stimuli",
      "count": 34
    },
    {
      "term": "Inappetence",
      "count": 33
    },
    {
      "term": "Nystagmus",
      "count": 33
    },
    {
      "term": "Open mouth breathing",
      "count": 32
    },
    {
      "term": "Recumbency",
      "count": 32
    },
    {
      "term": "Weakness",
      "count": 32
    },
    {
      "term": "Hyperaesthesia",
      "count": 31
    },
    {
      "term": "Disorientation",
      "count": 30
    },
    {
      "term": "PR-HEART, LESION(S)",
      "count": 30
    },
    {
      "term": "Trembling",
      "count": 30
    },
    {
      "term": "Decreased body temperature",
      "count": 29
    },
    {
      "term": "Pacing",
      "count": 29
    },
    {
      "term": "Prolonged anaesthesia",
      "count": 29
    },
    {
      "term": "Respiratory distress",
      "count": 29
    },
    {
      "term": "Shaking",
      "count": 28
    },
    {
      "term": "Anxiety",
      "count": 27
    },
    {
      "term": "Falling",
      "count": 27
    },
    {
      "term": "Anaphylaxis",
      "count": 26
    },
    {
      "term": "Constipation",
      "count": 26
    },
    {
      "term": "Neutrophilia",
      "count": 25
    },
    {
      "term": "Pulmonary oedema",
      "count": 25
    },
    {
      "term": "Cardiorespiratory arrest",
      "count": 24
    },
    {
      "term": "Confusion",
      "count": 24
    },
    {
      "term": "Febrile",
      "count": 24
    },
    {
      "term": "Hyperproteinaemia",
      "count": 24
    },
    {
      "term": "Abnormal menace reflex test",
      "count": 23
    },
    {
      "term": "Low blood pressure",
      "count": 23
    },
    {
      "term": "Tongue ulceration",
      "count": 23
    },
    {
      "term": "Abnormal breathing",
      "count": 22
    }
  ]
}