{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 248
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 213
    },
    {
      "term": "Death by euthanasia",
      "count": 195
    },
    {
      "term": "Diarrhoea",
      "count": 195
    },
    {
      "term": "Death",
      "count": 188
    },
    {
      "term": "Seizure NOS",
      "count": 135
    },
    {
      "term": "Anorexia",
      "count": 127
    },
    {
      "term": "Cough",
      "count": 126
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 123
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 93
    },
    {
      "term": "Weight loss",
      "count": 87
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 84
    },
    {
      "term": "Decreased appetite",
      "count": 83
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 83
    },
    {
      "term": "Not eating",
      "count": 83
    },
    {
      "term": "Ataxia",
      "count": 82
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 77
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 74
    },
    {
      "term": "Elevated creatinine",
      "count": 71
    },
    {
      "term": "Emesis",
      "count": 66
    },
    {
      "term": "Breathing difficulty",
      "count": 62
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 60
    },
    {
      "term": "Panting",
      "count": 60
    },
    {
      "term": "Leucocytosis NOS",
      "count": 58
    },
    {
      "term": "Pulmonary oedema",
      "count": 57
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 55
    },
    {
      "term": "Tachycardia",
      "count": 47
    },
    {
      "term": "Dyspnoea",
      "count": 46
    },
    {
      "term": "Shaking",
      "count": 45
    },
    {
      "term": "Hyperphosphataemia",
      "count": 44
    },
    {
      "term": "Accidental exposure",
      "count": 42
    },
    {
      "term": "Pale mucous membrane",
      "count": 41
    },
    {
      "term": "Anaemia NOS",
      "count": 40
    },
    {
      "term": "Cardiac enlargement",
      "count": 40
    },
    {
      "term": "Neutrophilia",
      "count": 39
    },
    {
      "term": "Polydipsia",
      "count": 39
    },
    {
      "term": "Hyperglycaemia",
      "count": 37
    },
    {
      "term": "Laboured breathing",
      "count": 36
    },
    {
      "term": "Respiratory distress",
      "count": 36
    },
    {
      "term": "Overdose",
      "count": 35
    },
    {
      "term": "Polyuria",
      "count": 35
    },
    {
      "term": "Renal failure",
      "count": 35
    },
    {
      "term": "Weakness",
      "count": 35
    },
    {
      "term": "Elevated liver enzymes",
      "count": 34
    },
    {
      "term": "Heart murmur",
      "count": 34
    },
    {
      "term": "Inappetence",
      "count": 34
    },
    {
      "term": "Increased respiratory rate",
      "count": 34
    },
    {
      "term": "Syncope",
      "count": 33
    },
    {
      "term": "Tachypnoea",
      "count": 33
    },
    {
      "term": "Dehydration",
      "count": 31
    },
    {
      "term": "Lack of efficacy (ectoparasite) - flea",
      "count": 31
    },
    {
      "term": "Underdose",
      "count": 31
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 29
    },
    {
      "term": "Hypochloraemia",
      "count": 29
    },
    {
      "term": "Cyanosis",
      "count": 28
    },
    {
      "term": "Cardiac arrest",
      "count": 27
    },
    {
      "term": "Depression",
      "count": 27
    },
    {
      "term": "Falling",
      "count": 27
    },
    {
      "term": "Fever",
      "count": 27
    },
    {
      "term": "Hyperkalaemia",
      "count": 27
    },
    {
      "term": "Loose stool",
      "count": 27
    },
    {
      "term": "Vocalisation",
      "count": 27
    },
    {
      "term": "Anaphylaxis",
      "count": 26
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 26
    },
    {
      "term": "Emesis (multiple)",
      "count": 26
    },
    {
      "term": "Congestive heart failure",
      "count": 25
    },
    {
      "term": "Tremor",
      "count": 25
    },
    {
      "term": "Urinary incontinence",
      "count": 25
    },
    {
      "term": "Crackles on auscultation",
      "count": 24
    },
    {
      "term": "Elevated renal parameters",
      "count": 24
    },
    {
      "term": "Elevated total bilirubin",
      "count": 24
    },
    {
      "term": "Hypokalaemia",
      "count": 24
    },
    {
      "term": "Limb weakness",
      "count": 24
    },
    {
      "term": "Low sodium-potassium ratio (Na:K ratio)",
      "count": 24
    },
    {
      "term": "Monocytosis",
      "count": 24
    },
    {
      "term": "Trembling",
      "count": 24
    },
    {
      "term": "Azotaemia",
      "count": 23
    },
    {
      "term": "Disorientation",
      "count": 22
    },
    {
      "term": "Lack of efficacy (endoparasite) - heartworm",
      "count": 22
    },
    {
      "term": "Thrombocytopenia",
      "count": 22
    },
    {
      "term": "Abnormal breathing",
      "count": 21
    },
    {
      "term": "Hyponatremia",
      "count": 21
    },
    {
      "term": "Anxiety",
      "count": 20
    },
    {
      "term": "Ascites",
      "count": 20
    },
    {
      "term": "Cardiac disorder NOS",
      "count": 20
    },
    {
      "term": "Heart failure",
      "count": 20
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 20
    },
    {
      "term": "Lateral recumbency",
      "count": 20
    },
    {
      "term": "Proteinuria",
      "count": 20
    },
    {
      "term": "Twitching",
      "count": 20
    },
    {
      "term": "Bloody diarrhoea",
      "count": 19
    },
    {
      "term": "Decreased urine concentration",
      "count": 19
    },
    {
      "term": "Distension of abdomen",
      "count": 19
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 19
    },
    {
      "term": "Lymphopenia",
      "count": 19
    },
    {
      "term": "Pleural effusion",
      "count": 19
    },
    {
      "term": "Pneumonia",
      "count": 19
    },
    {
      "term": "Restlessness",
      "count": 19
    },
    {
      "term": "Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders')",
      "count": 18
    },
    {
      "term": "Elevated amylase",
      "count": 18
    }
  ]
}