{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Death",
      "count": 279
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 218
    },
    {
      "term": "Not eating",
      "count": 185
    },
    {
      "term": "Dilated pupils",
      "count": 170
    },
    {
      "term": "Cardiac arrest",
      "count": 139
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 133
    },
    {
      "term": "Hyperactivity",
      "count": 128
    },
    {
      "term": "Fever",
      "count": 127
    },
    {
      "term": "Anorexia",
      "count": 125
    },
    {
      "term": "Ataxia",
      "count": 124
    },
    {
      "term": "Hyperthermia",
      "count": 124
    },
    {
      "term": "Dysphoria",
      "count": 121
    },
    {
      "term": "Hypothermia",
      "count": 107
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 101
    },
    {
      "term": "Elevated temperature",
      "count": 88
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 85
    },
    {
      "term": "Not sleeping",
      "count": 85
    },
    {
      "term": "Hiding",
      "count": 84
    },
    {
      "term": "Recovery prolonged",
      "count": 84
    },
    {
      "term": "Death by euthanasia",
      "count": 83
    },
    {
      "term": "Vomiting",
      "count": 82
    },
    {
      "term": "Agitation",
      "count": 79
    },
    {
      "term": "Apnoea",
      "count": 76
    },
    {
      "term": "Weight loss",
      "count": 76
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 71
    },
    {
      "term": "Not drinking",
      "count": 70
    },
    {
      "term": "Hypotension",
      "count": 67
    },
    {
      "term": "Bradycardia",
      "count": 66
    },
    {
      "term": "Vocalisation",
      "count": 62
    },
    {
      "term": "Tachycardia",
      "count": 60
    },
    {
      "term": "INEFFECTIVE, ANESTHESIA",
      "count": 59
    },
    {
      "term": "Blindness",
      "count": 58
    },
    {
      "term": "Dehydration",
      "count": 58
    },
    {
      "term": "Decreased appetite",
      "count": 55
    },
    {
      "term": "Hyperglycaemia",
      "count": 55
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 54
    },
    {
      "term": "Diarrhoea",
      "count": 50
    },
    {
      "term": "Elevated creatinine",
      "count": 50
    },
    {
      "term": "Seizure NOS",
      "count": 50
    },
    {
      "term": "Hypersalivation",
      "count": 49
    },
    {
      "term": "Restlessness",
      "count": 49
    },
    {
      "term": "Anaemia NOS",
      "count": 48
    },
    {
      "term": "Application site hair loss",
      "count": 47
    },
    {
      "term": "Twitching",
      "count": 47
    },
    {
      "term": "Respiratory arrest",
      "count": 46
    },
    {
      "term": "Panting",
      "count": 45
    },
    {
      "term": "Sedation",
      "count": 45
    },
    {
      "term": "Decreased body temperature",
      "count": 43
    },
    {
      "term": "Mydriasis",
      "count": 43
    },
    {
      "term": "Pale mucous membrane",
      "count": 43
    },
    {
      "term": "Cyanosis",
      "count": 41
    },
    {
      "term": "Application site alopecia",
      "count": 40
    },
    {
      "term": "Tachypnoea",
      "count": 40
    },
    {
      "term": "Drooling",
      "count": 39
    },
    {
      "term": "Inappetence",
      "count": 39
    },
    {
      "term": "Pacing",
      "count": 39
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 38
    },
    {
      "term": "Hyperphosphataemia",
      "count": 36
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 35
    },
    {
      "term": "Increased heart rate",
      "count": 33
    },
    {
      "term": "Sedation prolonged",
      "count": 33
    },
    {
      "term": "Aggression",
      "count": 31
    },
    {
      "term": "Falling",
      "count": 31
    },
    {
      "term": "Heart murmur",
      "count": 31
    },
    {
      "term": "Lateral recumbency",
      "count": 31
    },
    {
      "term": "Reluctant to move",
      "count": 29
    },
    {
      "term": "Disorientation",
      "count": 28
    },
    {
      "term": "Low blood pressure",
      "count": 28
    },
    {
      "term": "Neutrophilia",
      "count": 28
    },
    {
      "term": "Depression",
      "count": 27
    },
    {
      "term": "Pulmonary oedema",
      "count": 27
    },
    {
      "term": "Unresponsive to stimuli",
      "count": 27
    },
    {
      "term": "Not himself/herself",
      "count": 26
    },
    {
      "term": "Pain NOS",
      "count": 26
    },
    {
      "term": "Staring",
      "count": 24
    },
    {
      "term": "Wobbliness",
      "count": 24
    },
    {
      "term": "Adipsia",
      "count": 23
    },
    {
      "term": "Dyspnoea",
      "count": 23
    },
    {
      "term": "Elevated total bilirubin",
      "count": 23
    },
    {
      "term": "Quiet",
      "count": 23
    },
    {
      "term": "Third eyelid protrusion",
      "count": 23
    },
    {
      "term": "Increased respiratory rate",
      "count": 22
    },
    {
      "term": "Proteinuria",
      "count": 22
    },
    {
      "term": "Underdose",
      "count": 22
    },
    {
      "term": "Walking difficulty",
      "count": 22
    },
    {
      "term": "Anuria",
      "count": 21
    },
    {
      "term": "Intentional misuse",
      "count": 21
    },
    {
      "term": "Surgical site disorder",
      "count": 21
    },
    {
      "term": "Azotaemia",
      "count": 20
    },
    {
      "term": "Constipation",
      "count": 20
    },
    {
      "term": "Necropsy performed",
      "count": 20
    },
    {
      "term": "Unable to stand",
      "count": 20
    },
    {
      "term": "Abnormal menace reflex test",
      "count": 19
    },
    {
      "term": "Anisocoria",
      "count": 19
    },
    {
      "term": "Anxiety",
      "count": 19
    },
    {
      "term": "Excitation",
      "count": 19
    },
    {
      "term": "Inappropriate urination",
      "count": 19
    },
    {
      "term": "Nystagmus",
      "count": 19
    },
    {
      "term": "Cardiac disorder NOS",
      "count": 18
    },
    {
      "term": "Elevated globulins",
      "count": 18
    }
  ]
}