{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Deafness",
      "count": 2101
    },
    {
      "term": "Loss of hearing",
      "count": 623
    },
    {
      "term": "Temporary deafness",
      "count": 489
    },
    {
      "term": "Partial deafness",
      "count": 384
    },
    {
      "term": "Vomiting",
      "count": 343
    },
    {
      "term": "PR-EAR(S), LESION(S)",
      "count": 321
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 298
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 208
    },
    {
      "term": "Diarrhoea",
      "count": 192
    },
    {
      "term": "Emesis",
      "count": 187
    },
    {
      "term": "Hearing affected",
      "count": 163
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 128
    },
    {
      "term": "Anorexia",
      "count": 127
    },
    {
      "term": "Death by euthanasia",
      "count": 123
    },
    {
      "term": "Accidental exposure",
      "count": 113
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 110
    },
    {
      "term": "Ataxia",
      "count": 102
    },
    {
      "term": "Depression",
      "count": 100
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 89
    },
    {
      "term": "Pinnal erythema",
      "count": 84
    },
    {
      "term": "Not eating",
      "count": 82
    },
    {
      "term": "Head tilt - ear disorder",
      "count": 81
    },
    {
      "term": "Pruritus",
      "count": 78
    },
    {
      "term": "Death",
      "count": 76
    },
    {
      "term": "Seizure NOS",
      "count": 74
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 72
    },
    {
      "term": "Decreased appetite",
      "count": 71
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 71
    },
    {
      "term": "Shaking",
      "count": 71
    },
    {
      "term": "Polyuria",
      "count": 70
    },
    {
      "term": "Weight loss",
      "count": 69
    },
    {
      "term": "Ear discharge",
      "count": 66
    },
    {
      "term": "Polydipsia",
      "count": 66
    },
    {
      "term": "Application site erythema",
      "count": 63
    },
    {
      "term": "Otitis externa",
      "count": 61
    },
    {
      "term": "Ear infection NOS",
      "count": 59
    },
    {
      "term": "Panting",
      "count": 57
    },
    {
      "term": "Fever",
      "count": 55
    },
    {
      "term": "Pain NOS",
      "count": 52
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 50
    },
    {
      "term": "Pinnal irritation",
      "count": 50
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 48
    },
    {
      "term": "External ear disorder NOS",
      "count": 48
    },
    {
      "term": "Head shake - ear disorder",
      "count": 48
    },
    {
      "term": "Lack of efficacy (bacteria) - NOS",
      "count": 48
    },
    {
      "term": "Leucocytosis NOS",
      "count": 47
    },
    {
      "term": "Loose stool",
      "count": 45
    },
    {
      "term": "Other ear disorder NOS",
      "count": 43
    },
    {
      "term": "Vestibular disorder NOS",
      "count": 43
    },
    {
      "term": "Anaemia NOS",
      "count": 42
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 42
    },
    {
      "term": "Ocular discharge",
      "count": 41
    },
    {
      "term": "Vocalisation",
      "count": 41
    },
    {
      "term": "Application site inflammation",
      "count": 40
    },
    {
      "term": "Emesis (multiple)",
      "count": 39
    },
    {
      "term": "Skin lesion NOS",
      "count": 39
    },
    {
      "term": "Restlessness",
      "count": 37
    },
    {
      "term": "Inappetence",
      "count": 36
    },
    {
      "term": "Trembling",
      "count": 36
    },
    {
      "term": "Application site pain",
      "count": 35
    },
    {
      "term": "Corneal ulcer",
      "count": 35
    },
    {
      "term": "Elevated creatinine",
      "count": 35
    },
    {
      "term": "Elevated liver enzymes",
      "count": 35
    },
    {
      "term": "Abnormal cytology",
      "count": 34
    },
    {
      "term": "Anxiety",
      "count": 34
    },
    {
      "term": "Nystagmus",
      "count": 34
    },
    {
      "term": "Skin ulcer",
      "count": 34
    },
    {
      "term": "Dehydration",
      "count": 33
    },
    {
      "term": "Urticaria",
      "count": 33
    },
    {
      "term": "Neutrophilia",
      "count": 32
    },
    {
      "term": "Dermatitis",
      "count": 31
    },
    {
      "term": "Falling",
      "count": 31
    },
    {
      "term": "Weakness",
      "count": 30
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 29
    },
    {
      "term": "Bloody diarrhoea",
      "count": 29
    },
    {
      "term": "Convulsion",
      "count": 29
    },
    {
      "term": "Drug administration duration too long",
      "count": 29
    },
    {
      "term": "Crust",
      "count": 28
    },
    {
      "term": "Elevated total bilirubin",
      "count": 28
    },
    {
      "term": "Facial oedema",
      "count": 28
    },
    {
      "term": "Vesicle",
      "count": 28
    },
    {
      "term": "Anaphylaxis",
      "count": 27
    },
    {
      "term": "Skin hyperaemia",
      "count": 27
    },
    {
      "term": "Cough",
      "count": 26
    },
    {
      "term": "Rash",
      "count": 26
    },
    {
      "term": "Skin scab",
      "count": 26
    },
    {
      "term": "Underdose",
      "count": 26
    },
    {
      "term": "Walking difficulty",
      "count": 26
    },
    {
      "term": "Ear pain",
      "count": 25
    },
    {
      "term": "Itching",
      "count": 25
    },
    {
      "term": "Pale mucous membrane",
      "count": 25
    },
    {
      "term": "Disorientation",
      "count": 24
    },
    {
      "term": "Hypersalivation",
      "count": 24
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 24
    },
    {
      "term": "Lack of efficacy (ectoparasite) - flea",
      "count": 24
    },
    {
      "term": "Not drinking",
      "count": 24
    },
    {
      "term": "Reddening of the skin",
      "count": 24
    },
    {
      "term": "Reluctant to move",
      "count": 24
    },
    {
      "term": "Thrombocytopenia",
      "count": 24
    },
    {
      "term": "Urinary incontinence",
      "count": 24
    }
  ]
}