{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Lack of efficacy - NOS",
      "count": 321
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 230
    },
    {
      "term": "Diarrhoea",
      "count": 196
    },
    {
      "term": "Vomiting",
      "count": 169
    },
    {
      "term": "Neutropenia",
      "count": 168
    },
    {
      "term": "Decreased haematocrit",
      "count": 132
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 119
    },
    {
      "term": "Lymphopenia",
      "count": 113
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 99
    },
    {
      "term": "Leucopenia NOS",
      "count": 97
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 93
    },
    {
      "term": "Anaemia NOS",
      "count": 90
    },
    {
      "term": "Decreased red blood cell count",
      "count": 84
    },
    {
      "term": "Eosinopenia",
      "count": 80
    },
    {
      "term": "Leukopenia NOS",
      "count": 75
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 73
    },
    {
      "term": "Decreased haemoglobin",
      "count": 72
    },
    {
      "term": "Death by euthanasia",
      "count": 67
    },
    {
      "term": "Decreased appetite",
      "count": 58
    },
    {
      "term": "Itching",
      "count": 56
    },
    {
      "term": "Anorexia",
      "count": 54
    },
    {
      "term": "Weight loss",
      "count": 54
    },
    {
      "term": "Fever",
      "count": 52
    },
    {
      "term": "Pruritus",
      "count": 52
    },
    {
      "term": "Seizure NOS",
      "count": 51
    },
    {
      "term": "Polyuria",
      "count": 50
    },
    {
      "term": "Low platelet count",
      "count": 46
    },
    {
      "term": "Not eating",
      "count": 46
    },
    {
      "term": "Urinary tract infection",
      "count": 46
    },
    {
      "term": "Decreased percentage of reticulocytes",
      "count": 45
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 41
    },
    {
      "term": "Polydipsia",
      "count": 41
    },
    {
      "term": "Cough",
      "count": 40
    },
    {
      "term": "Proteinuria",
      "count": 39
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 38
    },
    {
      "term": "Monocytopenia",
      "count": 38
    },
    {
      "term": "Death",
      "count": 37
    },
    {
      "term": "Panting",
      "count": 37
    },
    {
      "term": "Thrombocytopenia",
      "count": 37
    },
    {
      "term": "Neutrophilia",
      "count": 36
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 34
    },
    {
      "term": "Emesis (multiple)",
      "count": 33
    },
    {
      "term": "Licking",
      "count": 33
    },
    {
      "term": "Underdose",
      "count": 33
    },
    {
      "term": "Elevated creatinine",
      "count": 30
    },
    {
      "term": "Haematuria",
      "count": 30
    },
    {
      "term": "Shaking",
      "count": 30
    },
    {
      "term": "Inappetence",
      "count": 29
    },
    {
      "term": "Hypoproteinaemia",
      "count": 28
    },
    {
      "term": "Monocytosis",
      "count": 28
    },
    {
      "term": "Weight gain",
      "count": 28
    },
    {
      "term": "Aggression",
      "count": 27
    },
    {
      "term": "Hyperglycaemia",
      "count": 27
    },
    {
      "term": "Leucocytosis NOS",
      "count": 27
    },
    {
      "term": "Pain NOS",
      "count": 27
    },
    {
      "term": "Skin disorders NOS",
      "count": 27
    },
    {
      "term": "Abnormal cytology",
      "count": 26
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 26
    },
    {
      "term": "Mass NOS",
      "count": 26
    },
    {
      "term": "Non-regenerative anaemia",
      "count": 26
    },
    {
      "term": "Anxiety",
      "count": 24
    },
    {
      "term": "Elevated cholesterol (total)",
      "count": 24
    },
    {
      "term": "Hives (see also Skin)",
      "count": 24
    },
    {
      "term": "Not himself/herself",
      "count": 24
    },
    {
      "term": "Ear infection NOS",
      "count": 23
    },
    {
      "term": "Elevated liver enzymes NOS",
      "count": 23
    },
    {
      "term": "Inappropriate urination",
      "count": 23
    },
    {
      "term": "Skin and tissue infection NOS",
      "count": 23
    },
    {
      "term": "Skin lesion NOS",
      "count": 23
    },
    {
      "term": "Urinary incontinence",
      "count": 23
    },
    {
      "term": "Dehydration",
      "count": 22
    },
    {
      "term": "Hypochloraemia",
      "count": 22
    },
    {
      "term": "Overdose",
      "count": 22
    },
    {
      "term": "Platelet disorder NOS",
      "count": 22
    },
    {
      "term": "Reddening of the skin",
      "count": 22
    },
    {
      "term": "Thrombocytosis",
      "count": 22
    },
    {
      "term": "Weakness",
      "count": 22
    },
    {
      "term": "Decreased packed cell volume (PCV)",
      "count": 21
    },
    {
      "term": "Elevated globulins",
      "count": 21
    },
    {
      "term": "Loose stool",
      "count": 21
    },
    {
      "term": "Urine abnormalities NOS",
      "count": 21
    },
    {
      "term": "Ataxia",
      "count": 20
    },
    {
      "term": "Bloody diarrhoea",
      "count": 20
    },
    {
      "term": "Increased percentage reticulocytes",
      "count": 20
    },
    {
      "term": "Pale mucous membrane",
      "count": 20
    },
    {
      "term": "Reduced globulins",
      "count": 20
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 19
    },
    {
      "term": "Pancreatitis NOS",
      "count": 19
    },
    {
      "term": "Blood in urine",
      "count": 18
    },
    {
      "term": "Elevated total bilirubin",
      "count": 18
    },
    {
      "term": "Hair loss NOS",
      "count": 18
    },
    {
      "term": "Low thyroxine (T4)",
      "count": 18
    },
    {
      "term": "Sleepiness - systemic disorder",
      "count": 18
    },
    {
      "term": "Bacterial skin infection NOS",
      "count": 17
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 17
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 17
    },
    {
      "term": "Breathing difficulty",
      "count": 16
    },
    {
      "term": "Lameness",
      "count": 16
    },
    {
      "term": "Papilloma",
      "count": 16
    },
    {
      "term": "Pyoderma",
      "count": 16
    }
  ]
}