{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Lack of efficacy - NOS",
      "count": 8
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 6
    },
    {
      "term": "Fever",
      "count": 5
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 5
    },
    {
      "term": "Cough",
      "count": 4
    },
    {
      "term": "Diarrhoea",
      "count": 4
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 4
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 4
    },
    {
      "term": "Polyuria",
      "count": 4
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 3
    },
    {
      "term": "Anxiety",
      "count": 3
    },
    {
      "term": "Death by euthanasia",
      "count": 3
    },
    {
      "term": "Decreased appetite",
      "count": 3
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 3
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 3
    },
    {
      "term": "Partial lack of efficacy",
      "count": 3
    },
    {
      "term": "Polydipsia",
      "count": 3
    },
    {
      "term": "Pruritus",
      "count": 3
    },
    {
      "term": "Seizure NOS",
      "count": 3
    },
    {
      "term": "Vomiting",
      "count": 3
    },
    {
      "term": "Abnormal cytology",
      "count": 2
    },
    {
      "term": "Anaemia NOS",
      "count": 2
    },
    {
      "term": "Anorexia",
      "count": 2
    },
    {
      "term": "Death",
      "count": 2
    },
    {
      "term": "Decreased activity",
      "count": 2
    },
    {
      "term": "Decreased haematocrit",
      "count": 2
    },
    {
      "term": "Dry eye",
      "count": 2
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 2
    },
    {
      "term": "Fungal skin infection NOS",
      "count": 2
    },
    {
      "term": "High sodium-potassium ratio (Na:K ratio)",
      "count": 2
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 2
    },
    {
      "term": "Hypokalaemia",
      "count": 2
    },
    {
      "term": "Hypoproteinaemia",
      "count": 2
    },
    {
      "term": "INEFFECTIVE, ATOPY CONTROL",
      "count": 2
    },
    {
      "term": "Inappetence",
      "count": 2
    },
    {
      "term": "Laboured breathing",
      "count": 2
    },
    {
      "term": "Lack of efficacy (endoparasite) - heartworm",
      "count": 2
    },
    {
      "term": "Leucopenia NOS",
      "count": 2
    },
    {
      "term": "Licking",
      "count": 2
    },
    {
      "term": "Liver disorder NOS",
      "count": 2
    },
    {
      "term": "Lymphocytosis",
      "count": 2
    },
    {
      "term": "Lymphopenia",
      "count": 2
    },
    {
      "term": "Malaise",
      "count": 2
    },
    {
      "term": "Pain NOS",
      "count": 2
    },
    {
      "term": "Pulmonary disorder NOS",
      "count": 2
    },
    {
      "term": "Reddening of the skin",
      "count": 2
    },
    {
      "term": "Ringworm",
      "count": 2
    },
    {
      "term": "Sneezing",
      "count": 2
    },
    {
      "term": "Weight loss",
      "count": 2
    },
    {
      "term": "Anisocoria",
      "count": 1
    },
    {
      "term": "Ataxia",
      "count": 1
    },
    {
      "term": "Balance impaired",
      "count": 1
    },
    {
      "term": "Barking",
      "count": 1
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 1
    },
    {
      "term": "Bloody diarrhoea",
      "count": 1
    },
    {
      "term": "Breathing difficulty",
      "count": 1
    },
    {
      "term": "Collapse NOS (see also Cardio-vascular and Neurological disorders)",
      "count": 1
    },
    {
      "term": "Cough, hacking",
      "count": 1
    },
    {
      "term": "Crying",
      "count": 1
    },
    {
      "term": "Cushings disease NOS",
      "count": 1
    },
    {
      "term": "Decreased drinking",
      "count": 1
    },
    {
      "term": "Dehydration",
      "count": 1
    },
    {
      "term": "Demodicosis",
      "count": 1
    },
    {
      "term": "Dermatitis",
      "count": 1
    },
    {
      "term": "Difficulty standing",
      "count": 1
    },
    {
      "term": "Dry mouth",
      "count": 1
    },
    {
      "term": "Dyspnoea",
      "count": 1
    },
    {
      "term": "Ear canal disorder",
      "count": 1
    },
    {
      "term": "Elevated creatinine",
      "count": 1
    },
    {
      "term": "Elevated globulins",
      "count": 1
    },
    {
      "term": "Elevated haematocrit",
      "count": 1
    },
    {
      "term": "Elevated liver enzymes",
      "count": 1
    },
    {
      "term": "Elevated mean corpuscular volume (MCV)",
      "count": 1
    },
    {
      "term": "Enlarged lymph node (localised)",
      "count": 1
    },
    {
      "term": "Enlarged lymph nodes (generalised)",
      "count": 1
    },
    {
      "term": "Excessive thirst",
      "count": 1
    },
    {
      "term": "Falling",
      "count": 1
    },
    {
      "term": "Febrile",
      "count": 1
    },
    {
      "term": "Foaming at the mouth",
      "count": 1
    },
    {
      "term": "Focal seizure",
      "count": 1
    },
    {
      "term": "Food refusal",
      "count": 1
    },
    {
      "term": "Generalised weakness",
      "count": 1
    },
    {
      "term": "Glossitis",
      "count": 1
    },
    {
      "term": "Hair loss NOS",
      "count": 1
    },
    {
      "term": "Harsh lung sounds",
      "count": 1
    },
    {
      "term": "Head shake - behavioural disorder",
      "count": 1
    },
    {
      "term": "Hiding",
      "count": 1
    },
    {
      "term": "Hyperphosphataemia",
      "count": 1
    },
    {
      "term": "Hypocalcaemia",
      "count": 1
    },
    {
      "term": "INEFFECTIVE, ANTIINFLAMMATORY",
      "count": 1
    },
    {
      "term": "Immune mediated haemolytic anaemia",
      "count": 1
    },
    {
      "term": "Immune mediated thrombocytopenia",
      "count": 1
    },
    {
      "term": "Inappropriate schedule of drug administration",
      "count": 1
    },
    {
      "term": "Inappropriate urination",
      "count": 1
    },
    {
      "term": "Increased band neutrophilia",
      "count": 1
    },
    {
      "term": "Involuntary urination",
      "count": 1
    },
    {
      "term": "Itching",
      "count": 1
    },
    {
      "term": "Lack of response to owner",
      "count": 1
    },
    {
      "term": "Lameness",
      "count": 1
    },
    {
      "term": "Leucocytosis NOS",
      "count": 1
    }
  ]
}