{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 1425
    },
    {
      "term": "Diarrhoea",
      "count": 1256
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 958
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 659
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 508
    },
    {
      "term": "Death by euthanasia",
      "count": 476
    },
    {
      "term": "Not eating",
      "count": 466
    },
    {
      "term": "Decreased appetite",
      "count": 428
    },
    {
      "term": "Bloody diarrhoea",
      "count": 392
    },
    {
      "term": "Weight loss",
      "count": 347
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 340
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 317
    },
    {
      "term": "Elevated creatinine",
      "count": 301
    },
    {
      "term": "Anorexia",
      "count": 287
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 284
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 284
    },
    {
      "term": "Panting",
      "count": 282
    },
    {
      "term": "Seizure NOS",
      "count": 264
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 258
    },
    {
      "term": "Death",
      "count": 248
    },
    {
      "term": "Loose stool",
      "count": 237
    },
    {
      "term": "Elevated liver enzymes",
      "count": 215
    },
    {
      "term": "Ataxia",
      "count": 210
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 188
    },
    {
      "term": "Polydipsia",
      "count": 184
    },
    {
      "term": "Anaemia NOS",
      "count": 181
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 171
    },
    {
      "term": "Inappetence",
      "count": 170
    },
    {
      "term": "Polyuria",
      "count": 163
    },
    {
      "term": "INEFFECTIVE, ANTIINFLAMMATORY",
      "count": 140
    },
    {
      "term": "Pain NOS",
      "count": 140
    },
    {
      "term": "Limb weakness",
      "count": 139
    },
    {
      "term": "Weakness",
      "count": 136
    },
    {
      "term": "Dehydration",
      "count": 132
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 130
    },
    {
      "term": "Urinary tract infection",
      "count": 128
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 121
    },
    {
      "term": "Leucocytosis NOS",
      "count": 121
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 120
    },
    {
      "term": "Emesis (multiple)",
      "count": 119
    },
    {
      "term": "Proteinuria",
      "count": 116
    },
    {
      "term": "Neutrophilia",
      "count": 115
    },
    {
      "term": "Hyperphosphataemia",
      "count": 112
    },
    {
      "term": "Urinary incontinence",
      "count": 109
    },
    {
      "term": "Restlessness",
      "count": 106
    },
    {
      "term": "Blood in vomit",
      "count": 104
    },
    {
      "term": "Elevated renal parameters",
      "count": 102
    },
    {
      "term": "Inappropriate urination",
      "count": 102
    },
    {
      "term": "Overdose",
      "count": 99
    },
    {
      "term": "Tarry or black stool (see also haemorrhagic diarrhoea)",
      "count": 97
    },
    {
      "term": "Musculoskeletal disorder NOS",
      "count": 94
    },
    {
      "term": "Walking difficulty",
      "count": 94
    },
    {
      "term": "Blood in faeces",
      "count": 93
    },
    {
      "term": "Nausea",
      "count": 93
    },
    {
      "term": "Shaking",
      "count": 93
    },
    {
      "term": "Malaise",
      "count": 92
    },
    {
      "term": "Partial lack of efficacy",
      "count": 91
    },
    {
      "term": "Cough",
      "count": 90
    },
    {
      "term": "Elevated total bilirubin",
      "count": 90
    },
    {
      "term": "Fever",
      "count": 85
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 84
    },
    {
      "term": "Unable to stand",
      "count": 84
    },
    {
      "term": "Anxiety",
      "count": 82
    },
    {
      "term": "Not drinking",
      "count": 82
    },
    {
      "term": "Azotaemia",
      "count": 81
    },
    {
      "term": "Vocalisation",
      "count": 81
    },
    {
      "term": "Decreased urine concentration",
      "count": 80
    },
    {
      "term": "Pancreatitis",
      "count": 80
    },
    {
      "term": "Limping",
      "count": 79
    },
    {
      "term": "Pale mucous membrane",
      "count": 78
    },
    {
      "term": "Lameness",
      "count": 77
    },
    {
      "term": "Proprioception deficit",
      "count": 75
    },
    {
      "term": "Arthritis",
      "count": 74
    },
    {
      "term": "Appetite loss",
      "count": 73
    },
    {
      "term": "Mucous stool",
      "count": 73
    },
    {
      "term": "Drinking a lot",
      "count": 72
    },
    {
      "term": "Elevated lipase",
      "count": 71
    },
    {
      "term": "Reluctant to move",
      "count": 70
    },
    {
      "term": "Disorientation",
      "count": 69
    },
    {
      "term": "Pacing",
      "count": 69
    },
    {
      "term": "Renal failure",
      "count": 69
    },
    {
      "term": "Thrombocytopenia",
      "count": 67
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 65
    },
    {
      "term": "Drooling",
      "count": 65
    },
    {
      "term": "Falling",
      "count": 64
    },
    {
      "term": "Abdominal pain",
      "count": 63
    },
    {
      "term": "Hypoproteinaemia",
      "count": 63
    },
    {
      "term": "Thrombocytosis",
      "count": 63
    },
    {
      "term": "Emesis",
      "count": 62
    },
    {
      "term": "Hyperkalaemia",
      "count": 62
    },
    {
      "term": "Low platelet count",
      "count": 62
    },
    {
      "term": "Uncomfortable",
      "count": 61
    },
    {
      "term": "Bone and joint disorder NOS",
      "count": 60
    },
    {
      "term": "Underdose",
      "count": 60
    },
    {
      "term": "Elevated cholesterol (total)",
      "count": 58
    },
    {
      "term": "Sleepiness - systemic disorder",
      "count": 57
    },
    {
      "term": "Itching",
      "count": 56
    },
    {
      "term": "Medication error NOS",
      "count": 56
    },
    {
      "term": "Melaena",
      "count": 53
    },
    {
      "term": "Elevated globulins",
      "count": 52
    }
  ]
}