{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Death by euthanasia",
      "count": 86
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 56
    },
    {
      "term": "Death",
      "count": 40
    },
    {
      "term": "Vomiting",
      "count": 40
    },
    {
      "term": "Elevated total bilirubin",
      "count": 39
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 37
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 36
    },
    {
      "term": "Anorexia",
      "count": 36
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 34
    },
    {
      "term": "Diarrhoea",
      "count": 33
    },
    {
      "term": "Icterus",
      "count": 30
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 27
    },
    {
      "term": "Neutrophilia",
      "count": 26
    },
    {
      "term": "Anaemia NOS",
      "count": 25
    },
    {
      "term": "Dehydration",
      "count": 24
    },
    {
      "term": "Monocytosis",
      "count": 23
    },
    {
      "term": "Thrombocytopenia",
      "count": 23
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 21
    },
    {
      "term": "Seizure NOS",
      "count": 21
    },
    {
      "term": "Hyperglycaemia",
      "count": 20
    },
    {
      "term": "Elevated creatinine",
      "count": 19
    },
    {
      "term": "Elevated liver enzymes NOS",
      "count": 19
    },
    {
      "term": "Hypokalaemia",
      "count": 19
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 18
    },
    {
      "term": "Decreased appetite",
      "count": 18
    },
    {
      "term": "Fever",
      "count": 18
    },
    {
      "term": "Gall bladder & bile duct disorder NOS",
      "count": 18
    },
    {
      "term": "Sudden death",
      "count": 18
    },
    {
      "term": "Abdominal pain",
      "count": 17
    },
    {
      "term": "Heart murmur",
      "count": 17
    },
    {
      "term": "Weight loss",
      "count": 17
    },
    {
      "term": "Azotaemia",
      "count": 16
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 16
    },
    {
      "term": "Hypochloraemia",
      "count": 16
    },
    {
      "term": "Pale mucous membrane",
      "count": 16
    },
    {
      "term": "Elevated liver enzymes",
      "count": 15
    },
    {
      "term": "Dry mucous membrane",
      "count": 14
    },
    {
      "term": "Elevated amylase",
      "count": 14
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 14
    },
    {
      "term": "Hepatopathy",
      "count": 14
    },
    {
      "term": "High pancreatic-specific lipase",
      "count": 14
    },
    {
      "term": "Hyperphosphataemia",
      "count": 14
    },
    {
      "term": "Hypoglycaemia",
      "count": 14
    },
    {
      "term": "Bruising",
      "count": 13
    },
    {
      "term": "Eosinopenia",
      "count": 13
    },
    {
      "term": "Hepatomegaly",
      "count": 13
    },
    {
      "term": "Hyperthermia",
      "count": 13
    },
    {
      "term": "Hypotension",
      "count": 13
    },
    {
      "term": "Lymphopenia",
      "count": 13
    },
    {
      "term": "Tachycardia",
      "count": 13
    },
    {
      "term": "Abdominal effusion",
      "count": 12
    },
    {
      "term": "Decreased haemoglobin",
      "count": 12
    },
    {
      "term": "Drug dose omission",
      "count": 12
    },
    {
      "term": "Hypoproteinaemia",
      "count": 12
    },
    {
      "term": "Jaundice",
      "count": 12
    },
    {
      "term": "Lateral recumbency",
      "count": 12
    },
    {
      "term": "Pancreatitis NOS",
      "count": 12
    },
    {
      "term": "Polyuria",
      "count": 12
    },
    {
      "term": "Cough",
      "count": 11
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 11
    },
    {
      "term": "Overdose",
      "count": 11
    },
    {
      "term": "Polydipsia",
      "count": 11
    },
    {
      "term": "Regurgitation",
      "count": 11
    },
    {
      "term": "Ataxia",
      "count": 10
    },
    {
      "term": "Collapse NOS (see also Cardio-vascular and Neurological disorders)",
      "count": 10
    },
    {
      "term": "Decreased percentage of reticulocytes",
      "count": 10
    },
    {
      "term": "Elevated lipase",
      "count": 10
    },
    {
      "term": "Hyponatremia",
      "count": 10
    },
    {
      "term": "Leucocytosis NOS",
      "count": 10
    },
    {
      "term": "Prolonged activated partial thrombin time (APTT)",
      "count": 10
    },
    {
      "term": "Bloody diarrhoea",
      "count": 9
    },
    {
      "term": "Bradycardia",
      "count": 9
    },
    {
      "term": "Elevated cholesterol (total)",
      "count": 9
    },
    {
      "term": "Elevated globulins",
      "count": 9
    },
    {
      "term": "Febrile",
      "count": 9
    },
    {
      "term": "Hypertension",
      "count": 9
    },
    {
      "term": "Injection site swelling",
      "count": 9
    },
    {
      "term": "Loose stool",
      "count": 9
    },
    {
      "term": "Not eating",
      "count": 9
    },
    {
      "term": "Ocular discharge",
      "count": 9
    },
    {
      "term": "Panting",
      "count": 9
    },
    {
      "term": "Septicaemia",
      "count": 9
    },
    {
      "term": "Tachypnoea",
      "count": 9
    },
    {
      "term": "Tense abdomen",
      "count": 9
    },
    {
      "term": "Cardiac arrest",
      "count": 8
    },
    {
      "term": "Dull",
      "count": 8
    },
    {
      "term": "Hypernatremia",
      "count": 8
    },
    {
      "term": "Laboured breathing",
      "count": 8
    },
    {
      "term": "Limb weakness",
      "count": 8
    },
    {
      "term": "Weakness",
      "count": 8
    },
    {
      "term": "Bilirubinuria",
      "count": 7
    },
    {
      "term": "Crackles on auscultation",
      "count": 7
    },
    {
      "term": "Decreased haematocrit",
      "count": 7
    },
    {
      "term": "Decreased red blood cell count",
      "count": 7
    },
    {
      "term": "Discoloured urine",
      "count": 7
    },
    {
      "term": "Dyspnoea",
      "count": 7
    },
    {
      "term": "Hypothermia",
      "count": 7
    },
    {
      "term": "Increased coagulation time",
      "count": 7
    },
    {
      "term": "Increased percentage reticulocytes",
      "count": 7
    },
    {
      "term": "Urine abnormalities NOS",
      "count": 7
    }
  ]
}